| Entry |
|
|---|
| Name |
4-chlorophenylacetate 3,4-dioxygenase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of two atoms of
oxygen into the other donor
 |
|---|
| Sysname |
4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating,
dechlorinating) |
|---|
| Reaction(IUBMB) |
4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate
+ chloride + NAD+ [RN:R03306] |
|---|
| Reaction(KEGG) |
R03306
 |
|---|
| Substrate |
4-chlorophenylacetate [CPD:C03077];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
3,4-dihydroxyphenylacetate [CPD:C01161];
chloride [CPD:C00698];
NAD+ [CPD:C00003] |
|---|
| Cofactor |
Iron [CPD:C00023] |
|---|
| Comment |
A system, containing a reductase and an iron-sulfur oxygenase, and
no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl
acetate. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3745216]
Markus A, Krekel D, Lingens F.
Purification and some properties of component A of the
4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species
strain CBS.
J. Biol. Chem. 261 (1986) 12883-8.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.12.9
IUBMB Enzyme Nomenclature: 1.14.12.9
ExPASy - ENZYME nomenclature database: 1.14.12.9
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.12.9
BRENDA, the Enzyme Database: 1.14.12.9
CAS: 105006-00-6 |
|---|
