KEGG   Macaca mulatta (rhesus monkey): 707870Help
Entry
707870            CDS       T01028                                 

Gene name
IRS4
Definition
insulin receptor substrate 1-like
Orthology
K16172  
insulin receptor substrate 1
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
FoxO signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Neurotrophin signaling pathway
Insulin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
MicroRNAs in cancer
Class
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:mcc04068]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:mcc04151]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:mcc04150]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:mcc04910]
Organismal Systems; Endocrine system; Adipocytokine signaling pathway [PATH:mcc04920]
Organismal Systems; Excretory system; Aldosterone-regulated sodium reabsorption [PATH:mcc04960]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:mcc04722]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:mcc05206]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:mcc04930]
Human Diseases; Endocrine and metabolic diseases; Non-alcoholic fatty liver disease (NAFLD) [PATH:mcc04932]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
12
AA seq 1252 aa AA seqDB search
MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HDGAAALGAGGGGGSCSGSSGVGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN
GHYILSRGGNGHRYTPGTGLGTSPALAGDEASSAADLDNRFRKRTHSAGTSPTITHQKTP
SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHPLERRGGHHR
PDSSTLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
GYMMMSPSGGCSPDIGGGPSSSSSSAVPSGSSYGKLWTNGVGGHHSHVLPHPKPPVESSG
GKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEE
GARHQHLRLSASSGRLLYAATVDDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLP
RKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQQQQQQQQQQQQPLLHPPEPK
SPGEYVNIEFGSDQPGYLSGPVASRSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRR
AAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPIAPVS
YADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSA
FTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAIGGGGGS
SSSSEDVKRHSSASFENVWLRPGELGGAPKEPAQLCGAAGGLENGLNYIDLDLVKDFKQR
PQECSPHPQPPPPPPPHQPLGSSESSSTRRRSSEDLSAYASISFQKQPEDLQ
NT seq 3759 nt NT seq  +upstreamnt  +downstreamnt
atggcgagccctccggagagcgatggcttctcggacgtgcgcaaggtgggctacctgcgc
aaacccaagagcatgcacaaacgcttcttcgtactgcgcgcggccagcgaggctgggggc
ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatcccccttgagagctgcttcaacatcaacaagcgggctgactccaagaac
aagcacctggtggctctctacacccgggacgagcactttgccatcgcggcggacagcgag
gcggagcaagacagctggtaccaggctctcctacagctgcacaaccgtgccaagggccac
cacgacggagctgcggccctcggggcgggaggtggcgggggcagctgcagtggcagctcc
ggcgttggtgaggctggggaggacttgagctacggtgacgtgcccccaggacccgcgttc
aaagaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacctgatt
ggtatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag
gcagccgccgtggtgctgcagctgatgaacatcaggcgctgcggccactcggagaacttc
ttcttcatcgaggtgggccgttctgccgtgacggggcccggggagttctggatgcaggtg
gatgactccgtggtggcccagaacatgcacgagaccatcctggaggccatgcgggctatg
