KEGG   Macaca mulatta (rhesus monkey): 706009Help
Entry
706009            CDS       T01028                                 

Gene name
INSR, IR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    706009 (INSR)
   04015 Rap1 signaling pathway
    706009 (INSR)
   04010 MAPK signaling pathway
    706009 (INSR)
   04066 HIF-1 signaling pathway
    706009 (INSR)
   04068 FoxO signaling pathway
    706009 (INSR)
   04072 Phospholipase D signaling pathway
    706009 (INSR)
   04022 cGMP - PKG signaling pathway
    706009 (INSR)
   04151 PI3K-Akt signaling pathway
    706009 (INSR)
   04152 AMPK signaling pathway
    706009 (INSR)
   04150 mTOR signaling pathway
    706009 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    706009 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    706009 (INSR)
   04923 Regulation of lipolysis in adipocyte
    706009 (INSR)
   04913 Ovarian Steroidogenesis
    706009 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    706009 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    706009 (INSR)
   04213 Longevity regulating pathway - multiple species
    706009 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    706009 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    706009 (INSR)
   04931 Insulin resistance
    706009 (INSR)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     706009 (INSR)
Protein kinases [BR:mcc01001]
 Tyrosine protein kinases
  InsR family [OT]
   706009 (INSR)
Enzyme-linked receptors [BR:mcc01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   706009 (INSR)
Cytokine receptors [BR:mcc04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   706009 (INSR)
CD molecules [BR:mcc04090]
 Proteins
  706009 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
19
AA seq 1096 aa AA seqDB search
MNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAE
LEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWD
WSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELL
KFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVD
IDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDAT
NPSVPLDPTQCLTHIPDYSEVETAFGDPNGKHPPLPGFLGEGSGRHGSSHPFPYVSVYVW
CVCGACVWMCARVCVFSRRDVSPAFLFLSPGLKLPSRTWSPPFESEDSQKHNQSEYEDSA
GECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGD
VGNVTVAVPTVAAFPNTSSTSTPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACN
QDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEV
SYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTD
YLDVPSNIAKIIIGPLIFVFLFSIVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVF
PCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLR
ERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP
GRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYE
TDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVL
KFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHS
EENKAPENEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNG
GKKNGRILTLPRSNPS
NT seq 3291 nt NT seq  +upstreamnt  +downstreamnt
atgaattccagcaacttgctgtgcaccccgtgcctgggtccctgtcccaaggtatgccac
ctcctagaaggcgagaagaccatcgactcggtgacgtctgcccaggagctccgaggatgc
accgtcatcaacgggagtctgatcatcaacattcgaggaggcaataatctggcagctgag
ctagaagccaacctcggcctcattgaagaaatttcaggttatctaaaaatccgccgatcc
tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg
gaaatcgggaactattccttctatgccttggacaaccagaacctaaggcagctctgggac
tggagcaaacacaacctcacgatcactcaggggaaactcttcttccactataaccccaaa
ctctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag
agaaatgacattgccctgaagacaaatggggaccaggcatcctgtgaaaatgagttactt
aaattttcttacattcggacatctttcgataagatcttgctgagatgggagccgtactgg
ccccccgacttccgagacctcctggggttcatgctgttctacaaagaagccccttaccag
aatgtgacggagtttgatgggcaggatgcgtgtggttccaacagctggacggtggtagac
attgacccgcccctgaggtccaacgaccccaaatcacagaaccacccaggatggctaatg
cggggtctcaagccctggacccagtatgccatctttgtgaagaccctggtcaccttttcg
gatgaacgccggacctatggagccaagagtgacatcatttatgtccagacagatgccacc
aacccctccgtgcccctggatccaactcagtgtctaactcatatcccagattattctgaa
gtggaaaccgccttcggggaccccaatggcaaacatccccccctacctggttttctggga
gagggcagcggaagacacggaagcagccatcccttcccgtatgtctcagtgtatgtgtgg
tgtgtgtgtggtgcgtgtgtgtggatgtgtgcgcgtgtgtgtgtgttcagccgcagagac
gtgagcccggcttttctgtttctttctccagggctgaagctgccctcgaggacctggtct
ccaccattcgagtctgaagattctcagaagcacaaccagagtgaatatgaggattcagcc
ggtgaatgttgctcctgtccaaagacagactctcagatcctgaaggagctggaggagtcc
tcgtttaggaagacgtttgaggattacctgcacaacgtggttttcgtccccagaaaaacc
tcttcaggcactggtgccgaggaccctaggccatctcggaaacgcaggtcccttggcgat
gttgggaatgtgacggtggccgtgcccacggtggcagctttccccaacacttcctcgacc
agcacgcccacaagtccggaggagcacaggccctttgagaaggtggtgaacaaggagtcg
ctggtcatctccggcttgcgacacttcacgggctatcgcatcgagctgcaggcttgcaac
caagacacccccgaggaacggtgcagtgtggcagcctacgtcagcgccaggaccatgcct
gaagccaaggctgatgacattgttggccctgtgacgcatgaaatctttgagaacaacatc
gtccacttgatgtggcaggagccgaaggagcccaatggtctgattgtgctgtatgaagtg
agttatcggcgatatggcgatgaggagctgcatctctgtgtctcccgcaagcacttcgct
ctggaacggggctgcaggctgcgcgggctgtcgccggggaactacagcgtgcgagtccgg
gccacctccctcgcgggcaacggctcctggacggaacccacctatttctacgtgacggac
tatttagatgtcccgtcaaatattgcaaaaattatcatcggccccctcatctttgtcttt
ctcttcagtattgtgattggaagtatttatctattcctgagaaagaggcagccagatggg
ccgctgggaccgctttacgcttcttcaaaccctgagtatctcagtgccagtgatgtgttt
ccatgctctgtgtacgtgccggacgagtgggaggtgcctcgagagaagatcaccctcctt
cgagagctggggcagggctccttcggcatggtgtatgagggcaacgccagggacatcatc
aagggtgaggcagagacccgcgtggcagtgaagacggtcaacgagtcagccagtctccga
gagcggattgagttcctcaatgaggcctcggtcatgaagggcttcacctgccatcatgtg
gtgcgcctcctgggagtggtgtccaagggccagcccacgctggtggtgatggaactgatg
gctcacggagacctgaagagctacctccgttctctgcggccagaggctgagaataatcct
ggccgccctccccctaccctgcaagagatgattcagatggcggcggagattgctgacggg
atggcctacctgaatgccaagaagttcgtgcatcgggacctggcagcgagaaactgcatg
gtcgcccatgattttactgtcaaaatcggagactttggaatgaccagagacatatatgaa
acggattactaccggaaaggaggcaagggtctgctccctgtacggtggatggcaccggag
tccctgaaggatggggtctttaccacttcttctgacatgtggtcctttggcgtggtcctt
tgggaaatcaccagcttggcagaacagccttaccaaggcctgtctaatgaacaggtgttg
aaatttgtcatggacggagggtatctggatcaacccgacaactgtccagagagagtcact
gacctcatgcgcatgtgctggcaattcaaccccaagatgaggccaaccttcctggagatc
gtcaacctgctcaaggacgacctgcaccccagctttccggaggtgtcgttctttcacagc
gaggagaacaaggctcccgagaatgaggagctggagatggagtttgaggacatggagaac
gtgcccctggaccgttcctcgcactgtcagagggaggaggcggggggccgggatggaggg
tcctcgctgggtttcaagcggagctacgaggaacacatcccttatacccacatgaacgga
ggcaagaaaaacgggcggattctgaccttgcctcggtccaatccttcctaa

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