KEGG   ORTHOLOGY: K16332Help
Entry
K16332                      KO                                     

Name
RBL2
Definition
retinoblastoma-like protein 2
Pathway
FoxO signaling pathway
Cell cycle
PI3K-Akt signaling pathway
Cellular senescence
Human papillomavirus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    K16332  RBL2; retinoblastoma-like protein 2
   04151 PI3K-Akt signaling pathway
    K16332  RBL2; retinoblastoma-like protein 2
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K16332  RBL2; retinoblastoma-like protein 2
   04218 Cellular senescence
    K16332  RBL2; retinoblastoma-like protein 2
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K16332  RBL2; retinoblastoma-like protein 2
  Infectious diseases
   05165 Human papillomavirus infection
    K16332  RBL2; retinoblastoma-like protein 2
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Other transcription factors
   Pocket domain Rb
    K16332  RBL2; retinoblastoma-like protein 2
BRITE hierarchy
Genes
HSA: 
5934(RBL2)
PTR: 
467978(RBL2)
PPS: 
100978830(RBL2)
GGO: 
101138930(RBL2)
PON: 
100444180(RBL2)
NLE: 
100595276(RBL2)
MCC: 
696992(RBL2)
MCF: 
102118320(RBL2)
CSAB: 
103232914(RBL2)
RRO: 
104658250(RBL2)
RBB: 
108531271(RBL2)
CJC: 
100410298(RBL2)
SBQ: 
101038159(RBL2)
MMU: 
19651(Rbl2)
RNO: 
81758(Rbl2)
CGE: 
100770221(Rbl2)
NGI: 
103731674(Rbl2)
HGL: 
101701252(Rbl2)
CCAN: 
OCU: 
100339977(RBL2)
TUP: 
102476721(RBL2)
CFA: 
478127(RBL2)
AML: 
100463875(RBL2)
UMR: 
103673796(RBL2)
ORO: 
101380168(RBL2)
FCA: 
101097858(RBL2)
PTG: 
102970305(RBL2)
AJU: 
106984720(RBL2)
BTA: 
533294(RBL2)
BOM: 
102271403(RBL2)
BIU: 
109572446(RBL2)
PHD: 
102327985(RBL2)
CHX: 
102181890(RBL2)
OAS: 
101114800(RBL2)
SSC: 
100627715(RBL2)
CFR: 
102524019(RBL2)
CDK: 
105097515(RBL2)
BACU: 
103018620(RBL2)
LVE: 
103074426(RBL2)
ECB: 
100060431(RBL2)
EPZ: 
103546526(RBL2)
EAI: 
106822536(RBL2)
MYB: 
102251179(RBL2)
MYD: 
102761562(RBL2)
HAI: 
109383411(RBL2)
RSS: 
109447710(RBL2)
PALE: 
102882545(RBL2)
LAV: 
100660308(RBL2)
TMU: 
MDO: 
100019136(RBL2)
SHR: 
100933451(RBL2)
OAA: 
100091282(RBL2)
GGA: 
425111(RBL2)
MGP: 
100547227(RBL2)
CJO: 
107319080(RBL2)
APLA: 
101789469(RBL2)
ACYG: 
106045264(RBL2)
TGU: 
100230395(RBL2)
GFR: 
102044028(RBL2)
FAB: 
101806783(RBL2)
PHI: 
102106505(RBL2)
PMAJ: 
107209759(RBL2)
CCW: 
104687468(RBL2)
FPG: 
101910475(RBL2)
FCH: 
102056460(RBL2)
CLV: 
102098411(RBL2)
EGZ: 
104125194(RBL2)
AAM: 
106483200(RBL2)
ASN: 
102372889(RBL2)
AMJ: 
102575184(RBL2)
PSS: 
102445416(RBL2)
CMY: 
102947067(RBL2)
CPIC: 
101945444(RBL2)
ACS: 
100556593(rbl2)
PVT: 
110082483(RBL2)
PBI: 
103053051(RBL2)
GJA: 
107119664(RBL2)
XLA: 
108714013(rbl2.L)
XTR: 
100490373(rbl2)
NPR: 
108789594(RBL2)
DRE: 
100331892(rbl2)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108275039(rbl2)
AMEX: 
103033933(rbl2)
TRU: 
TNG: 
LCO: 
MZE: 
XMA: 
PRET: 
NFU: 
107389125(rbl2)
CSEM: 
103379042(rbl2)
LCF: 
BPEC: 
SASA: 
ELS: 
SFM: 
108932983(rbl2)
LCM: 
102352332(RBL2)
CMK: 
103176093(rbl2)
SPU: 
APLC: 
ISC: 
OBI: 
EPA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8253384
  Authors
Hannon GJ, Demetrick D, Beach D
  Title
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.
  Journal
Genes Dev 7:2378-91 (1993)
DOI:10.1101/gad.7.12a.2378
  Sequence
[hsa:5934]
Reference
PMID:9192872
  Authors
Hurford RK Jr, Cobrinik D, Lee MH, Dyson N
  Title
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
  Journal
Genes Dev 11:1447-63 (1997)
DOI:10.1101/gad.11.11.1447
  Sequence
[mmu:19651]
Reference
  Authors
Claudio PP, Tonini T, Giordano A
  Title
The retinoblastoma family: twins or distant cousins?
  Journal
Genome Biol 3:reviews3012 (2002)
DOI:10.1186/gb-2002-3-9-reviews3012
  Sequence
[hsa:5934]

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