KEGG   ORTHOLOGY: K18113
Entry
K18113            Tight     KO                                     
Symbol
MDS
Name
miltiradiene synthase / copalyl diphosphate synthase [EC:4.2.3.131 5.5.1.12]
Pathway
map00904  Diterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R06298  (+)-copalyl-diphosphate lyase (decyclizing)
R10585  (+)-copaly-diphosphate diphosphate-lyase (cyclizing, miltiradiene-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K18113  MDS; miltiradiene synthase / copalyl diphosphate synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.131  miltiradiene synthase
     K18113  MDS; miltiradiene synthase / copalyl diphosphate synthase
 5. Isomerases
  5.5  Intramolecular lyases
   5.5.1  Intramolecular lyases (only sub-subclass identified to date)
    5.5.1.12  copalyl diphosphate synthase
     K18113  MDS; miltiradiene synthase / copalyl diphosphate synthase
Other DBs
GO: 0050559
Genes
SMO: SELMODRAFT_450918
Reference
PMID:22027823
  Authors
Sugai Y, Ueno Y, Hayashi K, Oogami S, Toyomasu T, Matsumoto S, Natsume M, Nozaki H, Kawaide H
  Title
Enzymatic (13)C labeling and multidimensional NMR analysis of miltiradiene synthesized by bifunctional diterpene cyclase in Selaginella moellendorffii.
  Journal
J Biol Chem 286:42840-7 (2011)
DOI:10.1074/jbc.M111.302703
  Sequence
[smo:SELMODRAFT_450918]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (2)   
   KEGG GENES (1)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (18)   

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