KEGG   Klebsiella pneumoniae subsp. pneumoniae KPNIH31: KPNIH31_26610
Entry
KPNIH31_26610     CDS       T03467                                 
Name
(GenBank) dihydrofolate reductase
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
kpy  Klebsiella pneumoniae subsp. pneumoniae KPNIH31
Pathway
kpy00670  One carbon pool by folate
kpy00790  Folate biosynthesis
kpy01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:kpy00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    KPNIH31_26610
   00670 One carbon pool by folate
    KPNIH31_26610
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:kpy01504]
    KPNIH31_26610
Enzymes [BR:kpy01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     KPNIH31_26610
Antimicrobial resistance genes [BR:kpy01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    KPNIH31_26610
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AIX87225
UniProt: A0A221KLI8
Position
pKPN-c22:51171..51644
AA seq 157 aa
MKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYA
VVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLSTIDI
EPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG
NT seq 474 nt   +upstreamnt  +downstreamnt
ttgaaagtatcattgatggctgcgaaagcgaaaaacggcgtgattggttgcggtccagac
ataccctggtccgcgaaaggggagcagctactttttaaagcattgacctacaatcagtgg
cttctggtgggtcgcaagacgtttgaatctatgggcgcactccccaataggaaatacgcg
gtcgttacccgctcaggttggacatcaaatgatgacaatgtagttgtatttcagtcaatc
gaagaggccatggacaggctagctgaattcaccggtcacgttatagtgtctggtggcgga
gaaatttaccgagaaacattacccatggcctctacgctccacttatcgacgatcgacatc
gagccagagggggatgttttcttcccgagtattccaaataccttcgaagttgtttttgag
caacactttacttcaaacattaactattgctatcaaatttggaaaaagggttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (27)   

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