| Entry |
|
|---|
| Name |
peroxidase;
myeloperoxidase;
lactoperoxidase;
verdoperoxidase;
guaiacol peroxidase;
thiocyanate peroxidase;
eosinophil peroxidase;
Japanese radish peroxidase;
horseradish peroxidase (HRP);
extensin peroxidase;
heme peroxidase;
MPO;
oxyperoxidase;
protoheme peroxidase;
pyrocatechol peroxidase;
scopoletin peroxidase |
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| Class |
Oxidoreductases;
Acting on a peroxide as acceptor;
Peroxidases
 |
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| Sysname |
donor:hydrogen-peroxide oxidoreductase |
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| Reaction(IUBMB) |
donor + H2O2 = oxidized donor + 2 H2O [RN:R03532] |
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| Reaction(KEGG) |
R03532 > R00602;
(other) R00698 R02596 R03919 R04007 R07443
 |
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| Substrate |
donor [CPD:C00030];
H2O2 [CPD:C00027] |
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| Product |
oxidized donor [CPD:C00028];
H2O [CPD:C00001] |
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| Cofactor |
Heme [CPD:C00032] |
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| Comment |
A hemoprotein. |
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| Pathway |
PATH: ec00360 Phenylalanine metabolism
PATH: ec00680 Methane metabolism
PATH: ec00940 Phenylpropanoid biosynthesis
PATH: ec01061 Biosynthesis of phenylpropanoids
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K00430 peroxidase
KO: K10788 eosinophil peroxidase
KO: K10789 myeloperoxidase
KO: K12550 lactoperoxidase |
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| Genes |
HSA: 4025(LPO) 4353(MPO) 8288(EPX) 9588(PRDX6)
PTR: 468420(EPX) 469589(PRDX6) 738041(PRDX6) 748680(MPO)
MCC: 706486(PRDX6) 707299 709655(EPX) 709848(LPO) 714246(MPO)
MMU: 11758(Prdx6) 13861(Epx) 17523(Mpo) 320769(Prdx6-rs1) 76113(Lpo)
RNO: 287610(Lpo) 303413(Mpo) 303414(Epx) 94167(Prdx6)
CFA: 480069(PRDX6) 491109(EPX) 491111(LPO) 609986(MPO)
BTA: 280844(LPO) 282438(PRDX6) 511206(MPO) 786533
SSC: 399538(PRDX6)
ECB: 100052382 100056877 100070907 100070920(MPO)
MDO: 100012462 100015705
OAA: 100074596 100081676
GGA: 417467(MPO) 429062(PRDX6)
TGU: 100228147 100230495
XLA: 394386(mpo-A) 398641 399434(prdx6)
XTR: 394706 496787(prdx6)
DRE: 100148035 393778(prdx6)
BFO: BRAFLDRAFT_57198
SPU: 579284
DME: Dmel_CG10211 Dmel_CG11765(Prx2540-2) Dmel_CG8913(Irc)
DPO: Dpse_GA10160 Dpse_GA21405
CEL: F09F3.5 T06D8.10(peroxidase)
NVE: NEMVE_v1g234225
ATH: AT1G05260(RCI3) AT1G14540 AT1G14550 AT1G24110 AT1G30870
AT1G34510 AT1G44970 AT1G49570 AT1G68850 AT1G71695 AT2G18140
AT2G18150 AT2G18980 AT2G22420 AT2G24800 AT2G34060 AT2G37130
AT2G38380 AT2G38390 AT2G39040 AT2G41480 AT2G43480 AT3G01190
AT3G03670 AT3G17070 AT3G21770 AT3G28200 AT3G49110(PRXCA)
AT3G49120(PRXCB) AT3G49960 AT4G08770 AT4G08780 AT4G11290
AT4G16270 AT4G17690 AT4G21960(PRXR1) AT4G26010 AT4G30170
AT4G31760 AT4G33420 AT4G36430 AT4G37520 AT4G37530 AT5G05340
AT5G06720 AT5G06730 AT5G14130 AT5G15180 AT5G17820 AT5G19880
AT5G19890 AT5G22410 AT5G24070 AT5G40150 AT5G42180 AT5G47000
AT5G51890 AT5G58390 AT5G58400 AT5G64100 AT5G64110 AT5G64120
AT5G66390 AT5G67400
OSA: 4324557(Os01g0963200) 4325127(Os01g0263000)
4326874(Os01g0543100) 4330684(Os02g0741200)
