KEGG   Macaca mulatta (rhesus monkey): 708938Help
Entry
708938            CDS       T01028                                 

Gene name
MAPK3
Definition
mitogen-activated protein kinase 3-like
Orthology
K04371  
mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
mTOR signaling pathway
PI3K-Akt signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Dorso-ventral axis formation
TGF-beta signaling pathway
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Adherens junction
Gap junction
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Circadian entrainment
Long-term potentiation
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Aldosterone-regulated sodium reabsorption
Alzheimer's disease
Prion diseases
Alcoholism
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    708938 (MAPK3)
   04015 Rap1 signaling pathway
    708938 (MAPK3)
   04010 MAPK signaling pathway
    708938 (MAPK3)
   04012 ErbB signaling pathway
    708938 (MAPK3)
   04350 TGF-beta signaling pathway
    708938 (MAPK3)
   04370 VEGF signaling pathway
    708938 (MAPK3)
   04668 TNF signaling pathway
    708938 (MAPK3)
   04066 HIF-1 signaling pathway
    708938 (MAPK3)
   04068 FoxO signaling pathway
    708938 (MAPK3)
   04022 cGMP - PKG signaling pathway
    708938 (MAPK3)
   04151 PI3K-Akt signaling pathway
    708938 (MAPK3)
   04150 mTOR signaling pathway
    708938 (MAPK3)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    708938 (MAPK3)
  Cell growth and death
   04114 Oocyte meiosis
    708938 (MAPK3)
  Cell communication
   04510 Focal adhesion
    708938 (MAPK3)
   04520 Adherens junction
    708938 (MAPK3)
   04540 Gap junction
    708938 (MAPK3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    708938 (MAPK3)
   04620 Toll-like receptor signaling pathway
    708938 (MAPK3)
   04621 NOD-like receptor signaling pathway
    708938 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    708938 (MAPK3)
   04660 T cell receptor signaling pathway
    708938 (MAPK3)
   04662 B cell receptor signaling pathway
    708938 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    708938 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    708938 (MAPK3)
   04062 Chemokine signaling pathway
    708938 (MAPK3)
  Endocrine system
   04910 Insulin signaling pathway
    708938 (MAPK3)
   04912 GnRH signaling pathway
    708938 (MAPK3)
   04915 Estrogen signaling pathway
    708938 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    708938 (MAPK3)
   04917 Prolactin signaling pathway
    708938 (MAPK3)
   04921 Oxytocin signaling pathway
    708938 (MAPK3)
   04919 Thyroid hormone signaling pathway
    708938 (MAPK3)
   04916 Melanogenesis
    708938 (MAPK3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    708938 (MAPK3)
   04270 Vascular smooth muscle contraction
    708938 (MAPK3)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    708938 (MAPK3)
  Nervous system
   04724 Glutamatergic synapse
    708938 (MAPK3)
   04725 Cholinergic synapse
    708938 (MAPK3)
   04726 Serotonergic synapse
    708938 (MAPK3)
   04720 Long-term potentiation
    708938 (MAPK3)
   04730 Long-term depression
    708938 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    708938 (MAPK3)
   04722 Neurotrophin signaling pathway
    708938 (MAPK3)
  Development
   04320 Dorso-ventral axis formation
    708938 (MAPK3)
   04360 Axon guidance
    708938 (MAPK3)
   04380 Osteoclast differentiation
    708938 (MAPK3)
  Environmental adaptation
   04713 Circadian entrainment
