KEGG   ORTHOLOGY: K16060Help
Entry
K16060                      KO                                     

Name
BIRC2_3
Definition
baculoviral IAP repeat-containing protein 2/3
Pathway
Platinum drug resistance
NF-kappa B signaling pathway
Ubiquitin mediated proteolysis
Apoptosis
Apoptosis - multiple species
Necroptosis
Focal adhesion
NOD-like receptor signaling pathway
Toll and Imd signaling pathway
TNF signaling pathway
Toxoplasmosis
Pathways in cancer
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04668 TNF signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04215 Apoptosis - multiple species
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04217 Necroptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  Cellular community - eukaryotes
   04510 Focal adhesion
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 Organismal Systems
  Immune system
   04624 Toll and Imd signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04621 NOD-like receptor signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   05222 Small cell lung cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  Infectious diseases
   05145 Toxoplasmosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  Drug resistance
   01524 Platinum drug resistance
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
BRITE hierarchy
Genes
HSA: 
329(BIRC2) 330(BIRC3)
PTR: 
451507(BIRC3) 451508(BIRC2)
PPS: 
100970636(BIRC2) 100971429(BIRC3)
GGO: 
101126938(BIRC3) 101127675(BIRC2)
PON: 
100457249(BIRC3) 100457858(BIRC2)
NLE: 
100579740(BIRC3) 100580307(BIRC2)
MCC: 
702468(BIRC3) 702592(BIRC2)
MCF: 
102137780(BIRC3) 102138168(BIRC2)
CSAB: 
103248332(BIRC3) 103248333(BIRC2)
RRO: 
104674657(BIRC3) 104674658(BIRC2)
RBB: 
108514076(BIRC2) 108514077(BIRC3)
CJC: 
100394418(BIRC2) 100399118(BIRC3)
SBQ: 
101027816(BIRC2) 101043827(BIRC3)
MMU: 
11796(Birc3) 11797(Birc2)
RNO: 
60371(Birc2) 78971(Birc3)
CGE: 
100756596(Birc2) 100761700(Birc3)
NGI: 
HGL: 
101718804(Birc2) 101719143(Birc3)
CCAN: 
109689097(Birc2) 109689098(Birc3)
OCU: 
100338118(BIRC2) 100340120(BIRC3)
TUP: 
102493795(BIRC2) 102494213(BIRC3)
CFA: 
479464(BIRC2) 489433(BIRC3)
AML: 
UMR: 
FCA: 
101083444(BIRC3) 101101663(BIRC2)
PTG: 
102951731(BIRC3) 102972419(BIRC2)
AJU: 
BTA: 
514386(BIRC3) 539314(BIRC2)
BOM: 
102269806(BIRC3) 102286771(BIRC2)
BIU: 
PHD: 
102340588(BIRC2) 102340944(BIRC3)
CHX: 
102173485(BIRC2) 102173952(BIRC3)
OAS: 
101119930(BIRC2) 101120189(BIRC3)
SSC: 
CFR: 
102513751(BIRC3) 102513991(BIRC2)
CDK: 
105087177(BIRC2) 105087178(BIRC3)
BACU: 
103006934(BIRC3) 103007434(BIRC2)
LVE: 
103086871(BIRC3) 103087142(BIRC2)
ECB: 
100061273(BIRC2) 100068894(BIRC3)
EPZ: 
103552625(BIRC3) 103552627(BIRC2)
EAI: 
MYB: 
102240943(BIRC3) 102241248(BIRC2)
MYD: 
102771967(BIRC2) 102772449(BIRC3)
HAI: 
RSS: 
109435099(BIRC2) 109435100(BIRC3)
PALE: 
102884388(BIRC3) 102884651(BIRC2)
LAV: 
100659163(BIRC3) 100659446(BIRC2)
MDO: 
100010782(BIRC2)
SHR: 
OAA: 
100077243(BIRC2)
GGA: 
374012(BIRC2)
MGP: 
100543708(BIRC2)
CJO: 
107308397(BIRC2)
APLA: 
101793263(BIRC2)
ACYG: 
106034170(BIRC2)
TGU: 
100225317(BIRC2)
GFR: 
FAB: 
101821374(BIRC2)
PHI: 
102110239(BIRC2)
CCW: 
FPG: 
101924079(BIRC2)
FCH: 
102051620(BIRC2)
CLV: 
102090342(BIRC2)
AAM: 
106495530(BIRC2)
ASN: 
AMJ: 
102562735(BIRC2)
PSS: 
102448753(BIRC2)
CMY: 
CPIC: 
ACS: 
100554030(birc2)
PBI: 
103052845(BIRC2)
GJA: 
XLA: 
100036859(birc2.S) 446568(birc2.L)
XTR: 
448041(birc2)
NPR: 
DRE: 
373107(birc2)
SRX: 
SANH: 
SGH: 
IPU: 
100304597(birc2)
TRU: 
101075537(birc2)
TNG: 
LCO: 
104934542(birc2)
NCC: 
104964663(birc2)
MZE: 
101484124(birc2)
OLA: 
XMA: 
102228638(birc2)
CSEM: 
103395117(birc2)
LCF: 
SASA: 
ELS: 
105006427(birc2)
SFM: 
LCM: 
102364182(BIRC2)
CMK: 
103177430(birc2)
BFO: 
CIN: 
778881(zf(ring)-14)
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD25587(Dsim_GD25587)
DWI: 
DYA: 
Dyak_GE14118(Dyak_Iap2)
DGR: 
DMO: 
DVI: 
MDE: 
AAG: 
CQU: 
AME: 
413374(Iap2)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
NVI: 
TCA: 
663905(Tiap2)
DPA: 
NVL: 
BMOR: 
100529214(iap2)
DPL: 
PXY: 
API: 
DNX: 
PHU: 
DPX: 
ISC: 
LGI: 
CRG: 
OBI: 
LAK: 
NVE: 
ADF: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8643514
  Authors
Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL
  Title
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
  Journal
Proc Natl Acad Sci U S A 93:4974-8 (1996)
DOI:10.1073/pnas.93.10.4974
  Sequence
[hsa:329 330]
Reference
  Authors
Dubrez-Daloz L, Dupoux A, Cartier J
  Title
IAPs: more than just inhibitors of apoptosis proteins.
  Journal
Cell Cycle 7:1036-46 (2008)
DOI:10.4161/cc.7.8.5783

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