KEGG   Macaca mulatta (rhesus monkey): 701758Help
Entry
701758            CDS       T01028                                 

Gene name
PLCE1
Definition
phospholipase C, epsilon 1
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    701758 (PLCE1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    701758 (PLCE1)
   04015 Rap1 signaling pathway
    701758 (PLCE1)
   04020 Calcium signaling pathway
    701758 (PLCE1)
   04070 Phosphatidylinositol signaling system
    701758 (PLCE1)
   04024 cAMP signaling pathway
    701758 (PLCE1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    701758 (PLCE1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    701758 (PLCE1)
Enzymes [BR:mcc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     701758 (PLCE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
9
AA seq 2180 aa AA seqDB search
MTSEEITASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRQSGETSHTISRLNKL
KEEPSGSNLPKILSITREKIVSDENSNEKCWEKSMPDSVKNLNINCNNILRNHQHGLPQR
QFYEMYNSVVEEDLCLETGILSPLERKVFPGIQLELDRPSMGINPLGNQSAIIETGRADP
DSSTAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKENYMAYTCKLMEL
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCQKVDMVCSSHSFCKEDFTDSQTAKTFLSHF
EDFPDNCEDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLIA
WSYIDQKRNGPLLPCGRVMEPLSTVEIKQGGSRRLSEAQWYPIYNAVRRGEETENTVGSL
LHFFTKLPASETAHGRISVGPCLKQCVRDTVYEYRATLQRTSISQYITGSLLEATTSLGA
RSGLLSTFGGSTGRMMLKERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSR
SLETDEEDSPSEGNSSRKSSLKDKSRWHLGSAYIENNLSDIRISLCGKFDILKHVTGTQQ
GCDQDNRGHDEIPDRESCELENRATWVARSLFFCGHLCSSTSWNFLGDINVFTSPLLGAS
YCIHHVVLSQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTLGIS
TTKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEANTIASPPN
PLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGGMKG
FQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLMIDE
NTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIF
GVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKENFAS
KNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWD
GDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFK
TVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASM
QAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCSDKLQFEYSEE
IPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLST
LNASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPT
TSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPI
MFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD
LDSMDPVVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNE
QFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLF
INSRRMEENSSGSPMSASSMFTTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQLL
QQILTTEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEG
YVGRILLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQ
DVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTPKSSQRVLLDQECVFQAQ
SKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQ
TKEEKPVGGLSSSDTMDYRQ
NT seq 6543 nt NT seq  +upstreamnt  +downstreamnt
atgacttctgaagaaattacagcttctgttctcatacctgtgactcagagaaaagtggtt
tctgcccagtcagctgcagatgaaagtagtgaaaaggtctcagacatcaatatttcaaaa
gcacatactgtcagacaaagtggggagacttctcataccatctcacgactgaacaaactt
aaagaagaaccttctggaagcaacttgccaaagattctctcaataacaagggagaaaata
gtgagtgatgagaacagtaatgaaaaatgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacaacatattgagaaaccatcagcatggccttcctcaaaga
cagttttatgaaatgtacaactctgttgttgaggaagacctgtgtttagaaactggaatt
ctgtctccactggaaagaaaggtgttccctggaattcaactggaactagacagaccttcc
atgggcattaatcctttaggaaatcagtcagcaatcatagagacaggcagagcagaccct
gacagcagcacggcagtatttcattttcattatgaagttgacagaagaatgtcagacact
ttctgtaccctatcagaaaacttaattttagacgattgtggaaattgtgtaccactacct
gggggtgaggagaagcaaaaggaaaactacatggcatatacctgtaaactgatggaattg
gccaaaaattgtgataataagaatgaacagctgcagtgtgatcattgtgacaccttgaat
gataaatacttttgctttgaaggctcttgccagaaggtggacatggtatgttcaagtcat
agcttttgtaaggaagattttactgacagtcaaactgccaagacctttttgagtcatttt
gaggatttccctgataattgtgaagatgtagaagaagatgcttttaaaagcaaaaaggag
cggtccactttgttagtcaggagattctgtaaaaatgacagagaagttaagaaatctgtg
tataccggcacaagagcaattgtgaggactctgccttctggccacattgggctgattgca
tggagttacatagatcagaagagaaatggtcccttactgccttgtgggagagtaatggaa
cccctatcaacagtggagataaagcaaggtgggagccgacgtctgtcagaagcccagtgg
tatcctatctacaatgcagtgagaagaggagaagaaacagaaaatacagttggatctcta
ctccatttcttcaccaagctcccagcctccgagacagcccatggaagaataagtgttggt
ccatgcttaaagcaatgtgtccgagacactgtatatgagtatcgcgccaccctccaaagg
acttcaatatcgcagtacatcaccggttctctcctagaagcaaccacatctttgggagca
agaagtggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgc
cagccaggcccctctgtggccaattccaacaccctcccttcaagttcagctgggatcagc
aaggagctgatcgatctgcagcctctcatccagttcccagaggaagtcgccagcatcctg
atggagcaggagcagagtatttaccgcagggtcttgccggtcgactacctttgcttctta
acacgggacttgggcactcccgaatgccagaggtccctgccctgcctcaaagcatccatc
tcagcgtcaattcttaccactcagaatggagagcacaatgcccttgaagatctggtgatg
aggtttaatgaggtgagctcctgggtgacgtggctgatcctcacggcaggctccatggag
gagaagcgagaagtcttttcatatttggtgcatgtggccaagtgctgctggaacatgggc
aactacaacgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatg
tggcagtttatggaccagtctgatattgagaccatgaggagcctgaaggatgctatggcc
cagcatgagtcctcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggc
tgtaaggtggttccgttctgtggagtgtttcttaaggagctctgtgaagtgcttgacggc
gcctctggcctcatgaagatatgcccgcggtacaattcccaagaagaaactttagagttt
gtagcagattacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcggagaaggagtccactgtcaacagcatctttcaggtcatccggagctgcagtcga
agtctggagacagacgaggaggacagccccagtgaagggaacagctccaggaaaagttcc
ttgaaggataaaagccgatggcacttgggaagtgcttatatagaaaataatctttctgac
attagaatttccttatgtggtaaatttgatatattaaagcatgtcactggaactcagcag
ggatgtgaccaagacaacaggggacatgatgaaattcctgacagagaatcttgtgagtta
gaaaacagggccacttgggtggccagatcattattcttctgtggccatctgtgctcttcc
acctcttggaattttctgggagacattaatgtgtttacttccccattgcttggtgcttcc
tattgtattcaccatgtggttctttcacaggaggatggacggtatgaaggcccaactttg
gctcatgctgtggagttgtttggtggcagacgatggagtgctcgaaaccccagccccggc
acatctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctgggcataagc
actaccaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggcaactgacgac
gagatggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagtggttctgat
cctcaagacattaatgaacaagaagaatcagaggcgaataccatcgctagcccgccaaac
cccctcccttccagaagagcccactctttgaccacagctgggtcccccaacttggctgcc
gggacgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttcaaacaagagc
ccgtccagtgcttggagcagtagtagctggcacggacggatcaaaggcggcatgaaggga
tttcagagcttcatggtttcagacagcaacatgagttttgttgaatttgttgagctgttc
aaatcgttcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtctatgcagtg
ccctgcagccgatctggatccgagtcagccccgctctacaccaacttgatgattgatgaa
aacaccagcgatcttcagcctgacctagatctgttgaccagaaatgtctcagatttgggg
