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Entry
map01040                    Pathway                                

Name
Biosynthesis of unsaturated fatty acids
Class
Metabolism; Lipid metabolism
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Biosynthesis of unsaturated fatty acids
map01040

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Disease
H00407  
Peroxisomal beta-oxidation enzyme deficiency
Reference
  Authors
Jakobsson A, Westerberg R, Jacobsson A.
  Title
Fatty acid elongases in mammals: their regulation and roles in metabolism.
  Journal
Prog Lipid Res 45:237-49 (2006)
Reference
  Authors
Moon YA, Horton JD.
  Title
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
  Journal
J Biol Chem 278:7335-43 (2003)
Reference
  Authors
Han G, Gable K, Kohlwein SD, Beaudoin F, Napier JA, Dunn TM.
  Title
The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase.
  Journal
J Biol Chem 277:35440-9 (2002)
Reference
  Authors
Su HM, Moser AB, Moser HW, Watkins PA.
  Title
Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis.
  Journal
J Biol Chem 276:38115-20 (2001)
Reference
  Authors
Huyghe S, Mannaerts GP, Baes M, Van Veldhoven PP.
  Title
Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model.
  Journal
Biochim Biophys Acta 1761:973-94 (2006)
Reference
  Authors
Denic V, Weissman JS
  Title
A molecular caliper mechanism for determining very long-chain fatty acid length.
  Journal
Cell 130:663-77 (2007)
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