KEGG   Loxodonta africana (African savanna elephant): 100656674
Entry
100656674         CDS       T04351                                 
Symbol
TEK
Name
(RefSeq) angiopoietin-1 receptor
  KO
K05121  endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04010  MAPK signaling pathway
lav04014  Ras signaling pathway
lav04015  Rap1 signaling pathway
lav04066  HIF-1 signaling pathway
lav04151  PI3K-Akt signaling pathway
lav05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100656674 (TEK)
   04014 Ras signaling pathway
    100656674 (TEK)
   04015 Rap1 signaling pathway
    100656674 (TEK)
   04066 HIF-1 signaling pathway
    100656674 (TEK)
   04151 PI3K-Akt signaling pathway
    100656674 (TEK)
 09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    100656674 (TEK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100656674 (TEK)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:lav04090]
    100656674 (TEK)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100656674 (TEK)
Protein kinases [BR:lav01001]
 Receptor tyrosine kinases (RTK)
  TIE family
   100656674 (TEK)
CD molecules [BR:lav04090]
 Proteins
  100656674 (TEK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ig_Tie2_1 Pkinase fn3 Pur_ac_phosph_N ig EGF_2 hEGF DL-JAG_EGF-like fn3_2 APH DUF4702 Haspin_kinase Pkinase_fungal
Other DBs
NCBI-GeneID: 100656674
NCBI-ProteinID: XP_023400978
Position
Unknown
AA seq 1058 aa
MDLILINSLPLVSDAETSLTCIASGWHPHEPITIGRDFEALMNQHQDPLEVTQDVTREWA
KKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISF
KKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPRAQPQDAGVYSARYIGGNLFTSAF
TRLIVRRCEAQKWGPECNRPCTDCVNNGVCHEDTGECICPPGFMGRTCEKACGLHTFGRT
CKEQCSGPEGCKSYVFCLPDPYGCSCATGWKGLLCNEGMPLMTPKIVDLPGHIEVNSGKF
NPICKASGWPLPANEEMTLVKPDGTVLHPKDFNHTDHLSVATFTIPRILPPDSGVWVCSV
NTVAGMVEEPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPFFGDGPIKSKKLLYKPV
NHYEAWRHIPVTSEIVTLNALEPRTEYELCVQLIRRGEGGEGHPGPVRRFTTASISLPPP
RGLSLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQMKSDQQNIKVPGNLTSVLLNNL
HPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITDSTAIISWAILDGY
SISSITIRYKVQGKNEDQHIDVKIKNTTITQYQLKGLEPETAYQVDIFAENNIGSSNPTF
SHELMTLAESQVGTNLGGGKMLLIAILGSAGMTCLTVLLTFLIMLQLKRANVQRRMAQAF
QNREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKD
GLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAP
HGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLA
ARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGV
LLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFA
QILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA
NT seq 3177 nt   +upstreamnt  +downstreamnt
atggacctgatcttgatcaattccctacctcttgtatctgatgctgaaacatccctcacc
tgcattgcttctgggtggcacccccatgagcccatcaccataggaagggactttgaagcc
ttaatgaaccagcaccaggatccactggaagttactcaagatgtgactagagaatgggct
aaaaaagttgtttggaagagggaaaaggctagtaaaatcaatggtgcttatttctgtgaa
gggcgagttcgaggagaggcaataaggatacggaccatgaagatgcggcaacaagcttcc
ttcctaccagctactttaactatgactgtggacaaaggagataatgtgaacatatctttc
