KEGG   ORTHOLOGY: K18315
Entry
K18315                      KO                                     
Symbol
cpmC, carC
Name
(5R)-carbapenem-3-carboxylate synthase [EC:1.14.20.3]
Pathway
map00332  Carbapenem biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map02024  Quorum sensing
Module
M00675  Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate
Reaction
R10415  (3S,5S)-carbapenam-3-carboxylate,2-oxoglutarate:oxygen oxidoreductase (dehydrating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00332 Carbapenem biosynthesis
    K18315  cpmC, carC; (5R)-carbapenem-3-carboxylate synthase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K18315  cpmC, carC; (5R)-carbapenem-3-carboxylate synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.20  With 2-oxoglutarate as one donor, and the other dehydrogenated
    1.14.20.3  (5R)-carbapenem-3-carboxylate synthase
     K18315  cpmC, carC; (5R)-carbapenem-3-carboxylate synthase
Other DBs
COG: COG2175
Genes
PROD: PCO85_15480
SERA: Ser39006_009930
SERQ: CWC46_09925
PARI: I2D83_01760
PPAV: LOZ86_02770
PCAC: OI450_17085
PACB: M9782_00165
DZE: Dd1591_0211
DAQ: DAQ1742_04176(cpmC)
PAO: Pat9b_5315
PLU: plu0184(cpmC)
PLUM: A4R40_00890
PTT: VY86_09605
PRG: RB151_027400(carC)
PRJ: NCTC6933_00419
VSR: Vspart_02937
VRU: RND59_08410
BGP: BGL_2c27600
BPLA: bpln_2g27640
 » show all
Reference
PMID:12848554
  Authors
Stapon A, Li R, Townsend CA
  Title
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.
  Journal
J Am Chem Soc 125:8486-93 (2003)
DOI:10.1021/ja034248a

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (20)   
   KEGG GENES (19)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (36)   

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