KEGG   Loa loa (eye worm): LOAG_00547Help
Entry
LOAG_00547        CDS       T02664                                 

Definition
variant SH3 domain-containing protein
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
loa  Loa loa (eye worm)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Calcium signaling pathway
Phosphatidylinositol signaling system
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:loa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    LOAG_00547
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    LOAG_00547
   04020 Calcium signaling pathway
    LOAG_00547
   04070 Phosphatidylinositol signaling system
    LOAG_00547
Enzymes [BR:loa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     LOAG_00547
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
AA seq 1334 aa AA seqDB search
MHPQSSTDSVLLSQRSVLFSPLSTTSSLITSRSVEFAMEKVFHAMEMGHNVYKLLLMKRR
DPAQKRLTYNRETRQLFLSKLDNSDKVKIHAKDFLCASWSSSKTLRLDLRVVKEVHTLDY
KLRKIKIGDKWEKDKEFKQFDAARILVLSYATSFNLRYWILLFDTEELCRMWCQGVHHLM
LDTISACHALLVERWLRKEFYNIAGYGLENPWLFPRLWGQKKLAGGPRPARDAQISVAMK
HMKPFVHTSLQYKVQSKQLQEDIMYYDTFAIAYRKLLHSNSLFAEHFAAYSDDAAVVSFN
NFLRFHKDKQNDEIGMMRERASDFLRHFLREWDPYRDVPEPTLSVTEFCDFLFSRENSLW
DSVNENVIHDMNRPLSHYWIASSHNTYLTGDQLKSESSLDTYARALLMGCRCVELDCWDG
QKRSSGEIQDIVIYHGYTMTSKINLRDVLYTIRHYAFINSEFPVILSIEDNCSVPVQRLL
AREIREILGNYLLTAPVSREETCLPSPAALKRKIILKHKKLPTESENIASQQTDEDQEQD
LLSLNFTRQGILSLKSGVNDEWTTHLFVLFPDRLCYMLEQCESNFNNQGILRRQDSLGNA
QDDENQDGLTNLTGFVVPQEEMHVTEEWFHGKTDRDTARMRLLEHKDKGNGLFLVRDSTI
FIGDYSLSFLHNEKVHHCRIRTRMVNGERKYYFLENKQMDTLYELISHYTKERLRTPNFS
TTLVTPCPQPCPHLGMIWFCEKTDRNRAEELLNTVQQDGAFLLRFSSTDKNVFVLSLRVD
GEIWHYHLKRDGRIFVVNQTLFENLNQIVEFYSTREFVHGICLKYPVGENTITDSTGAWF
SADRAPGCYMELKDIDKEILVRAIEPYNGSLPSELSFPINAVIRVFRKDGDRWRGKYGIH
SGFFPSRCVIELENSDNMSNELSVYAAIDLADSLIEEVPFEVAGRPFAFKIRRVSAHWNP
SEYVLAANSNEDREDWLNILHELTRTATDRNTLIRTREKNLRIASELSDLVVYCQAVPFN
SQFATQGNFYEMCSFSETKFEKLMERGLVQFNSRQLSRVYPQGSRVTSANYDPVPMWNAA
CHMVALNYQTGDRSMQLNQGKFMANGQCGYVLKPSYMIDEMFSPDAAEVVSTSCPIILTV
HVIAGQHLSRKDRNRGICSPVVTVEIVGLPADSSTIRTRAIASNGLNPVWNEKFSFKVYC
PEIALLRLYVEDGDFMGPKMDPFIGQAVYPLDCIRTGFRSVPLRNQYGEELELSSLLVYL
DMRDQSNEAEVLNPHVALQAGRCFAGGLHKTLSSSGIFWARLNSADQSDFKPPLSPNISA
AKHIPVPMDLTSLE
NT seq 4005 nt NT seq  +upstreamnt  +downstreamnt
atgcaccctcaaagctcaacagattcggtattattatctcagcgttcagtattattctct
cccctatctacaactagttcgcttataacatcacgctcagtggaatttgcaatggaaaaa
gtgtttcatgcaatggaaatgggtcataacgtttacaaacttctgttgatgaaacgacgg
gatccagcacaaaaaaggttgacttataaccgtgagacaaggcagctgtttttgtcaaag
ctagataattctgacaaggttaaaattcatgctaaagattttttgtgtgcttcatggagt
agcagtaaaactctgcgattagatttacgagtagtgaaggaagtgcatacacttgattat
aaactaagaaagatcaaaatcggcgacaagtgggaaaaggacaaagaattcaaacagttt
gatgcagctagaatattagttctaagttatgcgacgagtttcaatttgcggtattggatt
ttgttattcgatacggaagagttatgtcgaatgtggtgtcagggtgttcaccacttgatg
ctggatacaatttctgcttgtcatgcacttctcgtggaacgatggctcaggaaagagttc
tataatattgctggttatggtctcgaaaacccttggcttttcccgcggctctgggggcag
aaaaagcttgctggaggaccgcgtccggcccgcgatgctcagatcagcgtagcgatgaaa
cacatgaagcctttcgtgcatactagtttgcagtataaggtacaatcaaaacaattgcaa
gaagacataatgtattatgatactttcgcaattgcttatcgcaaacttttgcattctaat
tctcttttcgcagaacattttgcagcttactcggatgatgcggctgttgtcagcttcaac
