| Entry |
|
|---|
| Name |
quinoline-4-carboxylate 2-oxidoreductase;
quinaldic acid 4-oxidoreductase;
quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors
 |
|---|
| Sysname |
quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating) |
|---|
| Reaction(IUBMB) |
quinoline-4-carboxylate + acceptor + H2O =
2-oxo-1,2-dihydroquinoline-4-carboxylate + reduced acceptor
[RN:R05183] |
|---|
| Reaction(KEGG) |
R05183
 |
|---|
| Substrate |
quinoline-4-carboxylate [CPD:C06414];
acceptor [CPD:C00028];
H2O [CPD:C00001] |
|---|
| Product |
2-oxo-1,2-dihydroquinoline-4-carboxylate [CPD:C16715];
reduced acceptor [CPD:C00030] |
|---|
| Comment |
A molybdenum---iron---sulfur flavoprotein with molybdopterin
cytosine dinucleotide as the molybdenum cofactor. Quinoline,
4-methylquinoline and 4-chloroquinoline can also serve as substrates
for the enzyme from Agrobacterium sp. 1B. Iodonitrotetrazolium
chloride, thionine, menadione and 2,6-dichlorophenolindophenol can
act as electron acceptors. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:1418685]
Bauer G, Lingens F.
Microbial metabolism of quinoline and related compounds. XV.
Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium
spec.1B: a molybdenum-containing enzyme.
Biol. Chem. Hoppe. Seyler. 373 (1992) 699-705.
Agrobacterium sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.99.19
IUBMB Enzyme Nomenclature: 1.3.99.19
ExPASy - ENZYME nomenclature database: 1.3.99.19
BRENDA, the Enzyme Database: 1.3.99.19
CAS: 175780-18-4 |
|---|
