| Entry |
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| Name |
Purine metabolism
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| Class |
Metabolism; Nucleotide metabolism
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| Pathway map |
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| Module |
| PRPP biosynthesis, ribose 5P => PRPP [PATH: map00230] | | Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: map00230] | | Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: map00230] | | Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: map00230] | | Purine degradation, xanthine => urea [PATH: map00230] |
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| Disease |
| Xanthinuria | | Lesch-Nyhan syndrome | | Adenine phosphoribosyltransferase deficiency | | Phosphoribosylpyrophosphate synthetase I superactivity | | Adenylosuccinate lyase deficiency | | Mitochondrial DNA depletion syndrome (MDS) | | Cone-rod dystrophy and cone dystrophy | | Desbuquois syndrome | | Anemia due to disorders of nucleotide metabolism | | SEMD, Pakistani type | | Calcification of joints and arteries | | Leber congenital amaurosis (LCR) | | Arts syndrome | | AICA-ribosiduria | | Generalized arterial calcification of infancy | | Pyruvate kinase (PK) deficiency | | Progressive external ophthalmoplegia (PEO) | | Reticular dysgenesis |
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| Other DBs |
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| Reference |
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| Authors |
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J. |
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| Title |
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli. |
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| Journal |
J Bacteriol 181:7479-84 (1999) |
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| Reference |
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| Authors |
Xi H, Schneider BL, Reitzer L. |
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| Title |
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage. |
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| Journal |
J Bacteriol 182:5332-41 (2000) |
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| KO pathway |
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