| Entry |
|
|---|
| Name |
carboxylate reductase;
aldehyde:(acceptor) oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With other acceptors
 |
|---|
| Sysname |
aldehyde:acceptor oxidoreductase |
|---|
| Reaction(IUBMB) |
an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor
[RN:R00544] |
|---|
| Reaction(KEGG) |
R00544 > R00326 R00638
 |
|---|
| Substrate |
aldehyde [CPD:C00071];
acceptor [CPD:C00028];
H2O [CPD:C00001] |
|---|
| Product |
carboxylate [CPD:C00060];
reduced acceptor [CPD:C00030] |
|---|
| Cofactor |
Tungsten [CPD:C00753] |
|---|
| Comment |
A tungsten protein. Methyl viologen can act as acceptor. In the
reverse direction, non-activated acids are reduced by reduced
viologens to aldehydes, but not to the corresponding alcohols. |
|---|
| Pathway |
PATH: ec00620 Pyruvate metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:2550230]
White H, Strobl G, Feicht R, Simon H.
Carboxylic acid reductase: a new tungsten enzyme catalyses the
reduction of non-activated carboxylic acids to aldehydes.
Eur. J. Biochem. 184 (1989) 89-96.
Clostridium thermoaceticum |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.99.6
IUBMB Enzyme Nomenclature: 1.2.99.6
ExPASy - ENZYME nomenclature database: 1.2.99.6
BRENDA, the Enzyme Database: 1.2.99.6
CAS: 125008-36-8 |
|---|
