KEGG   ORTHOLOGY: K16343Help
Entry
K16343                      KO                                     

Name
PLA2G6, IPLA2
Definition
calcium-independent phospholipase A2 [EC:3.1.1.4]
Pathway
Glycerophospholipid metabolism
Ether lipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
alpha-Linolenic acid metabolism
Ras signaling pathway
Vascular smooth muscle contraction
Inflammatory mediator regulation of TRP channels
Disease
H00057  
Parkinson's disease (PD)
H00833  
Neurodegeneration with brain iron accumulation (NBIA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00564 Glycerophospholipid metabolism
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
   00565 Ether lipid metabolism
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
   00590 Arachidonic acid metabolism
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
   00591 Linoleic acid metabolism
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
   00592 alpha-Linolenic acid metabolism
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
 Organismal Systems
  Circulatory system
   04270 Vascular smooth muscle contraction
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2
BRITE hierarchy
Other DBs
Genes
HSA: 
8398(PLA2G6)
PTR: 
470208(PLA2G6)
PPS: 
100973899(PLA2G6)
GGO: 
101154603(PLA2G6)
PON: 
100445065(PLA2G6)
NLE: 
100605211(PLA2G6)
MCC: 
700184(PLA2G6)
MCF: 
CJC: 
100415535(PLA2G6)
MMU: 
53357(Pla2g6)
RNO: 
360426(Pla2g6)
CGE: 
100751421(Pla2g6)
NGI: 
103748592(Pla2g6)
HGL: 
101710669(Pla2g6)
OCU: 
100008961(PLA2G6)
TUP: 
102488703(PLA2G6)
CFA: 
481256(PLA2G6)
AML: 
UMR: 
103676531(PLA2G6)
FCA: 
101095350(PLA2G6)
PTG: 
102968751(PLA2G6)
BTA: 
535381(PLA2G6)
BOM: 
102285524(PLA2G6)
PHD: 
102337652(PLA2G6)
CHX: 
102182111(PLA2G6)
OAS: 
101103799(PLA2G6)
SSC: 
100514711(PLA2G6)
CFR: 
102514758(PLA2G6)
BACU: 
103005121(PLA2G6)
LVE: 
103091644(PLA2G6)
ECB: 
100055064(PLA2G6)
MYB: 
102258983(PLA2G6)
MYD: 
102763469(PLA2G6)
PALE: 
102880597(PLA2G6)
MDO: 
100016178(PLA2G6)
SHR: 
100916580(PLA2G6)
OAA: 
100090638(PLA2G6)
GGA: 
418028(PLA2G6)
MGP: 
100549498(PLA2G6)
APLA: 
101797588(PLA2G6)
TGU: 
100222459(PLA2G6)
FAB: 
101818570(PLA2G6)
PHI: 
102111464(PLA2G6)
FPG: 
101918608(PLA2G6)
FCH: 
102054654(PLA2G6)
CLV: 
102095923(PLA2G6)
ASN: 
102376808(PLA2G6)
AMJ: 
102571693(PLA2G6)
PSS: 
102443808(PLA2G6)
CMY: 
102932915(PLA2G6)
ACS: 
100559750(pla2g6)
PBI: 
103062068(PLA2G6)
XLA: 
446689(pla2g6)
DRE: 
406370(pla2g6)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102355713(PLA2G6)
CMK: 
103172053(pla2g6)
CIN: 
SPU: 
DME: 
Dmel_CG6718(iPLA2-VIA)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
410570(GB19826)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_F47A4.5(F47A4.5) CELE_W07A8.2(W07A8.2)
CBR: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Schaloske RH, Dennis EA
  Title
The phospholipase A2 superfamily and its group numbering system.
  Journal
Biochim Biophys Acta 1761:1246-59 (2006)
Reference
  Authors
Lv Z, Guo J, Sun Q, Li K, Yu R, Tian J, Yan X, Tang B
  Title
Association between PLA2G6 gene polymorphisms and Parkinson's disease in the Chinese Han population.
  Journal
Parkinsonism Relat Disord 18:641-4 (2012)

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