KEGG   Macaca mulatta (rhesus monkey): 678688Help
Entry
678688            CDS       T01028                                 

Gene name
CYP2E1
Definition
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)
Orthology
K07415  
cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Steroid hormone biosynthesis
Arachidonic acid metabolism
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Metabolic pathways
Non-alcoholic fatty liver disease (NAFLD)
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    678688 (CYP2E1)
   00590 Arachidonic acid metabolism
    678688 (CYP2E1)
   00591 Linoleic acid metabolism
    678688 (CYP2E1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    678688 (CYP2E1)
   00982 Drug metabolism - cytochrome P450
    678688 (CYP2E1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    678688 (CYP2E1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    678688 (CYP2E1)
Enzymes [BR:mcc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     678688 (CYP2E1)
Cytochrome P450 [BR:mcc00199]
 Cytochrome P450, animal type
  CYP2 family
   678688 (CYP2E1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
9
AA seq 493 aa AA seqDB search
MSALGVSVALLVWVAVLLLVSIWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL
AQRFGPVFTLYVGSRRVVVVHGYKAVREVLLDHKDEFSGRGDIPAFHAHRDRGIIFNNGP
TWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI
ADILFRKHFDYNDEKFLRLMYLFNENFQLLSTPWLQLYNNFPSLLHYLPGSHRKVMKNVA
EIKEYVSERVKEHLQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAG
TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRF
ITLVPSNLPHEATRDTIFRGYIIPKGTVIVPTLDSVLYDNQEFPDPEKFKPEHFLDESGK
FKYSDYFKPFSAGKRVCAGEGLARMELFLLLSAILQHFNLKPLVDPKDIDISPVNIGFGC
IPPRFKLCVIPRS
NT seq 1482 nt NT seq  +upstreamnt  +downstreamnt
atgtctgccctcggagtcagcgtggccctgttggtgtgggtggccgtcctcctgctggtg
tccatctggaggcaggtgcacagcagctggaatctgcccccaggccctttcccacttccc
atcatcgggaacctcttccagttggaattgaagaatattcccaagtccttcacccggctg
gcccagcgcttcgggccggtgttcacgctgtacgtgggctcgcggcgcgtggtggttgtg
cacggctacaaggcggtgagggaagtgctgctggaccacaaggacgagttctcgggcaga
ggcgacatccccgcgttccacgcgcacagggacaggggaattattttcaataacggacct
acctggaaggacatccggcggttttccctgaccaccctccggaactatgggatggggaaa
cagggcaacgagagccggatccagagggaggcccacttcctgctggaagcgctcaggaag
acccaaggccagcctttcgatcccaccttcctcatcggctgtgcgccctgcaacgtcata
gccgacatcctcttccgcaagcattttgactacaatgatgagaagtttctgaggctgatg
tatttgtttaatgagaacttccagctgctcagcactccctggctccagctttacaataat
ttccccagcttactacactacttgcctggaagccatagaaaagtcatgaaaaatgtggct
gaaataaaggagtatgtgtctgaaagggtgaaggagcaccttcaatctctggaccccaac
tgcccccgggatctcactgactgcctgcttgtggaaatggagaaggaaaagcacagtgca
gagcgcttgtacacaatggacggtatcaccgtgactgtggccgacctgttctttgcgggg
acagagaccaccagcaccactctgagatacgggctcctgattctcatgaaataccctgag
atcgaagagaagctccatgaagaaattgacagggtgattgggccaagccgaatccccgcc
atcaaggataggcaagagatgccctatatggatgctgtggtgcatgagattcagcggttc
atcaccctcgtgccctccaacctgccccatgaagcaacccgagacaccattttcagagga
tacatcatccccaagggcacggtcatagtgccaactctggactctgttttgtatgacaac
caagaatttcctgatccagaaaagtttaagccagaacacttcctggatgaaagtgggaag
ttcaagtacagtgactatttcaagccattttccgcaggaaaacgagtgtgtgctggagaa
ggcttggctcgcatggagttgtttctattgttgtctgccattttgcagcattttaatttg
aagcctctcgttgacccaaaggatatcgacatcagtcctgtaaatattgggtttgggtgt
atcccaccacgtttcaaactctgtgtcattccccgttcatga

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