| Entry |
|
|---|
| Name |
Biosynthesis of unsaturated fatty acids
|
|---|
| Class |
Metabolism; Lipid metabolism
 |
|---|
| Pathway map |
| Biosynthesis of unsaturated fatty acids |
  |
|---|
| Disease |
| Peroxisomal beta-oxidation enzyme deficiency |
|
|---|
| Reference |
|
|---|
| Authors |
Jakobsson A, Westerberg R, Jacobsson A. |
|---|
| Title |
Fatty acid elongases in mammals: their regulation and roles in metabolism. |
|---|
| Journal |
Prog Lipid Res 45:237-49 (2006) |
|---|
| Reference |
|
|---|
| Authors |
Moon YA, Horton JD. |
|---|
| Title |
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade. |
|---|
| Journal |
J Biol Chem 278:7335-43 (2003) |
|---|
| Reference |
|
|---|
| Authors |
Han G, Gable K, Kohlwein SD, Beaudoin F, Napier JA, Dunn TM. |
|---|
| Title |
The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase. |
|---|
| Journal |
J Biol Chem 277:35440-9 (2002) |
|---|
| Reference |
|
|---|
| Authors |
Su HM, Moser AB, Moser HW, Watkins PA. |
|---|
| Title |
Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis. |
|---|
| Journal |
J Biol Chem 276:38115-20 (2001) |
|---|
| Reference |
|
|---|
| Authors |
Huyghe S, Mannaerts GP, Baes M, Van Veldhoven PP. |
|---|
| Title |
Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model. |
|---|
| Journal |
Biochim Biophys Acta 1761:973-94 (2006) |
|---|
| Reference |
|
|---|
| Authors |
Denic V, Weissman JS. |
|---|
| Title |
A molecular caliper mechanism for determining very long-chain fatty acid length. |
|---|
| Journal |
Cell 130:663-77 (2007) |
|---|
| KO pathway |
|
|---|
