| Entry |
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| Gene name |
GCK
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| Definition |
(RefSeq) glucokinase (hexokinase 4)
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| KO |
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| Organism |
mcc Macaca mulatta (rhesus monkey)
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| Pathway |
| Glycolysis / Gluconeogenesis | | Galactose metabolism | | Starch and sucrose metabolism | | Amino sugar and nucleotide sugar metabolism | | Neomycin, kanamycin and gentamicin biosynthesis | | Metabolic pathways | | Carbon metabolism | | Insulin signaling pathway | | Insulin secretion | | Prolactin signaling pathway | | Glucagon signaling pathway | | Type II diabetes mellitus | | Maturity onset diabetes of the young | | Central carbon metabolism in cancer |
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| Module |
| Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | | Nucleotide sugar biosynthesis, glucose => UDP-glucose |
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| Brite |
KEGG Orthology (KO) [BR:mcc00001]
Metabolism
Overview
01200 Carbon metabolism
699728 (GCK)
Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
699728 (GCK)
00052 Galactose metabolism
699728 (GCK)
00500 Starch and sucrose metabolism
699728 (GCK)
00520 Amino sugar and nucleotide sugar metabolism
699728 (GCK)
Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
699728 (GCK)
Organismal Systems
Endocrine system
04911 Insulin secretion
699728 (GCK)
04910 Insulin signaling pathway
699728 (GCK)
04922 Glucagon signaling pathway
699728 (GCK)
04917 Prolactin signaling pathway
699728 (GCK)
Human Diseases
Cancers
05230 Central carbon metabolism in cancer
699728 (GCK)
Endocrine and metabolic diseases
04930 Type II diabetes mellitus
699728 (GCK)
04950 Maturity onset diabetes of the young
699728 (GCK)
Enzymes [BR:mcc01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
699728 (GCK)
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| SSDB |
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| Motif |
 |
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| Other DBs |
NCBI-ProteinID: NCBI-GeneID: Ensembl: UniProt: |
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| Position |
3
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| AA seq |
466 aa  
MAMDATRSQAQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG
ELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRP
SATDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ |
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| NT seq |
1401 nt  +upstreamnt +downstreamnt
atggcgatggatgccacaaggagccaggcccagacagccttgactctggtagagcagatc
ctggcggagttccagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaag
gagatggaccgtggcctgaggttggagacccatgaagaggccagtgtgaagatgctgccc
acctacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctg
ggtggcaccaacttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtgg
agcgtgaagaccaaacaccagatgtactccatccccgaggacgccatgaccggcactgct
gagatgctcttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcatgaagacatc
gataagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac
aatgtcgtggggcttctgcgagatgccatcaaacggagaggggacttcgaaatggatgtg
gtggcaatggtgaatgacacggtggccacgatgatctcctgctactacgaagaccatcag
tgcgaggtcggcatgattgtgggcacgggctgcaacgcctgctacatggaggagatgcag
aatgtggagctggtggagggggacgagggccgcatgtgcgtcaacaccgaatggggcgcc
ttcggggactcgggcgagctggacgagttcctgctggagtatgaccgcctggtggacgag
agctctgcaaaccccggtcagcagctgtatgagaagctcataggtggcaagtacatgggc
gagctggtgcggctcgtgctgctcaggctcgtggacgaaaacctgctcttccacggggag
gcctccgagcagctgcgcacacgcggagccttcgagacacgcttcgtgtcgcaggtggag
agcgacacgggcgaccgcaagcagatctacaacatcctgagcacgctggggctacgaccc
tcggccactgactgcgacatcgtgcgccgcgcctgcgagagcgtgtctacgcgcgctgca
cacatgtgctcggcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacgtaatgcgcatcactgtgggcgtggatggctccgtgtacaagctgcaccccagcttc
aaggagcggttccacgctagcgtgcgcaggctgacgcccagctgcgagatcaccttcatc
gagtcggaggagggcagtggccggggcgcggccctggtctcggcggtggcctgtaagaag
gcctgcatgctgggccagtga |
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