KEGG   Lipotes vexillifer (Yangtze River dolphin): 103078350
Entry
103078350         CDS       T03090                                 
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4-like isoform X1
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04020  Calcium signaling pathway
lve04151  PI3K-Akt signaling pathway
lve05014  Amyotrophic lateral sclerosis
lve05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103078350 (ERBB4)
   04012 ErbB signaling pathway
    103078350 (ERBB4)
   04020 Calcium signaling pathway
    103078350 (ERBB4)
   04151 PI3K-Akt signaling pathway
    103078350 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103078350 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103078350 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lve01001]
    103078350 (ERBB4)
Enzymes [BR:lve01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103078350 (ERBB4)
Protein kinases [BR:lve01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   103078350 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Haspin_kinase DUF3951 ABC1 APH
Other DBs
NCBI-GeneID: 103078350
NCBI-ProteinID: XP_007470071
UniProt: A0A340Y8S3
Position
Unknown
AA seq 1308 aa
MKLATGLWVWVSLLVATGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCNGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
VNQRIVIRDNRKAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRHFSRGRTCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYLWTGHSTLPQHARTPLIAAGVIGG
LFIMVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPMP
YRATTSTIPEAPVAQGATAEIFDDSCCNGTLRKSVAPHVQEDSSTQRYSADPTVFAPERS
PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASHGPPKAED
EYVNEPLYLNTFANTLGNAEYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ
EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgaagctggcgacaggactgtgggtctgggtgagccttctcgtggcgacggggaccgtc
cagcccagcgcttctcagtcagtgtgcgcaggaacagagaataagttgagttctctctct
gacctggaacagcagtaccgagccttgcgcaaatactatgagaactgtgaggtagtcatg
ggcaacctggagataaccagcatcgagcacaaccgggacctctcttttctgcggtctata
agagaagtcacaggctatgtgttggtggctcttaatcagtttcgctatctgcctctggag
aatttacgcattattcgtgggacaaaactttatgaagatcgatatgccttggcaatattt
ttaaactacagaaaagatggaaactttggacttcaagaacttggattgaagaacttgact
gaaatcctaaatggtggagtctatgtagaccagaacaagtttctttgttatacagacaca
attcattggcaagatattgttcggaatccatggccttccaacctgactctggtgtcaaca
aatggtagctcaggatgtggacgttgccataagtcctgcaatggccgatgctggggaccc
acagaaaatcattgtcagactttgacaaggactgtctgtgcagaacagtgtgatggcaga
tgctatggaccctacgttagtgactgctgtcaccgagaatgtgctggaggctgctcggga
cctaaggataccgactgctttgcctgcatgaacttcaatgatagtggagcatgtgttact
cagtgtccacaaactttcgtctacaatccaacaacctttcaactggagcataacttcaat
gcaaaatacacctatggagcattttgtgtcaagaagtgcccacataacttcgtggtcgat
tccagttcctgtgtgcgtgcctgccctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgtactgacatttgcccaaaagcttgtgatggcattggcacagga
tcactgatgtcagctcagaccgtggattctagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttcctagtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaacgtgtttcggacagtccgagagataacaggg
ttcttgaacatacaatcatggcccccaaacatgactgacttcagtgttttttctaacctg
gtgaccattggtggaagagtactctatagtggcctttccttgcttatcctcaagcaacag
ggcatcacttctctgcaattccaatccctgaaggaaatcagtgcaggaaacatctatatc
actgacaacagcaacctgtgttattatcataccattaactggacaacgctcttcagcaca
gtcaaccagagaatagtgatccgggacaacaggaaagctgaaaactgtactgctgaagga
atggtgtgcaaccatctctgttcaaacgatgggtgttggggacctgggccagaccagtgc
ctgtcgtgccgtcacttcagcaggggaaggacctgcatagagtcttgtaacctctatgac
ggtgaatttcgggagtttgagaatggctccatctgtgtggagtgtgacccccagtgtgag
aagatggaagatggtatcctcacatgccatggaccgggacctgacaactgtacaaagtgc
tcccattttaaggatggcccgaactgtgtggaaaaatgtccagatggcttacagggggca
aacagtttcattttcaagtatgctgatcaggatcgggagtgccacccatgccatccaaac
tgcacccaagggtgtagcggtcccactagtcatgactgcatttactacctttggacgggc
cattccactttaccacaacatgctaggactcctctaattgcagccggagtcattggcggg
ctcttcatcatggtcatcgtgggtctaacatttgcagtttatgttagaaggaagagcatc
aaaaagaaaagagccttaagaagattcctggaaacagagttggtagaacccttaacaccc
agtggtacggcgcctaatcaagctcaactacgtattttgaaagaaactgagctcaaaaga
gtaaaagtacttggttcaggtgcttttggaactgtttataaaggtatttgggtccctgaa
ggagaaacagtgaagattcctgtggctattaagattcttaatgaaacaactggtcccaaa
gccaatgtggagtttatggatgaagctctgatcatggcaagtatggaccatccacactta
gtccggttattgggtgtgtgtctaagcccaaccattcagctggttacacagcttatgccc
catggctgcctgttggattatgtccatgaacacaaggataacattggatcccagctattg
cttaattggtgtgtccagatagctaagggaatgatgtacctggaagaaagaaggcttgtt
catcgggatttggcagcccgtaatgtcttagtgaaatctccaaaccatgtaaaaatcaca
gattttggactagccaggctcttggaaggtgatgaaaaagagtataatgctgatggagga
aagatgccaattaaatggatggctttggagtgtatacactatagaaaattcacccatcag
agtgacgtttggagctatggagtcactatatgggaactgatgacctttggaggaaaaccc
tatgatggaattccaaccagagaaatccccgatttgttagagaaaggagaacgtttgccc
cagcctcccatctgcactattgatgtttatatggtcatggtcaaatgttggatgattgat
gctgacagtagacctaaatttaaggaactggctgctgaattttcgaggatggctcgagac
cctcaaagatacctagttattcagggtgatgatcgtatgaagcttcccagtccaaacgac
agcaagttctttcagaatctcttggatgaagaggatttagaagatatgatggatgctgag
gaatatctggtccctcaggctttcaacatcccacctcccatctatacttccagagcaaga
atcgactcaaataggagtgaaattggacacagccctcctcctgcctacacccccatgtca
ggaaaccagtttgtgtaccgagatgggggttttgctgcagagcaaggagtgcccatgccc
tatagggcaaccaccagcacgatcccagaagccccagttgctcagggggctactgccgag
atttttgatgactcctgctgtaatggcaccttacgcaagtccgtggcaccccacgtccaa
gaggacagcagcacgcagaggtacagcgctgaccccacagtgtttgccccagaacggagc
ccacgaggagagctggatgaggaaggttacatgacccctatgcgagacaaacccaaacaa
gaatacctgaaccctgtggaagagaacccttttgtctctcggaggaaaaatggagacctt
caagctttggataatcccgaatatcacagtgcttcccatggtccacccaaggcagaggat
gagtatgtgaatgagccactgtacctcaacacctttgccaacaccttggggaacgctgaa
tacctgaagaacaacgtactgtctgtgccagagaaggccaagaaagcattcgacaaccct
gactactggaaccacagcctgccacctcggagcacccttcagcacccagactatctgcag
gagtacagcacaaaatatttttataaacaaaatggaaggatccggcctattgtggcagag
aatcctgaatacctctctgagttctcgctgaagccaggcactgtgctgcctcctccgccc
tacagacaccggaatactgtggtgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (11)   
   Pfam (11)   
All databases (53)   

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