KEGG T04351: 100664945

Loxodonta africana (African savanna elephant): 100664945

Entry

100664945         CDS       T04351

Symbol

RRM2

Name

(RefSeq) ribonucleoside-diphosphate reductase subunit M2

K10808

ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]

Organism

lav Loxodonta africana (African savanna elephant)

Pathway

lav00230

Purine metabolism

lav00240

Pyrimidine metabolism

lav00480

Glutathione metabolism

lav00983

Drug metabolism - other enzymes

lav01100

Metabolic pathways

lav01232

Nucleotide metabolism

lav04115

p53 signaling pathway

Module

lav_M00053

Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP

lav_M00938

Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Brite

KEGG Orthology (KO) [BR:lav00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100664945 (RRM2)
   00240 Pyrimidine metabolism
    100664945 (RRM2)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100664945 (RRM2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    100664945 (RRM2)
09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    100664945 (RRM2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:lav03400]
    100664945 (RRM2)
Enzymes [BR:lav01000]
1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     100664945 (RRM2)
DNA repair and recombination proteins [BR:lav03400]
Eukaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    100664945 (RRM2)

SSDB

Motif

Pfam:

Ribonuc_red_sm

Other DBs

NCBI-GeneID:

100664945

NCBI-ProteinID:

XP_003411931

UniProt:

G3SSS7

Position

Unknown

AA seq 386 aa
MLSVRVPLATIDQQQLRLSPMKGLTLADKENTPPSLSSARVLASKAARKIFQEPENTKVP
ASSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPEE
RYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTY
IKDSKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASI
FWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHKPSEQRVKEIIINAVRIEQEF
LTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKVFKVENPFDFMENISLEGKTNFFE
KRVGEYQRMGVMSSPTENSFTLDADF

NT seq 1161 nt +upstreamnt +downstreamnt
atgctgtcggtccgtgtcccgctcgccaccatcgaccagcagcagctccggctttctccc
atgaaggggctcaccctggcggacaaagagaacactcccccgtctctcagcagtgcccgc
gtcctggccagcaaggctgcgaggaagatcttccaggagccggagaacactaaggtacct
gcctccagcgtggaagatgaaccactgctgagagaaaatccccgccgctttgtcgtcttt
cctattgaataccatgatatttggcagatgtacaagaaagctgaggcttccttttggaca
gctgaggaggtggatctttccaaggacattcagcactgggaagccctgaagcctgaggag
agatattttatatcacacgttctggctttctttgcagcaagtgatggcatagtgaatgaa
aacctggtggagcgatttagccaagaagttcagattaccgaagcccgctgtttctatggc
ttccaaattgccatggaaaacatacattctgaaatgtatagtctccttattgacacttac
attaaagattccaaggaaagggagtttctcttcaacgccattgaaacgatgccttgtgta
aaaaagaaggcagattgggccttgcgttggattggggacaaagaagctacctatggagag
cgtgttgtagcctttgcagcagtagaagggatcttcttttctggttcttttgcatcgata
ttctggctcaagaaacgaggattaatgcctggcctcacgttctccaatgaacttattagc
agagatgagggtttacactgtgactttgcctgcctcatgttcaaacacctgctacacaaa
ccttcggagcaaagagtcaaagaaataattattaacgctgttaggatagaacaggagttc
cttaccgaggccttgcctgtgaagcttatcggaatgaattgtactttaatgaagcagtac
attgaattcgtggcggacagactaatgctggaactgggttttaacaaggtgttcaaagta
gagaatccatttgactttatggagaacatttcactggaagggaagactaacttcttcgag
aagagagtaggcgagtatcagagaatgggagtgatgtcgagcccaacagagaattctttt
accttggatgccgacttctga

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