KEGG   Lipotes vexillifer (Yangtze River dolphin): 103074544
Entry
103074544         CDS       T03090                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04020  Calcium signaling pathway
lve04022  cGMP-PKG signaling pathway
lve04024  cAMP signaling pathway
lve04218  Cellular senescence
lve04260  Cardiac muscle contraction
lve04261  Adrenergic signaling in cardiomyocytes
lve04270  Vascular smooth muscle contraction
lve04530  Tight junction
lve04713  Circadian entrainment
lve04723  Retrograde endocannabinoid signaling
lve04724  Glutamatergic synapse
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04727  GABAergic synapse
lve04728  Dopaminergic synapse
lve04911  Insulin secretion
lve04912  GnRH signaling pathway
lve04921  Oxytocin signaling pathway
lve04924  Renin secretion
lve04925  Aldosterone synthesis and secretion
lve04927  Cortisol synthesis and secretion
lve04929  GnRH secretion
lve04930  Type II diabetes mellitus
lve04934  Cushing syndrome
lve04935  Growth hormone synthesis, secretion and action
lve04973  Carbohydrate digestion and absorption
lve05010  Alzheimer disease
lve05020  Prion disease
lve05022  Pathways of neurodegeneration - multiple diseases
lve05031  Amphetamine addiction
lve05207  Chemical carcinogenesis - receptor activation
lve05410  Hypertrophic cardiomyopathy
lve05412  Arrhythmogenic right ventricular cardiomyopathy
lve05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103074544 (CACNA1D)
   04020 Calcium signaling pathway
    103074544 (CACNA1D)
   04024 cAMP signaling pathway
    103074544 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    103074544 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103074544 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    103074544 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    103074544 (CACNA1D)
   04929 GnRH secretion
    103074544 (CACNA1D)
   04912 GnRH signaling pathway
    103074544 (CACNA1D)
   04921 Oxytocin signaling pathway
    103074544 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    103074544 (CACNA1D)
   04924 Renin secretion
    103074544 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    103074544 (CACNA1D)
   04927 Cortisol synthesis and secretion
    103074544 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    103074544 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    103074544 (CACNA1D)
   04270 Vascular smooth muscle contraction
    103074544 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103074544 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    103074544 (CACNA1D)
   04727 GABAergic synapse
    103074544 (CACNA1D)
   04725 Cholinergic synapse
    103074544 (CACNA1D)
   04728 Dopaminergic synapse
    103074544 (CACNA1D)
   04726 Serotonergic synapse
    103074544 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    103074544 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103074544 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    103074544 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103074544 (CACNA1D)
   05020 Prion disease
    103074544 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    103074544 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    103074544 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103074544 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103074544 (CACNA1D)
   05414 Dilated cardiomyopathy
    103074544 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103074544 (CACNA1D)
   04934 Cushing syndrome
    103074544 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:lve04040]
    103074544 (CACNA1D)
Ion channels [BR:lve04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   103074544 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 103074544
NCBI-ProteinID: XP_007447289
UniProt: A0A340WJK8
Position
Unknown
AA seq 2182 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPAPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEGGGEESKRNTSMPASETESVNTENVSG
