| Entry |
|
|---|
| Name |
flavonoid 3'-monooxygenase;
flavonoid 3'-hydroxylase;
flavonoid 3-hydroxylase (erroneous);
NADPH:flavonoid-3'-hydroxylase;
flavonoid 3-monooxygenase (erroneous) |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
 |
|---|
| Sysname |
flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating) |
|---|
| Reaction(IUBMB) |
a flavonoid + NADPH + H+ + O2 = a 3'-hydroxyflavonoid + NADP+ + H2O
[RN:R03615] |
|---|
| Reaction(KEGG) |
R03615 > R02442 R03124 R06537 R06538 R08002 R08032
 |
|---|
| Substrate |
flavonoid [CPD:C01579];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
3'-hydroxyflavonoid [CPD:C02790];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Comment |
Acts on a number of flavonoids, including naringenin and
dihydrokaempferol. Does not act on 4-coumarate or 4-coumaroyl-CoA. |
|---|
| Pathway |
PATH: ec00941 Flavonoid biosynthesis
PATH: ec00944 Flavone and flavonol biosynthesis
PATH: ec01061 Biosynthesis of phenylpropanoids
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K05280 flavonoid 3'-monooxygenase |
|---|
| Genes |
ATH: AT5G07990(TT7)
POP: POPTR_823742(F3H1)
VVI: 100232999(GSVIVT00016217001)
OSA: 4348304(Os10g0320100)
 |
|---|
Reference
Authors
Title
Journal
|
1
Forkmann, G., Heller, W. and Grisebach, H.
Anthocyanin biosynthesis in flowers of Matthiola incana flavanone 3-
and flavonoid 3'-hydroxylases.
Z. Naturforsch. C: Biosci. 35 (1980) 691-695. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.13.21
IUBMB Enzyme Nomenclature: 1.14.13.21
ExPASy - ENZYME nomenclature database: 1.14.13.21
BRENDA, the Enzyme Database: 1.14.13.21
CAS: 75991-44-5 |
|---|
