| Entry |
|
|---|
| Name |
formate dehydrogenase (NADP+);
NADP+-dependent formate dehydrogenase;
formate dehydrogenase (NADP+) |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
formate:NADP+ oxidoreductase |
|---|
| Reaction(IUBMB) |
formate + NADP+ = CO2 + NADPH [RN:R00134] |
|---|
| Reaction(KEGG) |
R00134
 |
|---|
| Substrate |
formate [CPD:C00058];
NADP+ [CPD:C00006] |
|---|
| Product |
CO2 [CPD:C00011];
NADPH [CPD:C00005] |
|---|
| Cofactor |
Iron [CPD:C00023];
Tungsten [CPD:C00753];
Selenium [CPD:C01529] |
|---|
| Comment |
A tungsten-selenium-iron protein. |
|---|
| Pathway |
PATH: ec00680 Methane metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K05299 formate dehydrogenase (NADP+) |
|---|
| Genes |
WSU: WS0477(fdhB)
 |
|---|
| Structures |
PDB: 2GSD |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4154039]
Andreesen JR, Ljungdahl LG.
Nicotinamide adenine dinucleotide phosphate-dependent formate
dehydrogenase from Clostridium thermoaceticum: purification and
properties.
J. Bacteriol. 120 (1974) 6-14.
Clostridium thermoaceticum |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6822536]
Yamamoto I, Saiki T, Liu SM, Ljungdahl LG.
Purification and properties of NADP-dependent formate dehydrogenase
from Clostridium thermoaceticum, a tungsten-selenium-iron protein.
J. Biol. Chem. 258 (1983) 1826-32.
Clostridium thermoaceticum |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.43
IUBMB Enzyme Nomenclature: 1.2.1.43
ExPASy - ENZYME nomenclature database: 1.2.1.43
BRENDA, the Enzyme Database: 1.2.1.43
CAS: 51377-43-6 |
|---|
