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Entry
map00230                    Pathway                                

Name
Purine metabolism
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Purine metabolism
map00230

All organismsOrtholog table
Module
M00005  
PRPP biosynthesis, ribose 5P => PRPP [PATH:map00230]
M00048  
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:map00230]
M00049  
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:map00230]
M00050  
Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:map00230]
M00546  
Purine degradation, xanthine => urea [PATH:map00230]
Disease
H00192  
Xanthinuria
H00194  
Lesch-Nyhan syndrome
H00195  
Adenine phosphoribosyltransferase deficiency
H00196  
Phosphoribosylpyrophosphate synthetase I superactivity
H00197  
Adenylosuccinate lyase deficiency
H00469  
Mitochondrial DNA depletion syndrome (MDS)
H00481  
Cone-rod dystrophy and cone dystrophy
H00494  
Desbuquois syndrome
H00674  
Anemia due to disorders of nucleotide metabolism
H00761  
SEMD, Pakistani type
H00824  
Calcification of joints and arteries
H00837  
Leber congenital amaurosis (LCR)
H00946  
Arts syndrome
H00966  
AICA-ribosiduria
H01002  
Generalized arterial calcification of infancy
H01096  
Pyruvate kinase (PK) deficiency
H01118  
Progressive external ophthalmoplegia (PEO)
H01128  
Reticular dysgenesis
H01394  
Cole disease
Other DBs
GO: 
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
KO pathway
 

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