KEGG   ENZYME: 1.7.3.4Help
Entry
EC 1.7.3.4                  Enzyme                                 

Name hydroxylamine oxidase;
HAO (ambiguous;
cf. EC 1.7.99.8, hydroxylamine oxidoreductase);
hydroxylamine oxidoreductase (ambiguous;
cf. EC 1.7.99.8, hydroxylamine oxidoreductase)
Class Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With oxygen as acceptor
BRITE hierarchy
Sysname hydroxylamine:oxygen oxidoreductase
Reaction(IUBMB) hydroxylamine + O2 = nitrite + H2O [RN:R00793]
Reaction(KEGG) R00793
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Substrate hydroxylamine [CPD:C00192];
O2 [CPD:C00007]
Product nitrite [CPD:C00088];
H2O [CPD:C00001]
Cofactor Heme [CPD:C00032]
Comment A hemoprotein with seven c-type hemes and one P-460-type heme per
subunit.
Pathway PATH: ec00910  Nitrogen metabolism
Orthology KO: K10535  hydroxylamine oxidase
Genes MCA: MCA0956
NOC: Noc_0892
NEU: NE0962(hao2)
NET: Neut_1672 Neut_1793
NMU: Nmul_A0805 Nmul_A1082 Nmul_A2662
CFF: CFF8240_0800
CCV: CCV52592_0434
GUR: Gura_1628
DDE: Dde_0300
DOL: Dole_1634
SFU: Sfum_2550
SIL: SPOA0201
MBU: Mbur_0467
Taxonomy
Structures PDB: 1FGJ  
Reference
  Authors
  Title

  Journal
  Organism
1  [PMID:7117545]
Hooper AB, Balny C.
Reaction of oxygen with hydroxylamine oxidoreductase of
Nitrosomonas: fast kinetics.
FEBS. Lett. 144 (1982) 299-303.
Nitrosomonas sp.
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:6289867]
Lipscomb JD, Hooper AB.
Resolution of multiple heme centers of hydroxylamine oxidoreductase
from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy.
Biochemistry. 21 (1982) 3965-72.
Nitrosomonas europeae [GN:neu]
Reference
  Authors
  Title

  Journal
  Organism
3  [PMID:5758552]
Rees MK.
Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I.
Purification of hydroxylamine oxidase.
Biochemistry. 7 (1968) 353-66.
Nitrosomonas europeae [GN:neu]
Other DBs ExplorEnz - The Enzyme Database: 1.7.3.4
IUBMB Enzyme Nomenclature: 1.7.3.4
ExPASy - ENZYME nomenclature database: 1.7.3.4
BRENDA, the Enzyme Database: 1.7.3.4
CAS: 9075-43-8

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