ttgttcatcaagagtaaacagcagctatcagacaaccagaggcagatatctgatgccatt
gctgctgcaagcatcgtgacaaatggcactgggattgagagcacatctctgggcattttc
ggggtgggcatacttcagctcaacgatttcctcgtgaattgccaaggagaacactgcact
tatgatgaaatcctcagcatcatccagaagtttgagcctaacatcagtatgtgtcatcag
ggactaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaattttgcctca
aaaaatgatgagtcacaggagaacattaaagaactgcagctacccctctcatactattac
atcgaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaatcctcggta
gaactctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggactgctgggac
ggagacgatgggatgcccatcatttatcatggacatacactgacaaccaagatccccttc
aaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatc
atatcgattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaag
actgtgtttggagaaaagctggtggctaaattcttatttgagactgatttctcagatgat
ccaatgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaacaagaaacta
aaagcccatcagacgccagtggatatcttaaagcaaaaggctcatcagttagcatctatg
caagcgcaggcttataatggtgggaatgccaaccccccacctgccaataatgaggaagag
gaagatgaggaggacgaatatgattatgactatgaatccctttctgatgacaacattctg
gaagacagacctgaaaataaatcatgtagtgacaagcttcagtttgagtatagtgaagaa
atccccaagaggataaagaaggcagataactctgcttgcaacaaaggaaaggtttatgat
atggaactgggagaagaattttatcttgatcagaataaaaaggaaagcagacagattgca
ccagagctttctgaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaact
ctaaatgcatctggctctaacagaggaaaggaaaggaaaagcaggaagtccatttttggc
aacaatccgggcagaatgagcccaggggagacagcatcatttaacaaaacatctggaaaa
agttcctgtgaaggcattcgacagacctgggaggaatcttcttcccctctcaacccaacc
acgtccctcagtgctatcattagaactcctaaatgttatcatatctcgtcgctgaatgaa
aatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcataccgcctgt
cagctgctgagaacttaccctgctgccactcgcatcgactcctccaacccgaaccccatc
atgttctggctccatgggatacagctcgtggcactcaactaccagaccgatgatctccct
ttacatttaaatgctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacct
ccagttctgtgggacaagaactgcccgatgtatcagaagttttctccactggaaagagat
ttggacagcatggatcctgtagtctattctttaactattgtctctggtcagaatgtgtgc
cccagtaacagcacgggaagcccgtgcattgaagtcgacgtcctgggcatgcctctggac
agctgccatttccgcacaaagcccatccatcgaaacaccctgaaccccatgtggaacgag
cagtttctgttccgcgttcacttcgaagatcttgtatttcttcgttttgcagttgtggaa
aacaacagttcagcggtaactgctcagagaatcattccactgaaagctttaaaacgaggc
tatcgacatcttcagctgcgaaaccttcacaatgaagtcttggagatctctagtttattc
attaacagcagaaggatggaagaaaattcctctggcagtcccatgtcagcctcttcgatg
tttactacagaagaaagaaaatgtttgcagactcacagagtcacggtgcatggggtccca
gggccagagccctttactgttttcactattaatggaggcaccaaggcaaagcagcttctg
cagcaaattctgacaactgaacaagacatcaaacctgttaccacagactattttttgatg
gaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaaccattccagaga
gccattggtccagaagaggagatcgtgcaaattttaagcagctggtttccagaagaggga
tatgtgggcaggattctcttaaaaacccagcaggaaaacctagaagagaaaaacattgtt
caagatgacaaagaggtgatcttgagctcagaggaggagagtttctttgtccaagtgcat
gatgtttctccagagcaacctcgaacagtcatcaaagcaccccgcgtcagcaccgcacag
gatgtcattcagcagaccttatgcaaagccaaatattcctacagcatcctgagcaacccc
aatccaagtgactatgtgcttctggaagaggtggtgaaagacactaccaacaagaagtct
accacacccaagtcctctcagcgggtccttctggatcaggagtgtgtgtttcaagcccaa
agcaagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggcatct
cgagaagacaaaaagaaaggcatttcttttgcaagtgaactcaagaagctcaccaagtca
actaaacagccccgaggacttacatcaccttctcagctcttgacctcagaaagtatccaa
accaaggaggagaaacctgtgggtggcttgtcctccagtgacacaatggattaccgacag
tga

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