KEGG   ORTHOLOGY: K14152Help
Entry
K14152                      KO                                     

Name
HIS4
Definition
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Pathway
Histidine metabolism
Biosynthesis of amino acids
Module
M00026  
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01230 Biosynthesis of amino acids
    K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
  Amino acid metabolism
   00340 Histidine metabolism
    K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Histidine metabolism
    M00026  Histidine biosynthesis, PRPP => histidine
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
BRITE hierarchy
Other DBs
Genes
SCE: 
YCL030C(HIS4)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B08820(NCAS0B08820)
NDI: 
NDAI_0A00450(NDAI0A00450)
TPF: 
TPHA_0E03690(TPHA0E03690)
TDL: 
TDEL_0C06570(TDEL0C06570)
KAF: 
KAFR_0D00420(KAFR0D00420)
DHA: 
PIC: 
PGU: 
LEL: 
CAL: 
CTP: 
CDU: 
COT: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
MGR: 
FGR: 
NHE: 
TRE: 
VAL: 
SSL: 
BFU: 
ANI: 
AFM: 
AOR: 
AOR_1_840154(AO090003000477)
ANG: 
ANI_1_1704014(An01g12570)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
ZTR: 
TML: 
CNE: 
CNB: 
CGI: 
LBC: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
MBR: 
ACAN: 
PTI: 
TPS: 
PIF: 
EHX: 
GTT: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7049842
  Authors
Donahue TF, Farabaugh PJ, Fink GR
  Title
The nucleotide sequence of the HIS4 region of yeast.
  Journal
Gene 18:47-59 (1982)

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