KEGG   Klebsiella pneumoniae 32192: KU54_022300
Entry
KU54_022300       CDS       T03746                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
kpne  Klebsiella pneumoniae 32192
Pathway
kpne00010  Glycolysis / Gluconeogenesis
kpne00020  Citrate cycle (TCA cycle)
kpne00620  Pyruvate metabolism
kpne00785  Lipoic acid metabolism
kpne01100  Metabolic pathways
kpne01110  Biosynthesis of secondary metabolites
kpne01120  Microbial metabolism in diverse environments
kpne01200  Carbon metabolism
kpne01210  2-Oxocarboxylic acid metabolism
Module
kpne_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:kpne00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    KU54_022300 (aceE)
   00020 Citrate cycle (TCA cycle)
    KU54_022300 (aceE)
   00620 Pyruvate metabolism
    KU54_022300 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    KU54_022300 (aceE)
Enzymes [BR:kpne01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     KU54_022300 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C Viral_DNA_bp
Other DBs
NCBI-ProteinID: AJB59376
UniProt: W9BBR8
Position
complement(4407896..4410559)
AA seq 887 aa
MSERLHNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASAGNY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASYQSSATFYEV
CFNHFFRARTEKDGGDLVYFQGHISPGVYARAFLEGRLTEEQMDNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLEHRGLKDTSEQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGQPTVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYVTFPEGSEEHTYLHAQRQKLNGYLPTRQPKFTEKLELPTLA
DFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLVRMYGEAQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgtcagaacgtttacacaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactc
ctttctgaagcccgtaaaggcggagtgaaggttgctgcaggcgcttccgccggcaactac
gtcaacactattgccgttgaagatgagccggaatacccgggcaatctggatctggaacgt
cgcattcgttctgcgattcgctggaacgccatcatgaccgttctgcgcgcgtcgaaaaaa
gatctcgaactgggcggccacatggcgtcctatcagtcttccgcgaccttctacgaagtc
tgcttcaaccacttcttccgtgcgcgcactgagaaagatggcggcgatctggtgtacttc
cagggtcacatctctccgggcgtatatgcacgtgcgttcctggaaggccgtctgaccgaa
gagcagatggacaacttccgtcaggaagttcacggcaagggcctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtatccatggggctggggccgttg
ggcgctatctatcaggccaaattcctgaaatatctggaacaccgcggtctgaaagacacc
tccgaacaaaccgtttacgccttcctgggcgacggcgagatggatgagccggaatcaaaa
ggcgctatcaccatcgccacccgtgaaaaactggacaacctggtcttcgtcatcaactgc
aacctgcagcgtctggacggcccggtcaccggtaacggcaaaatcattaacgaactggaa
ggcatcttcggtggtgctggctggaacgttatcaaggttatctggggcggccgttgggat
gagctgctgcgtaaagacaccagcggtaagctgattcagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgttcgtgagcacttcttcggc
aaatatccggaaaccgctgccctggtcgctgactggactgacgagcagatctgggctctg
aaccgcggtggtcacgatccgaagaaagtctacgctgcattgaagaaagcgcaggagacc
aaaggtcagccgaccgtgatcctggcgcataccattaaaggttatggtatgggcgatacc
gctgaaggtaagaacatcgcgcaccaggttaagaaaatgaacatggacggtgttcgctac
gtccgcgatcgtttcaatgtgccggtggcggatgccgatctcgaaaaactgccgtacgta
accttcccggaaggttccgaagagcacacttacctgcacgctcagcgtcagaagctgaac
ggctatctgccgactcgtcagccgaagttcactgagaaactcgagctgccgaccctggcc
gacttcagcgcgctgctggaagagcaaaacaaagaaatctctaccactatcgctttcgtt
cgcgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggtgccgatcatc
gccgacgaagcgcgtaccttcggtatggaaggtctgttccgtcagatcggtatttacagc
ccgaacggccagcagtataccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaagggatcaacgagctgggcgcaggcgcatcctggctg
gctgctgcgacctcttacagcaccaacaacctgccgatgatcccgttctacatctactac
tcgatgttcggcttccagcgtatcggcgatctgtgctgggcggctggcgatcagcaggct
cgcggcttcctgattggcgggacttccggtcgtactaccctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcgtacgcctatgaagtggctgtcatcatgcatgatggtctggtccgtatgtacggc
gaagcgcaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gccatgccggaaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccatc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtgcgt
gaagcagcgcagatcctggcgaaagactacggcgtgggttccgacgtgtatagcgttacc
tccttcaccgaactggcgcgtgatggccaggattgcgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgtgccgtatatcgctcaggtaatgaacgacgctccggcagtggca
tccactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagtcgatgcttcctatgtggtcgtagcagcgctgggcgaactggctaaacgt
ggtgaaatcgataagaaagtggtggctgacgctatcgcgaaattcgacatcgatgcagaa
aaagttaacccgcgtctggcgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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