| Entry |
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| Name |
Tyrosine metabolism
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| Class |
Metabolism; Amino acid metabolism
 |
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| Pathway map |
  |
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| Module |
| Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: map00350] | | Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: map00350] | | Tyrosine degradation, tyrosine => homogentisate [PATH: map00350] | | Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: map00350] |
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| Disease |
| Alkaptonuria | | Tyrosinemia | | Oculocutaneous albinism (OCA) | | Thyroid dyshormonogenesis | | Brunner syndrome | | Primary dystonia | | Dopamine beta-hydroxylase deficiency | | Aromatic L-amino acid decarboxylase (AADC) deficiency |
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| Drug |
| Nepicastat hydrochloride (USAN) |
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| Other DBs |
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| Reference |
|
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| Authors |
Prieto MA, Diaz E, Garcia JL. |
|---|
| Title |
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster. |
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| Journal |
J Bacteriol 178:111-20 (1996) |
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| Reference |
|
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| Authors |
Sparnins VL, Dagley S. |
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| Title |
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases. |
|---|
| Journal |
J Bacteriol 124:1374-81 (1975) |
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| Reference |
|
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| Authors |
Ito S, Wakamatsu K |
|---|
| Title |
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. |
|---|
| Journal |
Photochem Photobiol 84:582-92 (2008) |
|---|
| Reference |
|
|---|
| Authors |
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC |
|---|
| Title |
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase. |
|---|
| Journal |
Biochem J 354:131-9 (2001) |
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| KO pathway |
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