KEGG   ORTHOLOGY: K16058Help
Entry
K16058                      KO                                     

Name
ORAI3
Definition
calcium release-activated calcium channel protein 3
Pathway
Calcium signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K16058  ORAI3; calcium release-activated calcium channel protein 3
Transporters [BR:ko02000]
 Other Transporters
  Pores ion channels
   K16058  ORAI3; calcium release-activated calcium channel protein 3
BRITE hierarchy
Other DBs
Genes
HSA: 
93129(ORAI3)
PTR: 
454057(ORAI3)
PPS: 
100972631(ORAI3)
GGO: 
101147576(ORAI3)
PON: 
100460568(ORAI3)
MCC: 
712360(ORAI3)
MCF: 
102131759(ORAI3)
MMU: 
269999(Orai3)
RNO: 
309000(Orai3)
CGE: 
100753665(Orai3)
HGL: 
101705579(Orai3)
TUP: 
102493634(ORAI3)
CFA: 
607303(ORAI3)
AML: 
FCA: 
101091330(ORAI3)
PTG: 
102961617(ORAI3)
BTA: 
515971(ORAI3)
BOM: 
102275553(ORAI3)
PHD: 
102335581(ORAI3)
CHX: 
102175544(ORAI3)
SSC: 
100736565(ORAI3)
CFR: 
102516780(ORAI3)
BACU: 
102999297(ORAI3)
LVE: 
103080019(ORAI3)
ECB: 
100063559(ORAI3)
MYB: 
102252561(ORAI3)
MYD: 
102774046(ORAI3)
PALE: 
102884414(ORAI3)
MDO: 
100013345(ORAI3)
SHR: 
100929039(ORAI3)
OAA: 
100082960(ORAI3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I
  Title
Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states.
  Journal
Proc Natl Acad Sci U S A 108:17832-7 (2011)
Reference
  Authors
Mignen O, Thompson JL, Shuttleworth TJ
  Title
The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits.
  Journal
J Physiol 587:4181-97 (2009)
Reference
  Authors
Motiani RK, Zhang X, Harmon KE, Keller RS, Matrougui K, Bennett JA, Trebak M
  Title
Orai3 is an estrogen receptor alpha-regulated Ca(2)(+) channel that promotes tumorigenesis.
  Journal
FASEB J 27:63-75 (2013)

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