KEGG   Lacticaseibacillus rhamnosus GG: LGG_01323
Entry
LGG_01323         CDS       T00987                                 
Symbol
pdhD
Name
(GenBank) Pyruvate dehydrogenase complex, E3 component,dihydrolipoamide dehydrogenase
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
lrh  Lacticaseibacillus rhamnosus GG
Pathway
lrh00010  Glycolysis / Gluconeogenesis
lrh00020  Citrate cycle (TCA cycle)
lrh00260  Glycine, serine and threonine metabolism
lrh00280  Valine, leucine and isoleucine degradation
lrh00310  Lysine degradation
lrh00380  Tryptophan metabolism
lrh00620  Pyruvate metabolism
lrh00630  Glyoxylate and dicarboxylate metabolism
lrh00640  Propanoate metabolism
lrh00785  Lipoic acid metabolism
lrh01100  Metabolic pathways
lrh01110  Biosynthesis of secondary metabolites
lrh01120  Microbial metabolism in diverse environments
lrh01200  Carbon metabolism
lrh01210  2-Oxocarboxylic acid metabolism
lrh01240  Biosynthesis of cofactors
Module
lrh_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:lrh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    LGG_01323 (pdhD)
   00020 Citrate cycle (TCA cycle)
    LGG_01323 (pdhD)
   00620 Pyruvate metabolism
    LGG_01323 (pdhD)
   00630 Glyoxylate and dicarboxylate metabolism
    LGG_01323 (pdhD)
   00640 Propanoate metabolism
    LGG_01323 (pdhD)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    LGG_01323 (pdhD)
   00280 Valine, leucine and isoleucine degradation
    LGG_01323 (pdhD)
   00310 Lysine degradation
    LGG_01323 (pdhD)
   00380 Tryptophan metabolism
    LGG_01323 (pdhD)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    LGG_01323 (pdhD)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lrh04147]
    LGG_01323 (pdhD)
Enzymes [BR:lrh01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     LGG_01323 (pdhD)
Exosome [BR:lrh04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   LGG_01323 (pdhD)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 FAD_oxidored GIDA FAD_binding_2 DAO HI0933_like AlaDh_PNT_C NAD_binding_7 NAD_binding_8 DFP 3HCDH_N FAD_binding_3 TrkA_N UDPG_MGDP_dh_N Thi4
Other DBs
NCBI-ProteinID: CAR87218
UniProt: A0A7S7FNU3
Position
1320182..1321585
AA seq 467 aa
MVVGDFAIDLDTVVIGSGSGGYVAAIRAAEMGQKVTVIENTFIGGVCLNVGCIPSKALIN
AGHRYQDALEASTFGINAKGADLDFKKTQDWKQNKVVHTLTSGVAMLLKKHKIETIMGTA
FLKDDHSLRVMQKDSAQTYTFKNLIIATGSRPIEIKGFKFGKRILDSTGGLNLPEVPKEF
VVIGGGYIGSELASAYANLGAHVTILEGTSSILPNFEKDMVQLVLNSFKKRGVTVITNAM
AKEAEDTGNGVKVTYTADGKEQTIAADYVMVTVGRRPNTDDLGLDIVGIETTDRGLIKVD
AQGRTNKPNIFAIGDIVPGAALAHKASYEGKIAAEAISGKASAVDYKAMPAVCFTDPELA
TTGMTLAEAKDKGIKAKASKFPFAANGRALSLAQTEGFVRLVTDENGTVIGGQVAGAGAS
DLISELTVAVEGGLNAEDLALTIHPHPTLSETIMDDAEVALGLPINI
NT seq 1404 nt   +upstreamnt  +downstreamnt
atggttgtaggcgattttgcaatcgatttggacaccgttgtgattggctctggctcaggt
ggttacgtagctgcgatccgagcagccgaaatgggtcagaaggtaactgttatcgagaat
accttcattggcggggtttgtttgaatgttggctgtatcccatcaaaagctttgatcaat
gccggtcaccgttatcaagatgccttggaagcaagcacgtttggtattaatgccaagggc
gcggatcttgatttcaaaaaaacccaggattggaagcaaaacaaggttgtgcacacgtta
accagcggtgttgcgatgcttttaaaaaagcacaaaatcgaaaccatcatggggacggct
ttcttgaaagatgatcatagtctgcgggttatgcaaaaagactcggctcagacatacacc
ttcaagaatttgatcattgcaaccggaagccggccaattgaaatcaaaggcttcaaattt
ggcaaacggattttggattcaaccggtggcctaaacttaccggaagtaccaaaagaattc
gtggtgattggcggtggctacatcggatccgaactggcgagcgcctatgccaacttaggc
gcacatgtcacaattcttgaaggcaccagctcaattttgccaaactttgaaaaggatatg
gttcaactcgtcttgaactcctttaaaaagcgcggcgttacagtgattaccaacgcgatg
gcgaaggaagccgaagataccggcaatggcgtcaaggtaacctatacagcggacggtaaa
gaacaaaccattgccgcagattatgtgatggtcacagtcgggcggcggccaaataccgat
gatttgggcttagacattgttggcattgaaacaacggatcgcggcttgatcaaagtcgat
gcgcaaggacgaaccaataagcctaatatttttgcaatcggtgacattgttcccggtgct
gcattagcgcataaagcaagttacgaaggtaagatagcggctgaggcgatcagtggcaag
gcaagcgcggttgactataaagcaatgccggctgtttgtttcacggatccagaactggct
acaactggcatgacgcttgctgaggccaaggataaaggcattaaagctaaagcaagcaag
tttccatttgcggcgaatggccgtgctttaagtttggcgcaaaccgagggcttcgttcgt
ctggttacggatgaaaacggaaccgtcatcggtggtcaagttgctggtgccggtgccagt
gatttgatctcagaattaacggtcgcggttgaaggtggacttaacgctgaagatttggct
ttgaccatccatccacatccgaccttaagtgaaaccattatggatgatgctgaagttgca
ttagggttgccaattaatatctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (23)   
   KEGG PATHWAY (16)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (18)   
   Pfam (18)   
All databases (87)   

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