KEGG T05070: BHM04

Macrococcus sp. IME1552: BHM04_12245

Entry

BHM04_12245       CDS       T05070

Name

(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase

K01929

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]

Organism

macr Macrococcus sp. IME1552

Pathway

macr00300

Lysine biosynthesis

macr00550

Peptidoglycan biosynthesis

macr01100

Metabolic pathways

macr01502

Vancomycin resistance

Brite

KEGG Orthology (KO) [BR:macr00001]
09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    BHM04_12245
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    BHM04_12245
09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    BHM04_12245
Enzymes [BR:macr01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     BHM04_12245

SSDB

Motif

Pfam:

Mur_ligase_M Mur_ligase Mur_ligase_C

Other DBs

NCBI-ProteinID:

ATD31911

Position

2364054..2365391

AA seq 445 aa
MIKRNLQWIAEQTNGTVKGYHDVMIDGVSIDSRHINEDVLFIPFKGEHVDGHQYVAQAIE
SGAAAALWQSDAPNMPVGLPLVVVDDTLSALQAIGKAYLEEVNPKVIAITGSNGKTSTKD
MVEIVLAPNFKVKKTQGNYNNEIGLPITLCQLDEDTEISILEMGMSGFGEIAFLSNLVQP
DIAAITNIGESHMRDLGSRAGIAQAKFEITEGLKGPLFYDGDEPLLNELVDNTDGHYKSI
GFNQVNDFYIHDLQASERSIAFKVGEAQFSIPTLGAHNARNATIAIAIGRLLGLSDAVIN
DNLGHLHLTNMRMEQIIGQNKTRLINDAYNASPTSMRASIDTLSIMDVPTKIIVFSDVLE
LGPDSKMYHEAVGAYFENKSIDHLFTVGTEAKYIHDKAQDFTNAMHFETKEALEEALIPY
LNPETVILFKASRGMALETIINHLI

NT seq 1338 nt +upstreamnt +downstreamnt
atgataaaaagaaatttacaatggattgcagaacaaacgaatggcactgtaaaagggtat
catgatgtgatgatcgatggcgtatcgattgattcaagacatattaatgaggatgtattg
tttattccttttaaaggtgagcatgttgatggacatcaatatgtagcgcaagcaatagaa
agtggtgctgcagctgctttatggcaaagtgatgcaccaaacatgcctgtagggttaccg
ctagttgtagtcgatgatactttaagtgcattacaggcaatcggtaaagcttatttagaa
gaagtaaacccgaaagttattgcgattacaggaagtaatggtaaaacttctacaaaagat
atggtggaaattgttctggcaccgaattttaaagttaagaagacacaaggcaactacaat
aatgaaattggactgccgattacactgtgtcaattagatgaagatactgaaatatctata
ttagagatgggtatgtcggggtttggtgagattgcatttttatcaaatctcgtacaacct
gatattgctgcgattactaatattggcgaaagtcatatgcgtgacttaggctcaagagct
ggtatcgcacaagccaagtttgaaattactgagggattaaagggtccattattttatgat
ggcgatgaaccattattaaatgaattggtagataatactgatggtcactataaaagtatc
ggctttaatcaggttaacgatttttacattcatgacttacaagcatctgaaagaagcatt
gcttttaaagtgggggaagcgcaatttagcattccgacgcttggtgcacataatgcccga
aatgcaacgatcgcgattgcgattggtcgtttacttggattaagtgacgcagtaatcaat
gataatttaggacatctgcatttaacaaatatgcgcatggaacaaattattgggcagaat
aagacccgtttaatcaatgacgcgtataatgcaagtccgacgagcatgcgtgcttctatt
gatacgttatcaattatggatgtaccgacgaagattatcgtatttagcgatgtgttagaa
ctcggtcctgattcaaagatgtatcatgaagcagtaggtgcttatttcgaaaataaatcg
attgatcatttatttacagtcggtactgaagcaaaatacattcatgataaagcacaagat
ttcacgaatgctatgcattttgaaacgaaagaagcgcttgaagaagcactaataccatat
ttaaatccagagacggttatactatttaaagcaagccgcggcatggcgcttgaaacgatt
attaatcatttgatataa

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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