KEGG   ORTHOLOGY: K13578Help
Entry
K13578                      KO                                     

Name
BMPR1B, ALK6, CDw293
Definition
bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
Pathway
ko04013  MAPK signaling pathway - fly
ko04060  Cytokine-cytokine receptor interaction
ko04350  TGF-beta signaling pathway
ko04360  Axon guidance
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko05418  Fluid shear stress and atherosclerosis
Module
M00679  BMP signaling
Disease
H00468  Acromesomelic dysplasia with genital anomalies
H00482  Brachydactyly
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04013 MAPK signaling pathway - fly
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
   04350 TGF-beta signaling pathway
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
   04390 Hippo signaling pathway
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 Organismal Systems
  Development
   04360 Axon guidance
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
Protein kinases [BR:ko01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
CD molecules [BR:ko04090]
 Proteins
  K13578  CDw293, BMPR1B; bone morphogenetic protein receptor, type IB
BRITE hierarchy
Other DBs
GO: 0005025
Genes
HSA: 658(BMPR1B)
PTR: 461683(BMPR1B)
PPS: 100991587(BMPR1B)
GGO: 101127602(BMPR1B)
PON: 100444576(BMPR1B)
NLE: 100595681(BMPR1B)
MCC: 705474(BMPR1B)
MCF: 102136230(BMPR1B)
RRO: 104679852(BMPR1B)
RBB: 108531867(BMPR1B)
CJC: 100397724(BMPR1B)
SBQ: 101046738(BMPR1B)
MMU: 12167(Bmpr1b)
RNO: 310914(Bmpr1b)
CGE: 100774629(Bmpr1b)
NGI: 103728063(Bmpr1b)
HGL: 101710196(Bmpr1b)
CCAN: 109703066(Bmpr1b)
OCU: 100351275(BMPR1B)
TUP: 102496847
CFA: 478484(BMPR1B)
AML: 100467049(BMPR1B)
UMR: 103677908(BMPR1B)
ORO: 101373181(BMPR1B)
FCA: 101082489(BMPR1B)
PTG: 102968798(BMPR1B)
AJU: 106983784(BMPR1B)
BTA: 407128(BMPR1B)
BOM: 102284193(BMPR1B)
BIU: 109560330(BMPR1B)
PHD: 102333540(BMPR1B)
CHX: 100861211(BMPR1B)
OAS: 443454(BMPR1B)
SSC: 396691(BMPR1B)
CFR: 102511519(BMPR1B)
CDK: 105089530(BMPR1B)
BACU: 103017850(BMPR1B)
LVE: 103077119(BMPR1B)
OOR: 101287667(BMPR1B)
ECB: 100053554(BMPR1B)
EPZ: 103557055(BMPR1B)
EAI: 106826733(BMPR1B)
MYB: 102255240(BMPR1B)
MYD: 102764015(BMPR1B)
HAI: 109385323(BMPR1B)
RSS: 109452295(BMPR1B)
PALE: 102896177(BMPR1B)
LAV: 100660194(BMPR1B)
TMU: 101344166
MDO: 100016370(BMPR1B)
SHR: 100920492(BMPR1B) 100925733
OAA: 100086574
GGA: 396030(BMPR1B)
MGP: 100543302(BMPR1B)
CJO: 107313618(BMPR1B)
APLA: 101794439(BMPR1B)
ACYG: 106041244(BMPR1B)
TGU: 100218713(BMPR1B)
GFR: 102045388(BMPR1B)
FAB: 101818178(BMPR1B)
PHI: 102103410(BMPR1B)
PMAJ: 107203490(BMPR1B)
CCW: 104697196(BMPR1B)
FPG: 101913989(BMPR1B)
FCH: 102054291(BMPR1B)
CLV: 102092756(BMPR1B)
EGZ: 104122617(BMPR1B)
AAM: 106491882(BMPR1B)
ASN: 102369865(BMPR1B)
AMJ: 102561072(BMPR1B)
PSS: 102449724(BMPR1B)
CMY: 102945112(BMPR1B)
CPIC: 101946330(BMPR1B)
ACS: 100553122(bmpr1b)
PVT: 110081721(BMPR1B)
GJA: 107116711(BMPR1B)
XTR: 780089(bmpr1b)
NPR: 108785433(BMPR1B)
DRE: 100149664(bmpr1bb) 30742(bmpr1ba)
IPU: 108277027(bmpr1b)
AMEX: 111189508 111195008(bmpr1b)
LCO: 104920273(bmpr1b) 104924706
NCC: 104950677(bmpr1b) 104962645
OLA: 101163987 101171086(bmpr1b)
XMA: 102226015 102230081(bmpr1b)
PRET: 103470230(bmpr1b) 103473770
NFU: 107373829 107394018(bmpr1b)
LCF: 108878299(bmpr1b) 108879878
HCQ: 109526066 109526258(bmpr1b)
ELS: 105014580(bmpr1b) 105025159
SFM: 108934995 108938076(bmpr1b)
LCM: 102364169(BMPR1B)
CMK: 103184492(bmpr1b)
SPU: 592872
APLC: 110978597
SKO: 100303460(bmpR1)
DME: Dmel_CG14026(tkv)
DSI: Dsimw501_GD22659(Dsim_GD22659)
MDE: 101900564
AAG: 5571852
AME: 408442(tkv)
BIM: 100747692
BTER: 105665609
SOC: 105194209
AEC: 105143402
ACEP: 105627533
PBAR: 105431245
HST: 105189577
CFO: 105259212
LHU: 105677089
PGC: 109853566
NVI: 100116851
TCA: 659260(thickveins)
NVL: 108557405
BMOR: 101741200
PRAP: 110999119
API: 100167815
DNX: 107170416
ZNE: 110830227
FCD: 110858668
CEL: CELE_C32D5.2(sma-6)
CBR: CBG02627(Cbr-sma-6)
BMY: Bm1_06550
TSP: Tsp_04000
CRG: 105332635
MYI: 110451209
OBI: 106873837
LAK: 106160415
EPA: 110232951
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9178898
  Authors
Ide H, Katoh M, Sasaki H, Yoshida T, Aoki K, Nawa Y, Osada Y, Sugimura T, Terada M
  Title
Cloning of human bone morphogenetic protein type IB receptor (BMPR-IB) and its expression in prostate cancer in comparison with other BMPRs.
  Journal
Oncogene 14:1377-82 (1997)
DOI:10.1038/sj.onc.1200964
  Sequence
[hsa:658]
Reference
  Authors
Graul-Neumann LM, Deichsel A, Wille U, Kakar N, Koll R, Bassir C, Ahmad J, Cormier-Daire V, Mundlos S, Kubisch C, Borck G, Klopocki E, Mueller TD, Doelken SC, Seemann P
  Title
Homozygous missense and nonsense mutations in BMPR1B cause acromesomelic chondrodysplasia-type Grebe.
  Journal
Eur J Hum Genet 22:726-33 (2014)
DOI:10.1038/ejhg.2013.222
  Sequence
[hsa:658]

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