KEGG   Macaca mulatta (rhesus monkey): 695975Help
Entry
695975            CDS       T01028                                 

Gene name
HADHA
Definition
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Orthology
K07515  
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Fatty acid elongation
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Biosynthesis of unsaturated fatty acids
Metabolic pathways
Carbon metabolism
Fatty acid metabolism
Module
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Fatty acid biosynthesis, elongation, mitochondria
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    695975 (HADHA)
   01212 Fatty acid metabolism
    695975 (HADHA)
  Carbohydrate metabolism
   00640 Propanoate metabolism
    695975 (HADHA)
   00650 Butanoate metabolism
    695975 (HADHA)
  Lipid metabolism
   00062 Fatty acid elongation
    695975 (HADHA)
   00071 Fatty acid degradation
    695975 (HADHA)
   01040 Biosynthesis of unsaturated fatty acids
    695975 (HADHA)
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    695975 (HADHA)
   00310 Lysine degradation
    695975 (HADHA)
   00380 Tryptophan metabolism
    695975 (HADHA)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    695975 (HADHA)
Enzymes [BR:mcc01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.211  long-chain-3-hydroxyacyl-CoA dehydrogenase
     695975 (HADHA)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     695975 (HADHA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
13
AA seq 763 aa AA seqDB search
MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK
VNTLSKELHSEFTEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLSACKTLQEVTQLS
QEAQRILEKLEKSPKPVVAAINGSCLGGGLELAISCQYRIATKDRKTVLGVPEVLLGALP
GAGGTQRLPKMVGVPAALDMMLTGRNIRADRAKKMGLVDQLVEPLGPGLKPPEERTMEYL
EEVAITFAKGLADKKISPKRNKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA
PLKIIDVVKTGIEQGSDAGYLSESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD
VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLDRGQQQVFKGLNDKVKKKALTSF
ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP
ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSRDTSASAVAVGLKQGKVIIVVK
DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA
EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK
LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF
VDLYGAQTIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ
NT seq 2292 nt NT seq  +upstreamnt  +downstreamnt
atggtggcctgccgggcaattggcatcctcagccgcttctctgccttcaggatcctccgc
tcccgaggttatatatgccgcaattttacaggatcttctgctttgctgaccagaacccat
attaactatggagtcaaaggggatgtggcagttgttcgaattaactctcccaattcaaag
gtaaatacactaagtaaagagctgcattcagaattcacagaagttatgaatgaaatctgg
gctagtgatcaaatcagaagtgccgtccttatctcatcaaagccaggctgctttattgca
ggtgctgatatcaacatgttatccgcttgcaagacccttcaagaagtaacacagctctca
caagaagcacagagaatattagagaaacttgaaaagtccccaaagcctgttgtggctgcc
atcaatggatcctgcctgggaggaggacttgagcttgccatttcatgccaatacagaata
gcaacaaaagacagaaaaacagtattaggtgtccctgaagtcttgctgggggccttacca
ggagcaggaggcacacaaaggctgcccaaaatggtgggtgtgcctgctgccttggacatg
atgctgactggtagaaacattcgtgcagacagggcaaagaaaatgggattggttgaccaa
ttagtggaacccctgggaccaggactaaaacctccagaggaacggacaatggaataccta
gaagaggttgcaattacttttgccaaaggactagctgataagaagatttctccaaagaga
aacaagggattggtggagaaattgacagcgtatgccatgactattccatttgtcaggcaa
caggtttacaaaaaagtggaagaaaaagtgcgaaagcagactaaaggcctatatcctgca
cctctgaaaataattgatgtggtaaagactggaattgagcaagggagtgatgctggttat
ctctctgaatctcagaaatttggagagcttgtaatgaccaaagaatcaaaggccttgatg
ggactctaccatggtcaggtcctgtgcaagaagaataaatttggagctccacagaaggat
gttaagcatctggctattcttggtgcagggctgatgggagcaggcatcgcccaagtctcc
gtagataaggggctaaagactatacttaaagatgccaccctcactgggctagaccgagga
cagcaacaagtgttcaaaggattaaatgacaaagtgaagaagaaagctctaacatcattt
gaaagggattccatcttcagcaacttgactgggcagcttgattaccaaggttttgaaaag
gccgacatggtgattgaagctgtgtttgaggaccttagtcttaagcacagagtgctaaag
gaagtagaagcggtgattccagatcactgtatctttgccagtaacacatctgctctccca
atcagtgaaattgctgctgtcagcaaaagacctgagaaggtgatcggcatgcactacttc
tctcccgtggacaagatgcagctgctggagattatcacgactgagaaaacttccagagac
accagtgcttcagctgtagcagtcggtctcaagcaggggaaggtcatcattgtggttaag
gatggacctggcttctatactaccaggtgccttgcgcccatgatgtctgaagtcatccga
atcctccaggaaggagttgacccgaagaagctggattccctgaccacaagttttggcttt
cctgtgggtgccgccacactggtggatgaagttggcgtggatgtagcaaaacatgtggcg
gaagatctgggcaaagtctttggggagcggtttggaggcggaaacccagaactgctgaca
cagatggtgtccaagggcttcctaggtcgcaagtctgggaagggcttttacatctatcag
gagggtgtgaagaggaaggatttgaattctgacatggatagtattttagcgagtctgaag
ctgcctcctaagtctgaagtctcctcagatgaagacatccagttccgcctggtgacaaga
tttgtgaatgaggcagtcatgtgcctgcaagaggggatcttggccacacctgcggaggga
gacatcggagccgtctttgggcttggcttcccgccttgtcttggagggcctttccgcttt
gtggatctgtatggcgcccagacgatagtggaccggctcaagaagtatgaagctgcctat
ggaaaacagttcaccccatgccagctgctagctgaccatgctaacagccccaacaagaag
ttctaccagtga

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