EGENQGCCGSLWCWCRRRGATKAGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAVK
SVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQA
YFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVA
SLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQI
LTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
NTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTVDDYREEDEDKDPYPPC
DVPVGEEEEEEEEDEPEVPAGPRPRRMSELNMKEKITPIPEGSAFFILSKTNPIRVGCHK
LINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTF
GAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFIL
YKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPI
YNYRVEISVFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILN
MVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIVDVALSEADPTESENVPVPT
ATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLF
FIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLC
DPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH
LDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSD
GTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEV
TVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKSSTIALQAGLRTLHDIGPEIRRAISCD
LQDDEPEESKGKEEGDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPA
SDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHVS
ENGHHSFHKHGREPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPEIHGYFRDPCCLG
EQENFSSEECYEDDSSPTGSRQSYSCGYYTRYPGSSLDFERPRGYHHPQSFSEDDDSPVC
YDSRRSPRRRLLPPTPTSPRRSSFNFECLRRHSSQEEVPPSPAFPHRTALPLHLMQQQIM
AVAGLDSSKAQKYSPSHSTRSWATPPATPSYRDWTPCYTPLIQVERSEATDQVNGSLPSL
HRSSWYTDEPSVSYRTFTPASLTVPRSFHNKNSDKQRSADSLVEAVLISEGLGRYARDPK
FVSATKHEIADACDLTIDEMESAASNLLNGNVHPRANGAVGPVSRRQDYELQDFGPGYSD
EEPDPGRDEEDLADEMICITTL
NT seq 6549 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagccgcgatcgacgctgct
agacaagccaaggctgcccaaactatgagcacctctgcacccgcacctgtaggatctctc
tcccaaagaaaacgtcagcaatatgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgaaacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttagaaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggcaaccactccagtggcaaatcgggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccatcataaaagccatggttcccctccttcacatagcccttttggtgttattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaggaggacccagcaccgtgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacagagtgcaggagtggctgggttggcccc
aatggcggcatcaccaactttgataactttgcctttgctatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagggaaaaggcgaaagcgcgggga
gacttccagaagctgcgggaaaagcagcagctggaagaggatctcaagggctacttggac
tggatcacccaagcggaagacatcgatcccgagaacgaaggaggaggagaggaaagcaag
cgaaataccagcatgcccgccagtgagacggagtctgtgaacacggagaacgtgagtggg
gaaggcgagaaccaaggctgctgtgggagcctctggtgctggtgcagaagaagaggcgcc
accaaggccgggccctctgggtgtcggcggtggggtcaagccatctcaaagtccaagctc
agccgacgctggcgccgctggaaccgcttcagtcgcagaaggtgtagggctgctgtgaag
tcggtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatttcc
tctgagcactacaaccagcctgactggttgacacagattcaagatatcgctaacaaagtc
ctcttggctctgttcacctgcgagatgcttgtaaagatgtacagcttgggtctccaggca
tatttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggaggaattactgaa
acgatcttggtggaactggaaatcatgtctcctctgggcatctctgtgtttcgctgtgtt
cggctcttgagaattttcaaagtgaccaggcactggacctccctgagcaacttggtggca
tccttgttaaactccatgaagtccatcgcttcgctgctgcttctgctttttctcttcatc
atcatcttttccttgctggggatgcagctgttcggcggcaagtttaattttgacgaaacg
caaaccaagcggagcacctttgataatttccctcaagcgcttctaacggtgttccagatc
ctgacaggtgaagactggaacgctgtgatgtacgacggcattatggcgtacgggggcccg
tcgtcttcgggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaactat
attctactgaatgtcttcttggccatcgctgtagacaatttggcagatgctgaaagtttg
aatactgctcagaaagaggaagctgaagaaaaggaaagaaagaagattgccagaaaagaa
agcctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgacaac
aaggtcaccgtcgatgactaccgagaagaggatgaggacaaagacccctacccgccttgt
gatgtgccagtaggtgaagaggaagaggaggaggaagaggatgaacccgaggttcctgct
ggaccccgtcctcgaagaatgtctgagttgaacatgaaagagaaaatcacccccatcccc
gaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccacaag
ctcatcaaccaccacatcttcaccaaccttatcctcgtcttcatcatgctgagcagcgct