aatttcctgcggtttcacaaggataaacaaaatgatgaaatagggatgatgcgcgaaaga
gccagtgattttcttaggcatttcttaagggaatgggatccatatagagatgttcctgaa
ccaacccttagcgtgactgaattttgcgacttcctcttctctcgcgaaaattcactatgg
gattctgttaacgagaatgttatacatgacatgaatcgaccactaagtcactactggatt
gcttcatcacacaacacatatcttaccggtgatcaactcaagagtgaatcctcgttggat
acgtatgctcgagctttgcttatgggctgtagatgtgttgaactcgactgctgggatgga
caaaagagaagttcaggtgaaatacaagatattgttatttaccatggttacacaatgact
agtaaaatcaatttgcgcgatgtgctttacaccattcgtcattacgcttttattaacagc
gagtttccagtgattctctcgattgaagacaattgttcagtaccggtacaacggttgctt
gctcgtgaaattagagaaattcttggtaattatttactcacagctccagttagtcgtgaa
gaaacttgtttaccatctccggcagctctgaagcgaaaaattatcttgaagcataagaaa
ctgccgacggaaagtgaaaatattgcttcacagcaaactgatgaggatcaagaacaggat
ttactttcactgaattttactcggcaaggaattctgtcattgaaaagtggtgtaaacgat
gaatggacaactcacttatttgtattgtttccggatcgtttgtgttatatgctggaacag
tgcgaaagtaatttcaataatcaggggattctgagacgtcaagattcactggggaacgca
caggatgatgaaaatcaggatggtttgacaaacttgacaggtttcgttgtacctcaagaa
gaaatgcatgttacagaagaatggtttcatggcaaaacagatcgagatacagcaagaatg
cgtcttttggaacacaaagataaaggcaatggtctttttttggttcgcgattcaactatt
ttcattggcgactactccttatcgtttctgcataatgagaaagtacatcactgtcgaata
cgcaccaggatggtgaatggtgaaagaaaatattattttttggaaaataagcaaatggat
acactttatgagcttatatcgcactatacgaaggaaagattgaggacaccgaattttagc
acaacactggtcactccatgtccgcagccttgtcctcatctcggaatgatatggttttgt
gagaaaacagatagaaatcgtgccgaagaacttctgaacacggttcaacaagatggggct
ttcttgctgcgcttcagttctactgataaaaatgttttcgtgctttctctaagagttgac
ggcgaaatatggcattaccatttgaaacgtgatggtcgaatttttgttgtcaaccagaca
cttttcgagaatttgaatcaaatagttgaattttattcaacaagagaattcgttcatgga
atatgtctgaaatatcccgtgggtgagaatactattactgattctacaggtgcatggttt
agtgcagatcgagcacctggttgttatatggaactcaaggacattgataaagagatattg
gttcgggctattgagccgtacaatggatctcttcccagcgagctttcattccctataaat
gcagtgataagagtattcagaaaagacggtgatcgctggcgtggcaaatatggcattcat
tcaggtttctttccttctcgatgcgttattgaactggaaaattctgataatatgtcgaat
gaattgagcgtttatgcagcaatcgatttggctgattctttgattgaagaagtaccgttt
gaagttgctggtcgaccgtttgcatttaaaattagacgtgtttcagcgcactggaatcca
agcgaatatgttttggcagctaattcaaatgaagatcgtgaagactggttaaatattctg
cacgagctgactagaacagctacggatcgcaataccttgatacgtacacgagaaaagaat
ttgcgaatagcttctgaattgtctgatttggtggtttactgccaggctgtccctttcaat
tcacaattcgcaacacaaggcaatttctatgagatgtgctcgttcagtgaaacaaaattc
gagaaactgatggaacgaggtttagttcagtttaattctcgtcagttgtcacgtgtttat
ccgcaaggttcacgtgttacttctgcaaattatgatccggtaccgatgtggaatgccgca
tgccatatggttgcactgaattaccaaactggcgataggtcgatgcagctaaatcagggt
aaatttatggcaaatggtcagtgtggatatgtgctgaaaccatcttatatgatcgatgaa
atgttttctccagatgctgccgaagtagtgtctacctcttgtccaatcattcttactgtt
catgtaatagcaggacagcatttgtcaaggaaagatagaaatcgaggtatctgttctcca
gttgttactgtagaaattgtcggtttgccggctgattcatccactattcgaacacgagct
attgcttccaatggcctgaatcctgtttggaatgagaaattcagcttcaaagtttactgt
ccagaaatagctttacttcgcttatatgttgaagatggtgattttatgggacccaaaatg
gatccatttattggacaggctgtgtatccacttgactgcattcgcactggttttcgatct
gtgccacttcgtaatcagtatggcgaagaattggaattgtcatcgttactcgtttatctc
gatatgcgcgatcaaagtaatgaagcagaagttctaaatccacacgttgctttgcaggct
ggccgatgttttgccggtggattgcataaaacgttatcatcatctggtatattttgggca
cgattgaattcagccgatcagagtgatttcaaaccaccactgtcacccaatatatcagct
gcaaaacacattccagttccgatggatttaacatccttagagtaa

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