agcgatgagttccgccctcgcagcaagagtcagtcctcgtccaactgctccaaccccatc
agcgtccccctgcgccggcaccatctcaacaaccccccgcccagccaggtggggctgacc
cgacgatctcgcactgagagcatcactgccacctccccggccagcatggtgggcgggaaa
ccaggctccttccgcgtccgcgcctccagtgacggcgaaggcaccatgtcccgcccagcc
tcggtggatggcagccctgtgagtccgagcaccaacagaacccacgcccaccggcatcgg
ggcagcgcccggctgcaccccccgctcaaccacagccgctccatccccatgccagcttcc
cgctgctcgccttcggccaccagccccgtcagtctgtcgtccagcagcaccagcggccat
ggctccacctcggattgtctcttcccacggcgatctagtgcttcggtgtctggttctccc
agcgatggcggtttcatctcctcagatgagtatggctccagtccctgcgatttccggagt
tccttccgcagtgtgactccggattccctgggccacaccccaccagcccgcggtgaggag
gagctaagcaactatatctgcatgggcggcaaggggccctccaccctgaccgcccccaac
ggtcactacattttgtctcggggtggcaatggccaccgctacaccccaggaacaggcttg
ggcacgagtccagccttggctggggatgaagcatccagtgctgcggatctggataatcgc
ttccgaaagagaactcactctgcaggcacatcccctaccattacccaccagaagaccccg
tcccagtcctcagtggcttccattgaggagtatacagagatgatgcctgcctacccacca
ggaggtggcagtggaggccgactgccgggacacaggcactctgccttcgtgcccacccac
tcctacccagaggagggtctggaaatgcaccccttggagcgtcgggggggccaccaccgc
ccagacagctctaccctccacactgatgatggctacatgcccatgtccccaggggtggcc
ccagtgcccagcagccgaaagggcagtggagactatatgcccatgagccccaagagcgtg
tctgccccacagcagatcatcaatcccatcagacgccatccccagagagtggaccccaat
ggctacatgatgatgtcccccagcggtggctgctctcctgacattggaggtggccccagc
agcagcagcagcagtgctgtcccttctgggagcagctatggaaagctgtggacaaacggg
gtagggggccaccactctcatgtcttgcctcaccccaaacccccagtggagagcagcggt
ggcaagctcttaccttgcacaggtgactacatgaacatgtcaccagtgggggactccaac
accagcagcccctctgactgctactatggccctgaggacccccagcacaagccagtcctc
tcgtactactcattgccaagatcctttaagcacacccagcgccctggggagccggaggag
ggtgcccggcatcagcacctccgcctttctgctagctctggtcgccttctctatgctgca
acagtggatgattcttcctcctccaccagcagcgacagcctgggtgggggatactgtggg
gctaggctggagcccagccttccacatccccaccatcaggttctgcagccccatctgcct
cgaaaggtggacacagctgctcagaccaatagccgcctggcccggcctacgaggctgtcc
ctgggggatcccaaggccagcaccttacctcgggcccgagagcagcagcagcagcagcag
cagcagcagcagcagcaacagcagcaacagcagcccctgctgcaccctccggagcccaag
agcccaggggaatatgtgaatattgaatttgggagtgatcagcctggctacttgtctggc
ccggtggcttcccgtagctcaccttctgtcaggtgtccatcccagctccagccagctccc
agagaggaagagactggcactgaggagtacatgaagatggacctggggccgggccggagg
gcagcctggcaggagagcactggggtcgagatgggcagactggggcccgcacctcccggg
gctgctagcatttgcaggcctacccgggcagtgcccagcagccggggtgactatatgacc
atgcagatgagttgtccccgccagagctatgtggacacctcgccaattgcccctgtaagc
tatgctgacatgcggacaggcattgctgcagaggaggtgagcctgcccagggccaccatg
gctgctgcctcctcatcctcagcagcctctgcttcccccactgggcctcaaggggcagca
gagctggctgcccactcatccctgctggggggcccacaaggacctgggggcatgagcgcc
ttcacccgggtgaacctcagtcctaaccgcaaccagagtgccaaagtgatccgtgcagac
ccacaagggtgccggaggaggcatagctccgagaccttctcctcaacacccagtgccacc
cgggtgggcaacacagtgccctttggagccggggcagcaatagggggtggtggcggtagc
agcagcagcagcgaggatgtgaaacgtcacagctctgcttcctttgagaatgtgtggctg
aggcctggggaacttgggggagcccccaaggagccagcccaactgtgtggggctgctggg
ggtttggagaatggtcttaactacatagatctggatttggtcaaggacttcaaacagcgc
cctcaggagtgcagccctcacccacagcctcccccacccccaccccctcatcaacccctg
ggtagcagtgagagcagctccacccgccgccgctcaagtgaggatttaagcgcctatgcc
agcatcagtttccagaagcagccagaggaccttcagtag

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