KEGG   ORTHOLOGY: K14021Help
Entry
K14021                      KO                                     

Name
BAK, BAK1
Definition
Bcl-2 homologous antagonist/killer
Pathway
Protein processing in endoplasmic reticulum
Viral carcinogenesis
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
   05203 Viral carcinogenesis
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
BRITE hierarchy
Genes
HSA: 
578(BAK1)
PTR: 
462616(BAK1)
PPS: 
GGO: 
101154455(BAK1)
PON: 
MCC: 
706534(BAK1)
MCF: 
MMU: 
12018(Bak1)
RNO: 
116502(Bak1)
CGE: 
100689368(Bak1)
HGL: 
TUP: 
102476690(BAK1)
CFA: 
481744(BAK1)
AML: 
FCA: 
101093435(BAK1)
PTG: 
102970767(BAK1)
BTA: 
514090(BAK1)
BOM: 
PHD: 
CHX: 
SSC: 
397543(BAK)
CFR: 
ECB: 
MYB: 
MYD: 
102764949(BAK1)
PALE: 
MDO: 
100027503(BAK1)
SHR: 
100916731(BAK1)
GGA: 
419912(BAK1)
MGP: 
TGU: 
100224672(BAK1)
FAB: 
PHI: 
APLA: 
101789424(BAK1)
FPG: 
101924229(BAK1)
FCH: 
102047828(BAK1)
CLV: 
102098929(BAK1)
ASN: 
102374149(BAK1)
PSS: 
102449586(BAK1)
CMY: 
102946475(BAK1)
ACS: 
XLA: 
734644(bak1)
XTR: 
LCM: 
102345216(BAK1)
BFO: 
SPU: 
SMM: 
NVE: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruiz-Vela A, Opferman JT, Cheng EH, Korsmeyer SJ
  Title
Proapoptotic BAX and BAK control multiple initiator caspases.
  Journal
EMBO Rep 6:379-85 (2005)
Reference
  Authors
Moldoveanu T, Liu Q, Tocilj A, Watson M, Shore G, Gehring K
  Title
The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site.
  Journal
Mol Cell 24:677-88 (2006)

DBGET integrated database retrieval system