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Entry
map00564                    Pathway                                

Name
Glycerophospholipid metabolism
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
Glycerophospholipid metabolism
map00564

All organismsOrtholog table
Module
M00090  
Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:map00564]
M00091  
Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:map00564]
M00092  
Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:map00564]
M00093  
Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:map00564]
Disease
H00158  
Lecithin:cholesterol acyltransferase deficiency
H00207  
Rhizomelic chondrodysplasia punctata
H00654  
Barth syndrome (BTHS)
H00770  
Congenital myasthenic syndrome
H00833  
Neurodegeneration with brain iron accumulation (NBIA)
H01117  
Majeed syndrome
H01290  
Acute recurrent myoglobinuria
Other DBs
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
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