gccctcgccgccgaggaccccatccgcagccactccttccggaacactatactgggttac
tttgactatgctttcacagccatctttactgttgaaatcctgttaaagatgacgactttt
ggagctttcctccacaaaggggctttctgcaggaactatttcaatttactggatatgctg
gtcgttggggtgtctctggtgtcatttgggatccaatccagtgccatctctgttgtgaag
atcctgagagtcttaagggttctgagaccgctcagggcaatcaacagagcaaaaggactt
aagcacgtggtccagtgcgtctttgtggccatccggacaattggcaacatcatgatcgtc
accaccctcctccagttcatgtttgcctgcatcggggtgcagctcttcaagggaaagttt
tatcgatgcacagatgaagccaagagtaaccccgaagaatgcagggggctcttcatcctc
tacaaggatggggatgtcgataaccccgtggtccgtgagaggatctggcaaaacagcgac
ttcaactttgacaacgtcctctcagctatgatggctctgttcacagtctccacgttcgag
ggctggcccgcgttgctgtacaaagccattgactcgaacggcgagaacgtcggccccatc
tacaactaccgcgtggagatctccgtcttcttcatcatctacatcatcatcgtggcattc
ttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggggagaaa
gagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttgaaa
gcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtg
gtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactacgagcagtccaagatgtttaatgacgccatggacatcctgaac
atggtctttaccggggtgttcactgtcgagatggttttgaaagtcattgcatttaaacct
aaggggtactttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagcatt
gtagacgtggcgctcagcgaagctgacccaactgaaagtgaaaatgtccctgtcccaact
gctacacctgggaactctgaagagagcaatagaatctccatcacctttttccgtcttttc
cgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacactgctgtgg
acttttattaagtccttccaggcgctcccgtatgtcgcccttctcatcgccatgctgttc
ttcatctatgcggttatcggcatgcagatgtttgggaaagttgccatgagagataacaac
cagatcaacaggaacaacaatttccagacctttccccaggcagtactgctgctcttcagg
tgtgcgacgggggaggcctggcaggaaatcatgctggcctgcctcccgggaaagctctgt
gaccccgagtctgattacaaccccggggaggagtacacctgtgggagcaactttgccatt
gtttatttcatcagtttttacatgctctgcgcatttctgatcatcaacctgtttgtggct
gtcatcatggacaatttcgattatctgacccgggactggtctattctggggcctcaccat
ttagacgaattcaaaagaatatggtccgaatatgaccccgaggcaaagggaagaatcaag
cacctggacgtggtcactctgctccgccgcatccagcccccactggggtttgggaaattg
tgtccacacagggtagcctgcaagaggctagttgccatgaacatgccgctcaacagtgat
gggacagtcatgtttaatgcaactctctttgccttggtccgaacggctcttaaaatcaag
acggaagggaacctagaacaagctaatgaagaactccgagctgtgatcaagaaaatctgg
aagaaaaccagcatgaaactacttgaccaagttgtccctccagctggtgatgatgaggta
accgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaa
cggaaagaacaaggactggtgggaaaataccccgcgaagagcagcacaattgccctacag
gcgggattaaggacactgcacgacattgggccagaaatccggcgtgctatatcatgtgac
ttgcaagacgacgagccggaggaaagtaaaggcaaagaagaaggagatgtgttcaaaaga
aatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattccctt
cagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaataatgcc
aatatgtccaaagctgcccctggaaaacggcccagcattgggaaccttgagcatgtgtct
gaaaatgggcatcattccttccacaagcatggccgtgagcctcaaagaaggtccagtatt
aaaagaacgcgctattatgaaacttacattaggtctgactcaggagatgagcagttccca
actatttgccgggaagacccagagatacacggctacttccgggacccctgctgcttgggg
gaacaggagaacttcagcagcgaggagtgctacgaggacgacagctcgcccaccgggagc
aggcagagctacagctgtggctactatacccgatacccaggcagcagcttggacttcgag
cggcctcgaggctaccatcacccgcaaagcttctccgaggatgatgactcacctgtttgc
tatgattcccggaggtctccaaggagacgcctgctccctcccaccccaacatccccccgg
agatcctccttcaacttcgagtgcctgcgccggcacagcagccaggaggaggtcccgcca
tcccccgccttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatcatg
gcagtcgccggcctagattccagtaaggcccagaagtactcgccgagccactccaccagg
tcgtgggccaccccgccagcgaccccgtcgtacagggactggacgccatgctacacccca
ctgatccaggtcgagcggtcggaggccacggaccaggtcaacggcagcctaccgtccctg
caccgcagctcgtggtacacggacgagcccagcgtctcctatcggacgttcacaccagcc
agcctgaccgtccccagaagcttccacaacaaaaacagcgacaagcagaggagcgcagac
agcttggtggaggcggttctgatatccgaaggcttagggcggtatgcgagggacccaaaa
ttcgtgtcagcgacaaaacatgaaatcgccgatgcctgtgacctaaccatcgacgagatg
gagagtgcagccagcaacctgctgaacggcaacgtgcatccccgggccaatggggccgtg
gggcccgtctcacgccggcaggactacgagctccaggacttcgggcccggctacagcgac
gaggagccagaccccgggagggatgaggaggacctggcggatgaaatgatttgcatcacc
accctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (50)   
   KEGG ORTHOLOGY (1)   
   RefGene (46)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (100)   

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