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Entry
map00062                    Pathway                                

Name
Fatty acid elongation
Class
Metabolism; Lipid metabolism
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Pathway map
Fatty acid elongation
map00062

All organismsOrtholog table
Module
M00085  
Fatty acid biosynthesis, elongation, mitochondria [PATH:map00062]
M00415  
Fatty acid biosynthesis, elongation, endoplasmic reticulum [PATH:map00062]
Disease
H00149  
Neuronal ceroid lipofuscinosis
H00186  
Hyperargininemia
H00810  
Progressive myoclonic epilepsy (PME/ EPM)
H00819  
Stargardt disease (STGD)
H01364  
3-Hydroxyacyl-CoA dehydrogenase deficiency
Reference
PMID:4387390
  Authors
Seubert W, Lamberts I, Kramer R, Ohly B
  Title
On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA.
  Journal
Biochim Biophys Acta 164:498-517 (1968)
Reference
PMID:7150615
  Authors
El-Fakhri M, Middleton B
  Title
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria.
  Journal
Biochim Biophys Acta 713:270-9 (1982)
Reference
PMID:8190743
  Authors
Cassagne C, Lessire R, Bessoule JJ, Moreau P, Creach A, Schneider F, Sturbois B
  Title
Biosynthesis of very long chain fatty acids in higher plants.
  Journal
Prog Lipid Res 33:55-69 (1994)
Reference
  Authors
Jakobsson A, Westerberg R, Jacobsson A.
  Title
Fatty acid elongases in mammals: their regulation and roles in metabolism.
  Journal
Prog Lipid Res 45:237-49 (2006)
Reference
  Authors
Blacklock BJ, Jaworski JG
  Title
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.
  Journal
Biochem Biophys Res Commun 346:583-90 (2006)
Reference
  Authors
Shepherd T, Wynne Griffiths D
  Title
The effects of stress on plant cuticular waxes.
  Journal
New Phytol 171:469-99 (2006)
Reference
  Authors
Riezman H
  Title
The long and short of fatty acid synthesis.
  Journal
Cell 130:587-8 (2007)
Reference
  Authors
Raffaele S, Leger A, Roby D
  Title
Very long chain fatty acid and lipid signaling in the response of plants to pathogens.
  Journal
Plant Signal Behav 4:94-9 (2009)
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