    708938 (MAPK3)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    708938 (MAPK3)
   05205 Proteoglycans in cancer
    708938 (MAPK3)
   05203 Viral carcinogenesis
    708938 (MAPK3)
   05210 Colorectal cancer
    708938 (MAPK3)
   05212 Pancreatic cancer
    708938 (MAPK3)
   05214 Glioma
    708938 (MAPK3)
   05216 Thyroid cancer
    708938 (MAPK3)
   05221 Acute myeloid leukemia
    708938 (MAPK3)
   05220 Chronic myeloid leukemia
    708938 (MAPK3)
   05218 Melanoma
    708938 (MAPK3)
   05211 Renal cell carcinoma
    708938 (MAPK3)
   05219 Bladder cancer
    708938 (MAPK3)
   05215 Prostate cancer
    708938 (MAPK3)
   05213 Endometrial cancer
    708938 (MAPK3)
   05223 Non-small cell lung cancer
    708938 (MAPK3)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    708938 (MAPK3)
   05020 Prion diseases
    708938 (MAPK3)
  Substance dependence
   05034 Alcoholism
    708938 (MAPK3)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    708938 (MAPK3)
  Infectious diseases
   05132 Salmonella infection
    708938 (MAPK3)
   05133 Pertussis
    708938 (MAPK3)
   05152 Tuberculosis
    708938 (MAPK3)
   05164 Influenza A
    708938 (MAPK3)
   05161 Hepatitis B
    708938 (MAPK3)
   05160 Hepatitis C
    708938 (MAPK3)
   05145 Toxoplasmosis
    708938 (MAPK3)
   05140 Leishmaniasis
    708938 (MAPK3)
   05142 Chagas disease (American trypanosomiasis)
    708938 (MAPK3)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     708938 (MAPK3)
Protein kinases [BR:mcc01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   708938 (MAPK3)
Exosome [BR:mcc04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   708938 (MAPK3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
20
AA seq 430 aa AA seqDB search
MESCPPRLGPQVLGVIGKVTPWPLRLREEGEDSLRGGAAEPPRHLVTAEPAETPGLPHLG
REGRARARGGSRDGSRPARGRGRAGPGQGRGLERAALPQQQPLSGPLSSAYDHVRKTRVA
IKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDL
YKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR
IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH
YLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDR
MLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETA
RFQPGALEAP
NT seq 1293 nt NT seq  +upstreamnt  +downstreamnt
atggagagctgtcccccaaggctggggcctcaggtgcttggggtgataggaaaggtcacg
ccctggccgcttcgccttcgagaggagggtgaggacagtctccgaggcggcgctgccgag
cctccccgtcacttggtgaccgcggagccagcagagaccccggggctcccgcacctaggg
cgagaagggcgggcgcgcgcccggggtgggtcacgtgacggctccaggcccgcgcggggc
cgggggcgcgcggggccggggcaggggcggggcctggagcgcgcggccctgccacagcag
cagcctctctccggtcccctcagctcggcctatgaccacgtgcgcaagactcgcgtggcc
atcaagaagatcagccccttcgagcatcagacctactgccagcgcacgctccgggagatc
cagatcctgctgcgcttccgccatgagaatgtcatcggcatccgagacattctgcgtgcg
tccaccctggaagccatgagggatgtctacattgtgcaggacctgatggagactgacctg
tacaagttgctgaaaagccagcaactgagcaatgaccacatctgctacttcctctaccag
atcctgcggggcctcaagtacatccactccgctaatgtgctccaccgggatctaaagccc
tccaacctgctcatcaacaccacctgcgaccttaagatttgcgatttcggcctggcccgg
attgccgatcctgagcatgaccacaccggcttcctgacggagtatgtggctacacgctgg
taccgggccccagagatcatgctgaactccaagggctataccaagtccatcgacatctgg
tctgtgggctgcattctggctgagatgctctctaaccggcccatcttccctggcaagcac
tacctggatcagctcaaccacattctgggcatcctgggctccccatcccaggaggacctg
aattgtatcatcaacatgaaggcccgaaactacctacagtctctgccctccaagaccaag
gtggcttgggccaagcttttccccaagtcagactccaaagcccttgacctgctggaccgg
atgttaacctttaaccccaataaacggatcacagtggaggaagcgctggctcacccctac
ctggagcagtactatgacccgacggatgagccagtggccgaggagcccttcaccttcgcc
atggagctggatgacctacctaaggagcggctgaaggagctcatcttccaggagacagca
cgcttccagcctggggcgctagaggccccctaa

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