KEGG   ORTHOLOGY: K14613Help
Entry
K14613                      KO                                     

Name
SLC46A1_3
Definition
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3
Disease
H01252  
Hereditary folate malabsorption (HFM)
Brite
Transporters [BR:ko02000]
 Solute Carrier Family (SLC)
  SLC46: Folate transporter family
   K14613  SLC46A1_3; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3
 Major Facilitator Superfamily (MFS)
  Organic acid transporters
   Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family
    K14613  SLC46A1_3; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3
BRITE hierarchy
Other DBs
Genes
HSA: 
113235(SLC46A1) 283537(SLC46A3)
PTR: 
454527(SLC46A1) 467249(SLC46A3)
PPS: 
100974524(SLC46A1) 100976250(SLC46A3)
GGO: 
101124330(SLC46A1) 101137178(SLC46A3)
PON: 
100172387(SLC46A3) 100440042(SLC46A1)
NLE: 
100592790(SLC46A3) 100599656(SLC46A1)
MCC: 
708727(SLC46A1) 712056(SLC46A3)
MCF: 
102116577(SLC46A3) 102128999(SLC46A1)
CJC: 
100411886(SLC46A1) 100414394(SLC46A3)
MMU: 
52466(Slc46a1) 71706(Slc46a3)
RNO: 
288454(Slc46a3) 303333(Slc46a1)
CGE: 
100756499(Slc46a3) 100757832(Slc46a1)
NGI: 
103724487(Slc46a1) 103727230(Slc46a3)
HGL: 
101706680(Slc46a1) 101710244(Slc46a3)
OCU: 
100009317(SLC46A1) 100343853(SLC46A3)
TUP: 
102474231(SLC46A3) 102487532(SLC46A1)
CFA: 
477324(SLC46A3) 491166(SLC46A1)
AML: 
100468045(SLC46A1) 100468808(SLC46A3)
UMR: 
103664322(SLC46A3) 103667230(SLC46A1)
FCA: 
101088541(SLC46A3) 101100096(SLC46A1)
PTG: 
102952124(SLC46A1) 102963702(SLC46A3)
BTA: 
511097(SLC46A1) 781117(SLC46A3)
BOM: 
102271829(SLC46A3) 102275758(SLC46A1)
PHD: 
102320978(SLC46A1) 102325853(SLC46A3)
CHX: 
102187500(SLC46A3) 102191550(SLC46A1)
OAS: 
101113342(SLC46A3) 101119738(SLC46A1)
SSC: 
100154155(SLC46A3) 100624611 100628018(SLC46A1)
CFR: 
102520521(SLC46A1) 102522706(SLC46A3)
BACU: 
103001026(SLC46A1) 103015319(SLC46A3)
LVE: 
103077796(SLC46A1) 103079197(SLC46A3)
ECB: 
100062949(SLC46A3) 100072047(SLC46A1)
MYB: 
102251643(SLC46A1) 102261323(SLC46A3)
MYD: 
102762830(SLC46A1) 102773377(SLC46A3)
PALE: 
102883186(SLC46A3) 102893216(SLC46A1)
MDO: 
100024595(SLC46A1) 100025451(SLC46A3)
SHR: 
100929844(SLC46A1) 100930692(SLC46A3)
OAA: 
100075532(SLC46A1) 100090766(SLC46A3)
GGA: 
417569(SLC46A1) 418924(SLC46A3)
MGP: 
APLA: 
101795521(SLC46A3) 101800835(SLC46A1)
TGU: 
100229183(SLC46A3) 100230017(SLC46A1)
FAB: 
101805768(SLC46A3) 101822270(SLC46A1)
PHI: 
102108555(SLC46A3) 102112748(SLC46A1)
FPG: 
101917306(SLC46A1) 101922175(SLC46A3)
FCH: 
102058520(SLC46A3) 102060198(SLC46A1)
CLV: 
102093730(SLC46A3) 102094714(SLC46A1)
ASN: 
102369417(SLC46A1) 102370892(SLC46A3)
AMJ: 
102564197(SLC46A3) 102576403(SLC46A1)
PSS: 
102452880(SLC46A1) 102457427(SLC46A3)
CMY: 
102929608(SLC46A3) 102943040(SLC46A1)
ACS: 
100561301(slc46a3) 100564942(slc46a1)
PBI: 
XLA: 
446819(slc46a1)
XTR: 
100145771(slc46a1) 100492828(slc46a3)
DRE: 
393255(slc46a1) 556497
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103180585(slc46a1) 103181790 103183243(slc46a3)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
100578557 552239(GB13859) 727496(GB16239)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_Y4C6B.5(Y4C6B.5)
CBR: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
TAD: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Zhao R, Matherly LH, Goldman ID
  Title
Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.
  Journal
Expert Rev Mol Med 11:e4 (2009)
Reference
  Authors
Nakai Y, Inoue K, Abe N, Hatakeyama M, Ohta KY, Otagiri M, Hayashi Y, Yuasa H
  Title
Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter.
  Journal
J Pharmacol Exp Ther 322:469-76 (2007)
  Sequence
[hsa:113235]

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