KEGG   ORTHOLOGY: K14021Help
Entry
K14021                      KO                                     

Name
BAK, BAK1
Definition
Bcl-2 homologous antagonist/killer
Pathway
Platinum drug resistance
Protein processing in endoplasmic reticulum
Apoptosis
Apoptosis - multiple species
Human papillomavirus infection
Kaposi's sarcoma-associated herpesvirus infection
Pathways in cancer
Transcriptional misregulation in cancer
Viral carcinogenesis
MicroRNAs in cancer
Colorectal cancer
Pancreatic cancer
Endometrial cancer
Glioma
Thyroid cancer
Basal cell carcinoma
Melanoma
Chronic myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Breast cancer
Hepatocellular carcinoma
Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   04215 Apoptosis - multiple species
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05202 Transcriptional misregulation in cancers
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05206 MicroRNAs in cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05203 Viral carcinogenesis
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05210 Colorectal cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05212 Pancreatic cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05225 Hepatocellular carcinoma
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05226 Gastric cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05214 Glioma
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05216 Thyroid cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05220 Chronic myeloid leukemia
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05217 Basal cell carcinoma
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05218 Melanoma
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05213 Endometrial cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05224 Breast cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05222 Small cell lung cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05223 Non-small cell lung cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05165 Human papillomavirus infection
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
  Drug resistance
   01524 Platinum drug resistance
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
Transporters [BR:ko02000]
 Other Transporters
  Pores ion channels
   K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
BRITE hierarchy
Other DBs
Genes
HSA: 
578(BAK1)
PTR: 
462616(BAK1)
PPS: 
100983246(BAK1)
GGO: 
101154455(BAK1)
PON: 
NLE: 
100588483(BAK1)
MCC: 
MCF: 
102142357(BAK1)
CSAB: 
103221651(BAK1)
RRO: 
RBB: 
108516259(BAK1)
CJC: 
100387945(BAK1)
SBQ: 
101041291(BAK1)
MMU: 
12018(Bak1)
RNO: 
116502(Bak1)
CGE: 
100689368(Bak1)
NGI: 
103739733(Bak1)
HGL: 
101707336(Bak1)
CCAN: 
109686692(Bak1)
OCU: 
100342046(BAK1)
TUP: 
102476690(BAK1)
CFA: 
481744(BAK1)
AML: 
100472241(BAK1)
UMR: 
FCA: 
101093435(BAK1)
PTG: 
102970767(BAK1)
AJU: 
106976101(BAK1)
BTA: 
514090(BAK1)
BOM: 
102266544(BAK1)
BIU: 
109577301(BAK1)
PHD: 
CHX: 
102170562(BAK1)
OAS: 
443062(BAK1)
SSC: 
397543(BAK1)
CFR: 
102513729(BAK1)
CDK: 
105101376(BAK1)
BACU: 
LVE: 
ECB: 
100061755(BAK1)
EPZ: 
103544222(BAK1)
EAI: 
106834586(BAK1)
MYB: 
102240268(BAK1)
MYD: 
102764949(BAK1)
HAI: 
109392454(BAK1)
RSS: 
109450995(BAK1)
PALE: 
102883540(BAK1)
LAV: 
100669799(BAK1)
MDO: 
100027503(BAK1)
SHR: 
100916731(BAK1)
GGA: 
419912(BAK1)
MGP: 
100544475(BAK1)
CJO: 
107324870(BAK1)
APLA: 
101789424(BAK1)
ACYG: 
106046164(BAK1)
GFR: 
102040914(BAK1)
FAB: 
101810079(BAK1)
PHI: 
102107798(BAK1)
PMAJ: 
107215027(BAK1)
CCW: 
104692533(BAK1)
FPG: 
101924229(BAK1)
FCH: 
102047828(BAK1)
CLV: 
102098929(BAK1)
AAM: 
106483956(BAK1)
ASN: 
102374149(BAK1)
AMJ: 
102570499(BAK1)
PSS: 
102449586(BAK1)
CMY: 
102946475(BAK1)
CPIC: 
101935419(BAK1)
ACS: 
100564650(bak1)
PVT: 
110080152(BAK1)
PBI: 
103053500(BAK1)
GJA: 
107117593(BAK1)
XLA: 
734644(bak1.L)
NPR: 
108787278(BAK1)
SFM: 
108931251(bak1)
LCM: 
CMK: 
BFO: 
SPU: 
APLC: 
SKO: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
EPA: 
ADF: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruiz-Vela A, Opferman JT, Cheng EH, Korsmeyer SJ
  Title
Proapoptotic BAX and BAK control multiple initiator caspases.
  Journal
EMBO Rep 6:379-85 (2005)
DOI:10.1038/sj.embor.7400375
  Sequence
[mmu:12018]
Reference
PMID:7715730
  Authors
Chittenden T, Harrington EA, O'Connor R, Flemington C, Lutz RJ, Evan GI, Guild BC
  Title
Induction of apoptosis by the Bcl-2 homologue Bak.
  Journal
Nature 374:733-6 (1995)
DOI:10.1038/374733a0
  Sequence
[hsa:578]

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