KEGG   Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_02705
Entry
KPN_02705         CDS       T00566                                 
Symbol
folC
Name
(GenBank) dihydrofolate:folylpolyglutamate synthetase; dihydrofolate synthetase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
kpn  Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00790  Folate biosynthesis
kpn01100  Metabolic pathways
kpn01240  Biosynthesis of cofactors
Module
kpn_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:kpn00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    KPN_02705 (folC)
Enzymes [BR:kpn01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     KPN_02705 (folC)
    6.3.2.17  tetrahydrofolate synthase
     KPN_02705 (folC)
SSDB
Motif
Pfam: Mur_ligase_C Mur_ligase_M
Other DBs
NCBI-ProteinID: ABR78122
UniProt: A6TC01
Position
complement(2974332..2975600)
AA seq 422 aa
MEKDPIPQATSPLATWLSYLEHLHNKTIDLGLARVSEVAGQMDIVKPAPFVFTVAGTNGK
GTTCRTLETILMAAGYKVGVYSSPHLVRYTERVRIQGAELPEAAHTASFAEIEAARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRAGKPAVVGEPDMPLTIAEVASEKGALLQRRGVDWRYEVEGEKWSFRD
TAGALSHLPLPQVPLPNAATAVAALRASGLAVDDAILRAGIRDAMLPGRFQIISDAPRVI
LDVAHNPHAAAYLAGRLKTLAKTGRVLAVIGMLHDKDIAGTLANLAPEVDAWYCAPLEGP
RGATAEQLVEHLRCGTVYSSVAQAWRAAMADAKVEDTVLVCGSFHTVAQVMEEIDAGRIG
GE
NT seq 1269 nt   +upstreamnt  +downstreamnt
atggaaaaagatcctattcctcaggccacgtcgcccctggctacgtggctttcttatctg
gaacatctgcacaataaaaccatcgaccttgggctggcgcgcgtcagcgaggtcgccggg
cagatggatatcgttaaaccggcgccgttcgtttttaccgtcgcgggcaccaatggcaaa
ggcaccacctgccgcacgctggaaaccatcctgatggcggccggttataaagtgggggtc
tacagctctccgcatctggtgcgctacaccgaacgcgtgcgcattcagggggctgaactg
ccggaggcggcgcatacggcttcgtttgctgaaatcgaagcggcgcggggtgacatctcg
ctgacctattttgaatacggcacgctctcggcgctgtggctgtttaagcaggcgcagctg
gatgtggtgatccttgaggtcgggctcggcgggcgtctcgacgctaccaacatcgttgat
gccgacgtcgcagtggtcaccagcatcgccctcgatcataccgactggctggggccggat
cgcgaaagtatcggccgggaaaaagcgggcatctttcgcgccggtaaaccggcggtggtg
ggggagccggatatgccgctcaccatcgcggaagtggctagcgagaagggcgcgctgctc
cagcgccgcggcgtcgactggcgctatgaggtggaaggcgaaaagtggtccttccgcgat
acggcaggggcgttaagccacctgcctctgcctcaggtgccgttgccgaatgcggcgacg
gccgtggcggcgctgcgcgccagcgggcttgccgtggatgacgctatcctgcgcgcaggg
atccgcgatgcgatgctcccgggacgctttcagataattagcgacgccccgcgagtgatc
ctcgatgtggcgcacaacccgcacgcggcggcctatctcgccgggcgtctcaaaacgtta
gcgaaaacgggacgcgtgctggcggttattggtatgctgcatgataaggatatcgccggc
acgttggccaatctggccccggaagtcgatgcctggtactgcgcgccgctggaaggcccg
cgcggcgcgacggcagagcagctggtggaacatttgcgctgcggtacagtctatagcagc
gtggcgcaggcgtggcgtgcggccatggctgacgctaaagtggaagataccgtgctggtg
tgtggttcgtttcacaccgtagcgcaggttatggaagagatagacgcggggagaatcggt
ggcgagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (36)   

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