KEGG   ORTHOLOGY: K16195Help
Entry
K16195                      KO                                     

Name
EIF2AK2
Definition
eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
Pathway
Protein processing in endoplasmic reticulum
Necroptosis
Hepatitis C
Measles
Influenza A
Human papillomavirus infection
Kaposi's sarcoma-associated herpesvirus infection
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
  Infectious diseases
   05162 Measles
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05164 Influenza A
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05160 Hepatitis C
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05168 Herpes simplex infection
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05169 Epstein-Barr virus infection
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
   05165 Human papillomavirus infection
    K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Other group
  PEK family [OT]
   K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5610(EIF2AK2)
PTR: 
459155(EIF2AK2)
PPS: 
100982543(EIF2AK2)
GGO: 
101133221(EIF2AK2)
PON: 
100173054(EIF2AK2)
NLE: 
100579484(EIF2AK2)
MCC: 
708912(EIF2AK2)
MCF: 
102124745(EIF2AK2)
CSAB: 
103220482(EIF2AK2)
RRO: 
104669977(EIF2AK2)
CJC: 
100399251(EIF2AK2)
SBQ: 
101053943(EIF2AK2)
MMU: 
19106(Eif2ak2)
RNO: 
54287(Eif2ak2)
CGE: 
100757909(Eif2ak2)
NGI: 
103725269(Eif2ak2)
HGL: 
101724844(Eif2ak2)
CCAN: 
109688641(Eif2ak2)
OCU: 
100009013(EIF2AK2)
TUP: 
102469861(EIF2AK2)
CFA: 
611397(EIF2AK2)
AML: 
100469151(EIF2AK2)
UMR: 
103671577(EIF2AK2)
FCA: 
101082744(EIF2AK2)
PTG: 
102951575(EIF2AK2)
AJU: 
106978970(EIF2AK2)
BTA: 
347700(EIF2AK2)
BOM: 
102281444(EIF2AK2)
BIU: 
109565977(EIF2AK2)
PHD: 
102322134(EIF2AK2)
CHX: 
102171521(EIF2AK2)
OAS: 
101121673(EIF2AK2)
SSC: 
397588(EIF2AK2)
CFR: 
102517994(EIF2AK2)
BACU: 
103006520(EIF2AK2)
LVE: 
103075964(EIF2AK2)
ECB: 
100147679(EIF2AK2)
MYB: 
HAI: 
109385455(EIF2AK2)
RSS: 
109452817(EIF2AK2)
PALE: 
102890643(EIF2AK2)
LAV: 
100665908(EIF2AK2)
MDO: 
103106286(EIF2AK2)
SHR: 
100931721(EIF2AK2)
OAA: 
100077821(EIF2AK2)
GGA: 
395147(EIF2AK2)
MGP: 
CJO: 
107311230(EIF2AK2)
APLA: 
101798516(EIF2AK2)
TGU: 
100223594(EIF2AK2)
GFR: 
102039637(EIF2AK2)
FAB: 
101807308(EIF2AK2)
PHI: 
102111278(EIF2AK2)
CCW: 
104684377(EIF2AK2)
FPG: 
101910588(EIF2AK2)
FCH: 
102051537(EIF2AK2)
CLV: 
102085389(EIF2AK2)
AAM: 
106485536(EIF2AK2)
ASN: 
102379754(EIF2AK2)
AMJ: 
102558195(EIF2AK2)
PSS: 
102449543(EIF2AK2)
CMY: 
102934103(EIF2AK2)
CPIC: 
101940470(EIF2AK2)
ACS: 
100561872(eif2ak2)
PBI: 
GJA: 
XLA: 
XTR: 
100141483(pkr3) 779992(eif2ak2)
DRE: 
100001092(eif2ak2) 503703(pkz)
IPU: 
108263213(eif2ak2)
TRU: 
100144316(pkr1) 100144317(pkr2)
LCO: 
MZE: 
OLA: 
XMA: 
CSEM: 
103387634(eif2ak2)
SASA: 
LCM: 
102365233(EIF2AK2)
CMK: 
103187174(eif2ak2)
POP: 
ZTR: 
DPP: 
PTI: 
FCY: 
TPS: 
SPAR: 
GTT: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1695551
  Authors
Meurs E, Chong K, Galabru J, Thomas NS, Kerr IM, Williams BR, Hovanessian AG
  Title
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.
  Journal
Cell 62:379-90 (1990)
DOI:10.1016/0092-8674(90)90374-N
  Sequence
[hsa:5610]

DBGET integrated database retrieval system