KEGG   Klebsiella pneumoniae Kp52.145: BN49_4260
Entry
BN49_4260         CDS       T05281                                 
Symbol
leuA2
Name
(GenBank) highly similar to 2-isopropylmalate synthase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T4L9)
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
kpnk  Klebsiella pneumoniae Kp52.145
Pathway
kpnk00290  Valine, leucine and isoleucine biosynthesis
kpnk00620  Pyruvate metabolism
kpnk01100  Metabolic pathways
kpnk01110  Biosynthesis of secondary metabolites
kpnk01210  2-Oxocarboxylic acid metabolism
kpnk01230  Biosynthesis of amino acids
Module
kpnk_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:kpnk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    BN49_4260 (leuA2)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    BN49_4260 (leuA2)
Enzymes [BR:kpnk01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     BN49_4260 (leuA2)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Trp_syntA
Other DBs
NCBI-ProteinID: CDO16009
Position
4524089..4525660
AA seq 523 aa
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEY
ANIISGLYDRVPNIDKAIISVHTHDDLGIAVGNALAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYQESDYNLDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFNVQSGSSDIATASIKLVCGDEIKT
EAANGNGPVDAIYQAINRVTDYNIELVKYGLSAKGHGKDALGQVDIVVDYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgagccagcaagtcattattttcgatacgaccttacgtgatggcgaacaagcgttacag
gcaagcctgagtgtcaaagagaagctgcagatcgcactggcccttgagcgaatgggggtc
gacgtaatggaagtcggtttcccggtatcctcgccgggcgattttgaatcggtgcaaacc
atcgcacgcaccattaaaaacagccgcgtgtgcgctctggcgcgctgcgttgagaaagat
atcgacgtggcggcggaatcgttaaaagtggccgaggctttccgtattcatacctttatt
gccacctcgccgatgcatatcgccaccaaactgcgcagtacgctggatgaggttattgag
cgcgcgatctatatggtgaagcgggcacgcaactacactgacgacgttgagttctcctgt
gaagacgccggccgtacgccgattgccgatctggctcgcgtcgtggaagcggcgatcaac
gccggcgccaccaccattaatatcccggataccgtcggctataccatgccgttcgaatat
gccaacatcatcagcggcctgtatgatcgcgtgccgaatatcgacaaagcaattatttcc
gtccacacccatgatgatctgggcatcgctgtcggtaacgccctcgccgcggtccacgcc
ggtgcgcgccaggtagaaggtgcgatgaacggtatcggcgaacgcgccggcaactgcgcg
ctggaagaagtgatcatggcgatcaaagtgcgcaaagacatcatgaacgtgcacaccaac
attaatcatcatgaaatctggcgcaccagccagaccgtcagccagatctgcaatatgccg
atcccggcgaacaaggccatcgtcggcaccggcgccttcgcccactcctccggcattcac
caggacggcgtgctgaagaaccgcgaaaactacgagatcatgaccccggaatctatcggc
ctgaaccaggtgcaattgaacctgacttcccgctccggccgcgcggcggtgaaacaccgg
atggaagagatgggctaccaggagagcgattacaacctggatcatctgtacgacgcattc
ctgaagctggcggacaaaaaaggccaggtcttcgattacgatctggaagcgctggccttt
atcaacaagcagcaggaagagccagagcatttccgcctggattacttcaacgtccaatcc
ggatccagcgatatcgccaccgcctcgatcaaactggtctgcggggatgagatcaaaacc
gaagccgccaacggcaacggtccggtcgatgctatctaccaggcgattaatcgcgtcacc
gactacaacattgaattagtgaagtatggcttaagcgcgaaaggccacggcaaagacgcc
ctgggccaggtggatatcgtcgttgactacaatggccgccgcttccatggcgttggtctg
gcaacggatatcgtagagtcgtcagccaaagcgatggttcacgtgctgaacaacatctgg
cgcgccgccgaagtcgaaaaagaattgcaacgcaaagctcagaataaagagaacaataag
gaaaccgtgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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