KEGG   ORTHOLOGY: K13744Help
Entry
K13744                      KO                                     
Name
SGEF
Definition
SH3 domain-containing guanine exchange factor
Pathway
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    K13744  SGEF; SH3 domain-containing guanine exchange factor
BRITE hierarchy
Genes
HSA: 
26084(ARHGEF26)
PTR: 
470971(ARHGEF26)
PPS: 
100973709(ARHGEF26)
GGO: 
101127701(ARHGEF26)
PON: 
MCC: 
MMU: 
622434(Arhgef26)
RNO: 
310460(Arhgef26)
CFA: 
611857(ARHGEF26)
AML: 
FCA: 
101090134(ARHGEF26)
BTA: 
531741(ARHGEF26)
SSC: 
100626582(ARHGEF26)
MDO: 
100019904(ARHGEF26)
SHR: 
100921075(ARHGEF26)
OAA: 
100080472
GGA: 
429163(ARHGEF26)
TGU: 
100226493(ARHGEF26)
ACS: 
100552711
XTR: 
100495357
TRU: 
101079375
OLA: 
101154796
CIN: 
100177782
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ellerbroek SM, Wennerberg K, Arthur WT, Dunty JM, Bowman DR, DeMali KA, Der C, Burridge K
  Title
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.
  Journal
Mol Biol Cell 15:3309-19 (2004)
Reference
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
Reference
  Authors
van Buul JD, Allingham MJ, Samson T, Meller J, Boulter E, Garcia-Mata R, Burridge K
  Title
RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration.
  Journal
J Cell Biol 178:1279-93 (2007)
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