KEGG   ORTHOLOGY: K14077Help
Entry
K14077                      KO                                     

Name
TPCN2
Definition
two pore calcium channel protein 2
Pathway
Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Digestive system
   04972 Pancreatic secretion
    K14077  TPCN2; two pore calcium channel protein 2
Ion channels [BR:ko04040]
 Related to voltage-gated cation channels
  CatSper and two-pore channel
   K14077  TPCN2; two pore calcium channel protein 2
BRITE hierarchy
Other DBs
Genes
HSA: 
219931(TPCN2)
PTR: 
747605(TPCN2)
PPS: 
100971084(TPCN2)
GGO: 
101128404(TPCN2)
PON: 
100444397(TPCN2)
MCC: 
709391(TPCN2)
MCF: 
102137514(TPCN2)
MMU: 
233979(Tpcn2)
RNO: 
309139(Tpcn2)
CGE: 
100755221(Tpcn2)
HGL: 
101712986(Tpcn2)
TUP: 
102491632(TPCN2)
CFA: 
483683(TPCN2)
AML: 
100473327(TPCN2)
FCA: 
101086345(TPCN2)
PTG: 
102966890(TPCN2)
BTA: 
516679(TPCN2)
BOM: 
102270254(TPCN2)
PHD: 
102333222(TPCN2)
CHX: 
102189285(TPCN2)
SSC: 
100523421(TPCN2)
CFR: 
102521432(TPCN2)
BACU: 
103012938(TPCN2)
LVE: 
103090869(TPCN2)
ECB: 
102150167(TPCN2)
MYB: 
102249015(TPCN2)
MYD: 
102758401(TPCN2)
PALE: 
102893492(TPCN2)
SHR: 
OAA: 
100074753(TPCN2)
GGA: 
423141(TPCN2)
MGP: 
TGU: 
100227742(TPCN2)
FAB: 
101808920(TPCN2)
PHI: 
102099845(TPCN2)
APLA: 
101790097(TPCN2)
FPG: 
101918177(TPCN2)
FCH: 
102055799(TPCN2)
CLV: 
102096153(TPCN2)
ASN: 
102384386(TPCN2)
AMJ: 
102570546(TPCN2)
PSS: 
102447456(TPCN2)
CMY: 
102937752(TPCN2)
ACS: 
100565414(tpcn2)
PBI: 
XLA: 
734733(tpcn2)
XTR: 
100492057(tpcn2)
DRE: 
777614(tpcn2)
MZE: 
OLA: 
XMA: 
LCM: 
102361800(TPCN2)
CMK: 
103175101(tpcn2)
BFO: 
CIN: 
SPU: 
592190(TPC2)
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A
  Title
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
  Journal
Curr Biol 20:703-9 (2010)
Reference
  Authors
Zhu MX, Ma J, Parrington J, Calcraft PJ, Galione A, Evans AM
  Title
Calcium signaling via two-pore channels: local or global, that is the question.
  Journal
Am J Physiol Cell Physiol 298:C430-41 (2010)
Reference
  Authors
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX
  Title
NAADP mobilizes calcium from acidic organelles through two-pore channels.
  Journal
Nature 459:596-600 (2009)

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