aaaaaggtgttgattaaagaagaagatgcagtgatttacaaaaatggttccttcatccat
tcagtcccccggcacgaagtcccagatattttagaagtgcacctgccacgtgctcagccc
caggatgctggagtgtactcggccaggtacataggaggaaacctcttcacctcggccttc
accaggctgatagtccggagatgtgaagctcagaagtggggacctgaatgcaaccgtcct
tgcactgattgtgtgaacaatggtgtctgccatgaagacaccggagagtgcatttgccct
cctggatttatggggagaacatgcgagaaggcttgtgggctgcacacatttggtagaacc
tgtaaagaacaatgtagtggaccagagggatgcaagtcctacgtgttctgtctcccagac
ccatatgggtgttcctgtgccacaggctggaagggactgctgtgtaatgaaggtatgcca
ctgatgaccccaaaaatagtggatttgccaggtcacatagaagtaaacagtggtaaattt
aaccccatctgcaaagcctctggctggccgctacctgctaacgaagaaatgacactggtg
aagccggatgggacagtgctgcatccaaaagactttaaccacacggatcatctctcagtg
gccacattcaccatcccccggatcctgccccctgactcaggagtttgggtctgcagtgtg
aacacagtggctgggatggtagaagagcctttcaacatttctgttaaagttcttccaaag
cccctgaatgccccaaacgtgatcgacactggacataactttgctgtcatcaacatcagc
tctgagcctttctttggggatggaccaatcaagtccaagaagcttctttacaaacctgtt
aatcattacgaggcttggcggcatattccagtgacaagtgagattgttacactgaatgct
ttggaacctcgaacagaatatgagctctgcgtgcagctgatccggcgcggagagggcgga
gaagggcatcctggacccgtgagacggttcacaacagcttccatcagtctccctcctccg
agaggtctcagtctcctaccaaaaagtcagaccactctaaatttgacctggcaaccaata
ttcccaagctcagaagatgacttttatgttgaagttgagaggaggtctgtgcaaatgaaa
agtgaccagcaaaatattaaagtgcctggcaacttgacttcggtactgcttaacaattta
caccctagggagcagtatgtggtccgagccagagtcaacaccaaggcccaaggggaatgg
agtgaagatctcactgcctggacccttagtgacattcttcctcctcaaccagaaaacatc
aagatttccaatatcacagactccacggctattatctcttgggcaatattggatggctat
tctatttcttctattaccatccgttacaaggttcagggcaagaatgaggaccagcacatt
gatgtgaagatcaagaatacaaccatcacccagtaccagctcaaaggcctagaacctgaa
acagcttatcaggtggacatttttgcagagaacaacatagggtcaagcaaccccaccttt
tctcatgaactgatgacccttgcagaatctcaagtcggaacgaaccttggaggtgggaag
atgctgcttatagccatccttggctcagctggaatgacctgcctgacggtgctgttgacc
tttctgatcatgttgcaattgaagagggcaaatgtccaaaggagaatggcccaagccttc
caaaacagggaagaaccagctgtgcagttcaactcaggaactctggccctgaacaggaag
gccaaaaacaacccggatcctacaatttatccagtccttgactggaatgacatcaaattt
caagatgtgattggggaggggaattttggccaggttctgaaggcacgtatcaagaaggat
gggctacggatggacgctgccatcaagaggatgaaagaatatgcctccaaagatgatcac
agggacttcgcaggggaacttgaagttctttgtaaacttggacatcatccgaacatcatc
aatctcttgggagcatgtgaacatcgaggctacttgtacctggccatcgagtatgccccc
catggaaacctcctggacttcctgcgcaagagccgagtgctggagactgaccctgcattt
gccatcgccaacagcactgcttccacgctgtcctcccagcagcttcttcattttgcagca
gatgtagcccggggtatggactacctgagccaaaaacagtttattcacagagatctggct
gccaggaacattttagtcggtgaaaactatgtagccaaaatagctgattttggattgtcc
agaggtcaagaagtgtacgtgaaaaagacgatgggaaggctccctgtgcgctggatggcg
atcgagtcactgaattacagcgtatacacgaccaacagtgacgtttggtcctacggtgtg
ttactatgggagattgttagcttaggtggcacaccctattgtgggatgacgtgtgcagag
ctctatgagaagctgccccagggctacagactggagaagcccctaaactgtgatgacgag
gtgtatgacctaatgagacaatgctggcgagagaagccttatgagaggccatcatttgct
cagatattggtgtcattaaacaggatgctagaagaacgaaagacctatgtgaacactacg
ctttatgagaagttcacctatgcaggtatcgactgctctgctgaggaagcagcctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (41)   

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