KEGG   Macaca mulatta (rhesus monkey): 703088Help
Entry
703088            CDS       T01028                                 

Gene name
TGFBR2
Definition
transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)
Orthology
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    703088 (TGFBR2)
   04350 TGF-beta signaling pathway
    703088 (TGFBR2)
   04390 Hippo signaling pathway
    703088 (TGFBR2)
   04068 FoxO signaling pathway
    703088 (TGFBR2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    703088 (TGFBR2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    703088 (TGFBR2)
  Cell communication
   04520 Adherens junction
    703088 (TGFBR2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    703088 (TGFBR2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    703088 (TGFBR2)
   05202 Transcriptional misregulation in cancers
    703088 (TGFBR2)
   05210 Colorectal cancer
    703088 (TGFBR2)
   05212 Pancreatic cancer
    703088 (TGFBR2)
   05220 Chronic myeloid leukemia
    703088 (TGFBR2)
  Infectious diseases
   05166 HTLV-I infection
    703088 (TGFBR2)
   05142 Chagas disease (American trypanosomiasis)
    703088 (TGFBR2)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     703088 (TGFBR2)
Protein kinases [BR:mcc01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   703088 (TGFBR2)
Enzyme-linked receptors [BR:mcc01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   703088 (TGFBR2)
Cytokine receptors [BR:mcc04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   703088 (TGFBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
2
AA seq 567 aa AA seqDB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMMVTDNNGAVKFPQLCKFCDVRFST
CDNQKSCLSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPK
CIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAI
SVIIIFYCYRVNRQQKLSSSWEAGKPRKLMDFSEHCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1704 nt NT seq  +upstreamnt  +downstreamnt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgtatc
gccagcacgatcccaccgcacgttcagaagtcggttaacaatgacatgatggtcactgac
aacaatggtgcagtcaagtttccacaactgtgtaaattttgtgatgtgagattttccacc
tgtgacaaccagaaatcctgcctgagcaactgcagcatcacctccatctgtgaaaagcca
caggaagtctgtgtggctgtatggagaaagaatgacgagaacataacactagagacagtt
tgccatgatcccaagctcccctaccatgactttattctggaagatgctgcttctccaaag
tgcattatgaaggaaaaaaaaaagcctggtgagactttcttcatgtgttcctgtagctct
gatgagtgcaatgacaacatcatcttctcagaagaatacaacaccagcaatcctgacttg
ttgctagtcatatttcaagtgacaggcatcagcctcctgccaccactgggagttgccata
tctgtcatcatcatcttctactgctaccgcgttaaccggcagcagaagctgagctcatcc
tgggaagctggcaagccacggaagctcatggacttcagcgagcactgtgccatcatcctg
gaagacgaccgctccgacatcagctccacatgcgccaacaacatcaaccacaacacagag
ctgctgcccattgaactggacaccctggtggggaaaggtcgctttgctgaggtctataag
gccaagctgaagcagaacacttcagagcagtttgagacagtggcagtcaagatctttccc
tatgaggagtatgcctcttggaagacggagaaggacatcttctcagacatcaacctgaag
catgagaacatactccagttcctgacagctgaggagcgcaagacggagttggggaagcag
tactggctgatcactgccttccatgccaagggcaacctacaggagtacctgacgcggcat
gtcatcagctgggaggacctgcgcaaactgggcagctccctcgcccggggcattgcccac
ctccacagtgatcacactccgtgcgggaggcccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctcgtgaagaacgacctgacctgctgcctgtgtgactttgggctt
tccctgcgtctggaccctactctgtctgtggatgacctggctaacagcgggcaggtggga
actgcaagatacatggctccagaagtcctagaatccaggatgaatttggagaatgtagag
tcctttaagcagaccgatgtctactccatggctctggtgctctgggaaatgacatcgcgc
tgtaatgcggtgggagaagtaaaagattatgagcctccatttggttccaaggtgcgggag
cacccctgtgtcgaaagcatgaaggacaacgtgttgagagatcgaggacgaccagaaatt
cccagcttctggctcaaccaccagggcatccagatggtgtgtgagacgttgactgagtgc
tgggaccacgacccagaggcccgcctcacagcccagtgtgtggcagaacgcttcagtgag
ctggagcacctggacaggctctcggggaggagctgctccgaggagaagattcctgaagac
ggctccctaaacactaccaaatag

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