| Entry |
|
|---|
| Name |
chloride peroxidase;
chloroperoxidase |
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| Class |
Oxidoreductases;
Acting on a peroxide as acceptor;
Peroxidases
 |
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| Sysname |
chloride:hydrogen-peroxide oxidoreductase |
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| Reaction(IUBMB) |
RH + HCl + H2O2 = RCl + 2 H2O [RN:R00052] |
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| Reaction(KEGG) |
R00052
 |
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| Substrate |
RH [CPD:C01371];
HCl [CPD:C01327];
H2O2 [CPD:C00027] |
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| Product |
RCl [CPD:C01334];
H2O [CPD:C00001] |
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| Cofactor |
Heme [CPD:C00032] |
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| Comment |
Brings about the chlorination of a range of organic molecules,
forming stable C-Cl bonds. Can also act on Br- and I-. Probably a
heme-thiolate protein (P-450). |
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| Orthology |
KO: K00433 chloride peroxidase |
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| Genes |
DHA: DEHA0A08558g
MGR: MGG_02210
TET: TTHERM_00089170
ENT: Ent638_1149
KPN: KPN_02451
KPE: KPK_1737
KPU: KP1_3653
CKO: CKO_04375
XCC: XCC2172(cpo)
XCB: XC_1946
XCV: XCV2196
XAC: XAC2035(cpo)
PAE: PA2717(cpo)
PAU: PA14_29020(cpo)
PPU: PP_4021(est)
PPF: Pput_1812
PSB: Psyr_4478
PFL: PFL_3458
PFO: Pfl01_2172 Pfl01_2461
PEN: PSEEN2814(cpo) PSEEN5395
PSA: PST_0170
ACB: A1S_1833
ABY: ABAYE1730(dch)
SDN: Sden_2086
HCH: HCH_03053
REU: Reut_B5209
REH: H16_A2213 H16_B1410 H16_B1943
RME: Rmet_5312
BPS: BPSS0444(cpo)
BPM: BURPS1710b_A1992(cpo)
BPL: BURPS1106A_A0603(cpoF)
BPD: BURPS668_A0694
BVI: Bcep1808_5649 Bcep1808_6373
BUR: Bcep18194_A4969 Bcep18194_C6615 Bcep18194_C6846 Bcep18194_C6920
Bcep18194_C7311 Bcep18194_C7313 Bcep18194_C7479 Bcep18194_C7536
BCN: Bcen_1450 Bcen_1465
BCH: Bcen2424_6363 Bcen2424_6378
BCM: Bcenmc03_7042
BCJ: BCAM2109
BAM: Bamb_5723
BAC: BamMC406_6475
BXE: Bxe_B1809 Bxe_B2381
AZO: azo0490
GUR: Gura_3450
MLO: mll2689 mlr0978
PLA: Plav_0704 Plav_1087 Plav_2363
SME: SM_b20054(cpo) SMa1809 SMc01944
SMD: Smed_3969 Smed_5825
ATU: Atu3463(cpoF) Atu3493 Atu4778(cpo) Atu5389
ATC: AGR_L_210 AGR_L_2670 AGR_L_2734 AGR_pAT_561
ARA: Arad_8698
AVI: Avi_5112
RET: RHE_CH01162(ypch00381) RHE_CH01902(ypch00622)
RHE_CH02571(ypch00867)
REC: RHECIAT_CH0002684 RHECIAT_PC0000075
RLE: RL2967(cpo) pRL110136(cpo) pRL120450(cpo)
RLT: Rleg2_1660 Rleg2_2211
RLG: Rleg_2506
RHI: NGR_b15830(cpo1) NGR_b15880(cpo2)
BME: BMEI0733
BJA: blr1251
BRA: BRADO1257 BRADO2692 BRADO4449(cpo) BRADO5130
BBT: BBta_1889(cpo) BBta_2279 BBta_4668(cpo)
RPA: RPA2105
RPB: RPB_0185 RPB_0194 RPB_3239 RPB_3504
RPC: RPC_4420
RPE: RPE_2277 RPE_4490
RPT: Rpal_2396
OCA: OCAR_6762
BTR: Btr_1151
XAU: Xaut_1276
AZC: AZC_1383 AZC_2704
MEX: Mext_3628
MEA: Mex_1p3884
MDI: METDI4449 METDI4619
MPO: Mpop_3910
MCH: Mchl_3920
HNE: HNE_3365
SAL: Sala_0477
GOX: GOX0738 GOX1766
GDI: GDI_0081(cpo)
BAN: BA5030
BAR: GBAA5030
BAA: BA_5447
BAT: BAS4670
BCE: BC4774
BCA: BCE_3158 BCE_4929
BCZ: BCZK4530
BTK: BT9727_4511
BTL: BALH_4349
BLD: BLi02236(yisY)
LLM: llmg_1737(cpo)
SAG: SAG2132
SAN: gbs2091
SAK: SAK_2071
STC: str1257
STL: stu1257
STE: STER_1236
EFA: EF1028
CTC: CTC01150
CKL: CKL_0764
MVA: Mvan_1567
MGI: Mflv_3146
MMC: Mmcs_1286
MKM: Mkms_1303
MJL: Mjls_1315
RHA: RHA1_ro01401 RHA1_ro02074 RHA1_ro02101
SCO: SCO0465(SCF76.05c)
SMA: SAV_974
TFU: Tfu_1653
FAL: FRAAL2804(cpo)
SEN: SACE_3365(cpo)
STP: Strop_3997 Strop_4189
ABA: Acid345_3102 Acid345_3745
RBA: RB2401(cpo) RB3694
SYN: slr0314
AVA: Ava_0013 Ava_3458 Ava_5030 Ava_C0107
CCH: Cag_1627
MAC: MA0993
 |
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| Structures |
PDB: 1A7U 1A88 1A8Q 1A8S 1A8U 1BRT 1CPO 1IDQ 1IDU 1QHB
1QI9 1VNC 1VNE 1VNF 1VNG 1VNH 1VNI 1VNS 2CIV 2CIW
2CIX 2CIY 2CIZ 2CJ0 2CJ1 2CJ2 2CPO 2J18 2J19 2J5M
3BB0 |
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Reference
Authors
Title
Journal
|
1 [PMID:1056179]
Hager LP, Hollenberg PF, Rand-Meir T, Chiang R, Doubek D.
Chemistry of peroxidase intermediates.
Ann. N. Y. Acad. Sci. 244 (1975) 80-93. |
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Reference
Authors
Title
Journal
Organism
|
2 [PMID:5949836]
Morris DR, Hager LP.
Chloroperoxidase. I. Isolation and properties of the crystalline
glycoprotein.
J. Biol. Chem. 241 (1966) 1763-8.
Caldariomyces fumago |
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Reference
Authors
Title
Journal
|
3
Theiler, R., Cook, J.C., Hager, L.P. and Siuda, J.F.
Halohydrocarbon synthesis by homoperoxidase.
Science 202 (1978) 1094-1096. |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.11.1.10
IUBMB Enzyme Nomenclature: 1.11.1.10
ExPASy - ENZYME nomenclature database: 1.11.1.10
BRENDA, the Enzyme Database: 1.11.1.10
CAS: 9055-20-3 |
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