| Entry |
|
|---|
| Definition |
dihydrofolate reductase-thymidylate synthase
|
|---|
| Orthology |
|
|---|
| Organism |
|
|---|
| Pathway |
| Pyrimidine metabolism | | One carbon pool by folate | | Folate biosynthesis | | Metabolic pathways |
|
|---|
| Class |
Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH: lmi00240]
Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH: lmi00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH: lmi00670]
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GI: NCBI-GeneID: UniProt: |
|---|
| Position |
6
|
|---|
| AA seq |
520 aa  
MSRAAAKFKIPMPVTKADFAFPSLRAFSIVVALDKQHGIGDGESIPWRVPEDMAFFKDQT
TLLRNKKPPTDKKRNAVVMGRKTWESVPVKFRPLKGRLNVVLSSKATVEELLAPLPEEKR
AAAAQDIVVVNGGLAAALRLLARPPYCSSIETAYCVGGAQVYADAMLSPCVEKLQEVYLT
RIHTTAPACTRFFPFPPENAATAWDLASSQGRRKSAVDGLEFEICKYVPRNHEERQYLEL
IDRIMKTGIAKEDRTGVGTLSLFGAQMRFSLRDNRLPLLTTKRVFWRGVCEELLWFLRGE
TNAQLLADKDIHIWDGNGSREFLDSRGLTENTEMDLGPVYGFQWRHFGAEYRGLEANYDG
EGVDQIKFIVETIKANPNDRRLLFTAWNPCALHKMALPPCHLLAQFYVNTEKSELSCMLY
QRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYRSHIGALKAQLERVP
HAFPTLVFKEERQFLEDYELMDMEVIDYVPHPAIKMDMAV |
|---|
| NT seq |
1563 nt  +upstreamnt +downstreamnt
atgtccagggcggctgcgaagttcaagattccgatgccggtgacgaaggcggacttcgcc
ttcccctccctgcgcgccttctccatcgtcgtggccctcgataagcagcacggcatcggc
gacggcgagtcgatcccgtggcgggtgccggaggacatggcgttcttcaaggaccagacg
acgctgctgcgcaacaagaagccgccgacggacaagaagcgcaacgccgtcgtgatgggg
cgcaagacgtgggagagcgttccggtaaagttccggccactcaagggccggctgaacgtt
gtgttgtcctcgaaggccaccgtcgaggagcttctggcgccactgccggaggaaaagcgc
gcggcggcggcgcaggacattgtggtggtgaacggcggtctggccgcggcgctccgcctc
ctcgcacgtccgccgtactgcagctccatcgagacggcgtactgcgtcggcggtgcgcag
gtgtatgcggacgccatgctgtcgccatgcgtcgagaagctgcaggaggtgtacctgacc
cgcatccacacgacggcgcctgcgtgcacgcgcttcttcccgtttcctcccgagaacgcc
gccacggcgtgggacctggcgtcgtctcagggacgccgcaagagcgcggtggacggcctc
gagttcgagatttgcaagtacgtgccgcgcaaccacgaggagcggcagtaccttgagctg
attgaccgcatcatgaagacggggatcgcgaaggaggaccgcaccggggtgggcaccttg
agcctcttcggcgcacagatgcggttctccctacgcgacaaccgcctgccactgctgacg
acgaagcgcgtcttctggcgaggcgtgtgcgaggagttgctgtggttcctgcgcggggag
acaaacgcgcagctgctcgcggacaaggacatacacatctgggacggcaacggctcgcgc
gagtttctcgacagccgcggcttgacagagaatacggagatggacctcggccctgtctac
ggcttccagtggcgccacttcggggcagaataccgggggctcgaagcgaactacgacggc
gagggggtggaccagatcaagttcatcgtggagacgatcaaggcgaacccgaacgaccgc
cgtcttctgttcactgcgtggaacccgtgcgcgctgcacaagatggcactgccgccgtgc
cacttgctcgctcaattctacgtgaacacggagaagagcgagctatcctgcatgctgtac
caacgttcgtgcgacatgggcctcggcgtccccttcaacatcgcctcctacgcgctgctc
accatcctcattgccaaggcgacgggtctgcggcctggtgagcttgtgcacaccctcggc
gacgcccacgtctaccgcagtcacatcggtgccctcaaggcgcagctcgagcgagtcccg
cacgcgttcccgaccctcgtgttcaaggaggagcggcagttcctcgaggactacgagttg
atggacatggaggtgatcgactacgtgccgcacccggcgatcaagatggatatggccgta
tag |
|---|