4332174(Os03g0234900) 4332175(Os03g0235000)
4335846(Os04g0423800) 4338164(Os05g0231900)
4340745(Os06g0274800) 4341861(Os06g0681600)
4342251(Os07g0115300) 4343309(Os07g0499500)
4344496(Os08g0113000) 4345222(Os08g0302000)
4347336(Os09g0471100) 4349587(Os11g0112400)
DHA: DEHA0F10593g
NCR: NCU06031
AFM: AFUA_4G08580
MBR: MONBRDRAFT_17605
DDI: DDB_0238006
PFA: PFL0595c
PPU: PP_0235(lsfA)
PSB: Psyr_4877
PFL: PFL_5939
PEN: PSEEN0215(lsfA)
PSA: PST_0214(lsfA)
PRW: PsycPRwf_1436
ACB: A1S_2863
ABY: ABAYE0619
MAQ: Maqu_0254
NOC: Noc_0878 Noc_1307
CSA: Csal_0179
CVI: CV_1938 CV_3739
RSO: RSc0754
RPI: Rpic_0704
RPF: Rpic12D_0770
REU: Reut_B4984
REH: H16_A2819
RME: Rmet_2654 Rmet_4131
BMA: BMA2066
BMV: BMASAVP1_A0844
BML: BMA10229_A2677
BMN: BMA10247_1932
BPS: BPSL2748
BPM: BURPS1710b_3239(lsfA)
BPL: BURPS1106A_3223(lsfA)
BPD: BURPS668_3186(lsfA)
BTE: BTH_I1388
BVI: Bcep1808_0748
BUR: Bcep18194_A3905 Bcep18194_B0181 Bcep18194_B1953
BCN: Bcen_0329
BCH: Bcen2424_0812
BCM: Bcenmc03_0781
BAM: Bamb_0693
BXE: Bxe_B2802
BPY: Bphyt_0775
POL: Bpro_2374 Bpro_4841
VEI: Veis_0864
HAR: HEAR3137
AZO: azo2663
DVU: DVU2247
RET: RHE_CH01791(ypch00605)
RLE: RL2003
RPA: RPA2443
RPB: RPB_3015
NWI: Nwi_1738
NHA: Nham_2167
JAN: Jann_4026
RDE: RD1_0634
PDE: Pden_2756
MMR: Mmar10_0498
GBE: GbCGDNIH1_0908
ACR: Acry_2948
GDI: GDI_2651
GDJ: Gdia_0864
FAL: FRAAL0302 FRAAL4492(ahpC)
SUS: Acid_5901
FJO: Fjoh_5017
RBA: RB11131 RB4293 RB633
TER: Tery_5038
NPH: NP2708A(perA)
 |
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| Structures |
PDB: 1ARP 1ARU 1ARV 1ARW 1ARX 1ARY 1ATJ 1BGP 1C8I 1CK6
1CXP 1D2V 1D5L 1D7W 1DNU 1DNW 1FHF 1GW2 1GWO 1GWT
1GWU 1GX2 1GZA 1GZB 1H3J 1H55 1H57 1H58 1H5A 1H5C
1H5D 1H5E 1H5F 1H5G 1H5H 1H5I 1H5J 1H5K 1H5L 1H5M
1HCH 1HSR 1KZM 1LY8 1LY9 1LYC 1LYK 1MHL 1MNP 1MYP
1PA2 1QO4 1SCH 1W4W 1W4Y 1XXU 2ATJ 2C0D 2E39 2E3A
2E3B 2E9E 2EFB 2EHA 2GJ1 2GJM 2IKC 2IPS 2NQX 2O86
2OJV 2PT3 2PUM 2QPK 2QQT 2QRB 2R5L 2Z5Z 3ATJ 3BXI
3ERH 3ERI 3F9P 3FNL 3GC1 3GCJ 3GCK 3GCL 3I6N 4ATJ
6ATJ 7ATJ |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:13172193]
KENTEN RH, MANN PJ.
A simple method for the preparation of horseradish peroxidase.
Biochem. J. 57 (1954) 347-8.
Armoracia rusticana |
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Reference
Authors
Title
Journal
Organism
|
2 [PMID:13475358]
MORRISON M, HAMILTON HB, STOTZ E.
The isolation and purification of lactoperoxidase by ion exchange
chromatography.
J. Biol. Chem. 228 (1957) 767-76.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
|
3
Paul, K.G.
Peroxidases.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 8, Academic Press, New York, 1963, p. 227-274. |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:13622706]
TAGAWA K, SHIN M, OKUNUKI K.
Peroxidases from wheat germ.
Nature. 183 (1959) 111.
Triticum aestivum |
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Reference
Authors
Title
Journal
|
5
Theorell, H.
Preparation and properties of crystalline horseradish peroxidase.
Ark. Kemi Mineral. Geol. 16A (1943) 11pp. |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.11.1.7
IUBMB Enzyme Nomenclature: 1.11.1.7
ExPASy - ENZYME nomenclature database: 1.11.1.7
BRENDA, the Enzyme Database: 1.11.1.7
CAS: 9003-99-0 |
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