| Entry |
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| Gene name |
USP8
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| Definition |
(RefSeq) ubiquitin specific peptidase 8
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| KO |
| ubiquitin carboxyl-terminal hydrolase 8 [EC: 3.4.19.12] |
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| Organism |
mcc Macaca mulatta (rhesus monkey)
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| Pathway |
| Mitophagy - animal | | Endocytosis | | Cushing's syndrome |
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| Brite |
KEGG Orthology (KO) [BR:mcc00001]
Cellular Processes
Transport and catabolism
04144 Endocytosis
715523 (USP8)
04137 Mitophagy - animal
715523 (USP8)
Human Diseases
Endocrine and metabolic diseases
04934 Cushing's syndrome
715523 (USP8)
Enzymes [BR:mcc01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
715523 (USP8)
Peptidases [BR:mcc01002]
Cysteine Peptidases
Family C19: ubiquitin-specific protease family
715523 (USP8)
Membrane trafficking [BR:mcc04131]
Endosome - Lysosome transport
Others
Others
715523 (USP8)
Ubiquitin system [BR:mcc04121]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
UBP/USP
715523 (USP8)
 |
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: Ensembl: UniProt: |
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| Position |
7
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| AA seq |
1118 aa  
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY
VLYMKYVTVYNLIKKRPDFKQQQDYFHSVLGPANIKKAVEEAERLSESLKLRYEEAEVRK
KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK
GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP
DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTVLRSLKDALFKWESKTILRNEPLVLEGG
YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESVPSKPAAQIPPPSIEVDE
NIELISDQNERMGPLNISTPAEPVAASKSDVSPIIQPVPSIKNIPQIDRTKKPAVKLPEE
HRTKSESTNHEQQSPQNGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK
ELRERQQEEQKEKLRREEQEQKTKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET
SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEVQKKSTGDVPHTSATGDSGSS
KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD
PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP
DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR
NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG
QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNEH
LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS
KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW
KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW
FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT |
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| NT seq |
3357 nt  +upstreamnt +downstreamnt
atgcctgctgtggcttcagttcctaaagaactctacctcagttcttcactaaaagacctc
aataagaagacggaagttaaaccagagaaaataagcactaagagttatgtgcacagtgcc
ctgaagatctttaagacagcagaagaatgcagattagatcgtgatgaggaaagggcctat
gtgctatatatgaaatacgtgactgtttataatcttatcaaaaaaagacctgatttcaag
caacagcaggattatttccattcagttcttggacctgcaaacatcaaaaaagccgttgaa
gaagccgaaagactctctgaaagccttaaactaagatatgaagaagccgaagtccggaaa
aaacttgaggaaaaggacaggcaggaggaagcacagcggctacaacagaaaagacaggaa
acaggaagagaggatggtggcacgttggctaaaggttctttggagaatgtattggattcc
aaagacaaaacccaaaagagcaatggtgaaaagaatgaaaaatgtgagaccaaagagaaa
ggagcaatcacagcaaaggaactatacacaatgatgacggataaaaacatcagcttgatt
ataatggatgctcgaagaatgcaggattatcaggattcctgtattttacattctctcagt
gttcctgaagaagccatcagtccaggagtcactgctagttggattgaagcacacctccca
gatgattctaaagacacatggaagaagagggggaatgtggagtatgtggtacttcttgac
tggtttagttctgccaaagatttacagattggaacagttctccggagtctgaaagatgca
cttttcaagtgggaaagtaaaactatcctgcgcaatgagcctttggttttagagggaggc
tatgaaaactggctcctttgttatccccagtatacaacaaatgctaaggtcactccaccc
ccacgacgccagaatgaagaggtgtctatctcattggattttacttatccctcattggaa
gaatcagttccttctaaacctgctgcccagataccacctccatctatagaagtagatgaa
aatatagaattgataagtgatcaaaatgagagaatgggaccactgaatatatcaactcca
gctgaaccagttgctgcttctaaatctgatgtttcacccataattcagccagtgcctagt
ataaagaatattccacagattgatcgtactaaaaaaccagcagtcaaattgcctgaagag
catagaacaaaatctgaaagtacaaaccatgagcaacaatctcctcagaatggaaaagtt
attcctgatcgttccaccaagccagtagttttctctccaactctcatgttaacagatgaa
gaaaaggctcgtattcatgcagaaactgctcttctaatggagaaaaacaaacaagaaaaa
gaacttcgggaaaggcagcaagaggaacagaaagagaaactgaggagggaagaacaagaa
caaaaaaccaaaaagaaacaagaagctgaagaaaatgaaattacagagaagcaacaaaaa
gcaaaagaagaaatggagaagaaagaaagtgaacaggccaagaaagaagataaagaaacc
tcagcaaagaggggcaaagaaataacaggagtaaaaagacaaagtaaaagtgaacatgaa
acttctgatgccaagaaatctgtagaagacagggggaaaaggtgtccaaccccagaagta
cagaagaagtcaacaggagatgtgccccatacatctgcgacaggggattcgggttcaagc
aagccatttaagattaaaggacaaccagaaagtggaattctaaggacaggaacttttaga
gaggatacagacgataccgaaagaaataaagctcaacgagaacctttgacaagagcacga
agtgaagaaatgggaaggattgtaccaggactgccttcaggctgggccaagtttcttgac
ccaatcactggaacctttcgttattatcattcacccaccaacactgttcatatgtaccca
ccggaaatggctccttcatctgcacctccttccacccctccaactcataaagccaagcca
cagattcctgctgagcgggatagggaaccttccaaactgaagcgttcctactcctcccca
gatataacccaggctattcaggaggaagagaagaggaagccaacagtaactccaacggtt
aatcgagaaaacaagccaacatgttatcctaaagctgagatctcaaggctttctgcttct
cagattcggaacctcaatcctgtttttggaggttctggaccagctcttactggacttcgt
aacttaggaaatacttgttatatgaactcaatattgcagtgcctatgtaatgctccacat
ttggctgattatttcaaccgaaactgttatcaggatgatattaacaggtcaaatttgttg
gggcataaaggtgaagtggcagaagaatttggtataatcatgaaagccctgtggacagga
cagtatagatatatcagtccaaaagactttaaaatcaccattgggaagatcaatgaccag
tttgcaggatacagtcagcaagattcacaagaattgcttctgttcctgatggatggtctc
catgaagatctaaataaagctgataatcggaagagatataaagaagaaaataatgaacat
cttgatgactttaaagctgcagaacatgcctggcagaaacacaagcagctcaatgagtct
attattgttgcactttttcagggtcaattcaaatctacagtacagtgcctcacctgtcac
aaaaagtctaggacatttgaggccttcatgtatttgtctctgccgctagcatccacaagt
aaatgtacattacaggattgccttagattattttccaaagaagaaaaactcacagataac
aacagattttactgcagtcattgcagagctcgacgagattctctaaaaaagatagaaatc
tggaagttaccacctgtacttttagtgcatctgaaacgtttttcctacgatggcaggtgg
aaacaaaaattacagacatctgtggacttcccgttagaaaaccttgacttgtcacagtat
gttattggtccaaagaacaatttgaagaaatataatttgttttctgtttcaaatcactac
ggcggactggatggaggccactacacagcctattgtaaaaatgcagcaagacaacggtgg
tttaagtttgatgatcatgaagtttctgatatctccgtttcttctgtgaaatcgtcagca
gcttacatcctcttttatacttcactgggaccacgagtaactgatgtagccacataa |
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