KEGG   Lipotes vexillifer (Yangtze River dolphin): 103085622Help
Entry
103085622         CDS       T03090                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:lve00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    103085622 (INSR)
   04015 Rap1 signaling pathway
    103085622 (INSR)
   04010 MAPK signaling pathway
    103085622 (INSR)
   04066 HIF-1 signaling pathway
    103085622 (INSR)
   04068 FoxO signaling pathway
    103085622 (INSR)
   04072 Phospholipase D signaling pathway
    103085622 (INSR)
   04022 cGMP - PKG signaling pathway
    103085622 (INSR)
   04151 PI3K-Akt signaling pathway
    103085622 (INSR)
   04152 AMPK signaling pathway
    103085622 (INSR)
   04150 mTOR signaling pathway
    103085622 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    103085622 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103085622 (INSR)
   04923 Regulation of lipolysis in adipocyte
    103085622 (INSR)
   04913 Ovarian Steroidogenesis
    103085622 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103085622 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    103085622 (INSR)
   04213 Longevity regulating pathway - multiple species
    103085622 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103085622 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    103085622 (INSR)
   04931 Insulin resistance
    103085622 (INSR)
Enzymes [BR:lve01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103085622 (INSR)
Protein kinases [BR:lve01001]
 Tyrosine protein kinases
  InsR family [OT]
   103085622 (INSR)
Enzyme-linked receptors [BR:lve01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   103085622 (INSR)
Cytokine receptors [BR:lve04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   103085622 (INSR)
CD molecules [BR:lve04090]
 Proteins
  103085622 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1382 aa AA seqDB search
MGAGGGRGAAAVPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGAAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFFLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQEEDGELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDTRPSRKRRALGDVGNVTAAVPTIPAF
PNTSSTSAPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV
SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGFLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDELHPSFPEVSFFHSEENKVPESEELEME
FEDMESVPLDRSSHAQREEAGGRDGGSALGLKRNYQEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggcgggcggggggcggcggccgtgccactgctggtggccgtcgccgcg
ctgctggtgggcgccgcgggccacctgtaccctggagaggtgtgccccggcatggatatc
cggaataacctcacccggctgcacgagctggccaactgctcggtcatcgaaggacatttg
cagatcctattgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaag
ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcccgcctcttctttaactacgcgctg
gtcatcttcgagatggttcacctgaaggagcttggcctctacaacttgatgaacattacc
cggggctccgttcgcatcgagaagaacaatgaactctgctacctggccactatcgactgg
tctcgcatcctggattccgtggaggataattacatcgtgctgaacaaagacgacaatgag
gagtgtggggacatttgtccaggcgctgcgaagggcaagaccaactgccctgccaccgtc
atcaacgggcaatttgtggagcggtgttggacgcacagccactgccagaaagtgtgtccg
accatctgtaagtctcacggctgcaccgctgagggtctctgttgccacagtgagtgcttg
ggcaactgctctgagcctgacgaccccaccaagtgtgtggcctgtcgcaactttttcctg
gatggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgt
gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcagggc
tgccaccagtatgtcattcacaataacaagtgcatccctgagtgcccctccgggtacacg
atgaattccagcaacttgatgtgcactccatgcctgggcccctgtcccaaggtgtgccac
ctgctggaaggcgagaagaccattgactcagtgacatctgcccaggagctccgaggctgc
accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag
ctagaggccaaccttggactcattgaagaaatttcagggtatctgaaaatccgccgatca
tatgccctcgtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg
gaaatcgggaactactctttctatgccttggacaaccagaacctaaggcagctgtgggac
tggagcaaacacaacctcaccatcactcaggggaaacttttcttccactataatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
agaaacgacattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgaattactt
aaattttcttacattcggacgtcttatgacaagatcttgctgaaatgggagccatattgg
ccccccgacttccgagaccttctggggtttatgcttttctacaaagaggccccttatcag
aacgtgacggagtttgatgggcaggatgcatgtggctccaacagctggaccgtggtggat
attgacccacctatgaggtccaacgaccccaagtcacagaaccaccccgggtggctaatg
cgtggtctcaagccctggacccagtacgccatctttgtcaagaccttggtcaccttttct
gatgaacgccgcacatacggggccaagagcgacatcatctatgtccagacagatgccact
aatccttctgtccccctggatcccatctcggtgtctaattcttcgtcccagattattctg
aagtggaagcctccctctgaccccaatggcaacatcacacactacttggtattctgggag
agacaggaggaagacggtgaactgtatgaattagattattgcctcaaagggttgaagctg
ccctcccggacctggtctccaccgttcgagtctgaggggtcccagaagcacaatcagagt
gagtacgaagagtctgccggtgaatgctgttcctgcccgaagaccgactctcagatcctc
aaggagttggaggagtcctcattcaggaaaacattcgaagattacctgcacaatgtcgtt
ttcatccccagaaaatcctcttcaggccctgttgccgaggacactaggccgtcgaggaaa
cgcagggcccttggtgatgtggggaatgtgacagcggccgtgcccaccattccggcattc
cccaatacgtcctcaaccagcgcacctacgagctcagaggagcacagaccattcgagaaa
gtggtgaacaaggagtctctggtcatctctggcctgcgtcactttactggctatcgcatt
gagctgcaggcttgcaaccaagattcccccgaggagaggtgcagtgtggctgcatatgtc
agtgccaggaccatgcccgaagccaaggcagatgatattgttggccccgtgacccacgaa
atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaacggtctg
attgtgctgtacgaagtgagttatcgacgatacggcgaagaggagctgcacctctgcgtc
tcccgcaggcattttgctctggagcggggctgcaggctgcgtggtctgccacccgggaat
tacagtgtgcgagttcgggccacctccctggcgggcaatggctcctggacggaagccacc
tatttctacgtcacagactatttagacgtgccatcaaatattgcaaaaattatcatcggc
cctctcatctttgtctttctcttcagtgtcgtgatcggaagtatttatctgttcctgaga
aagaggcagccggatgggccactgggaccactgtatgcttcttcaaaccccgagtacctc
agtgccagcgatgtgtttccctgctctgtgtacgtgccggatgagtgggaggtgcctcga
gagaagatcacgctcctgcgagaactggggcagggctccttcggcatggtgtacgagggc
aacgccagggacattgtcaagggcgaggcggagacccgagtggcggtgaagacggtcaac
gagtctgccagcctgcgagagcggatcgaatttctcaacgaggcctcggtcatgaagggc
ttcacctgccaccatgtggtccgcctcctgggggtggtatccaaaggccagccgacgctg
gtggtgatggagttgatggctcatggggacttgaagagctacctccgttccctgcggcct
gaggccgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggct
gcggagatcgccgacgggatggcatacctgaacgccaagaagtttgtacaccgggacctc
gcagctcgaaactgcatggttgcccacgattttaccgtcaaaattggagactttggaatg
accagagacatctacgaaacggattactaccggaaagggggaaagggtctgctccccgtg
cggtggatggcacccgaatcgctgaaggacggggtctttaccacttcttcggacatgtgg
tcctttggcgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggccta
tcaaatgagcaggtgttaaaatttgtcatggatggagggtttctggatcaacccgacaac
tgtcctgagagagtcaccgacctgatgcgcatgtgctggcagttcaaccccaagatgcgg
ccgaccttcctggaaattgtcgacctgctcaaggacgagctgcacccaagttttcccgaa
gtttccttcttccacagcgaggagaacaaggtgcccgagagcgaggagctggagatggaa
tttgaggacatggagagtgtccccctggaccggtcctcacatgcgcagagggaggaggcc
gggggccgggatggagggtccgcactggggctaaagagaaactatcaggaacacatcccc
tacacccacatgaacgggggcaagaaaaacggacgcattctgactctgccccggtctaat
ccttcctaa

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