KEGG   Macaca mulatta (rhesus monkey): 718418Help
Entry
718418            CDS       T01028                                 

Gene name
PLCB4
Definition
phospholipase C, beta 4
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mcc00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:mcc04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:mcc04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:mcc04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mcc04070]
Cellular Processes; Cell communication; Gap junction [PATH:mcc04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:mcc04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:mcc04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:mcc04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:mcc04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:mcc04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:mcc04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mcc04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:mcc04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:mcc04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:mcc04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:mcc04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:mcc04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:mcc04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:mcc04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:mcc04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:mcc04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:mcc04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:mcc04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:mcc04720]
Organismal Systems; Nervous system; Long-term depression [PATH:mcc04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:mcc04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mcc04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:mcc04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:mcc05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:mcc05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:mcc05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:mcc05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:mcc05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
10
AA seq 1169 aa AA seqDB search
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVL
ECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE
VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPHLSPSLCMFLLTEQLEALRSMMEAGESASPANILEDDNE
EEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKASDDLEHENNKKGLVTVEDEQ
AWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKT
HAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFE
YNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDM
YGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRI
LPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITE
KRADQMRAMGIETSDIADVPSDTSKNDKKGKANTTKANVTPQSSSELRPTTTAALASGVE
AKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVA
QYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSE
MINTHSAEEQEIRDLHLSQQCELLKKLLISAHEQQTQQLKLSHDRESKEMRAHQAKISME
NSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEF
LEKQNEQAKEMQQMVKLEAEMDRRPATVV
NT seq 3510 nt NT seq  +upstreamnt  +downstreamnt
atggccaaaccttatgaatttaactggcagaaggaagttccttcctttttgcaagaagga
gcagtttttgacagatacgaagaggaatcctttgtgtttgaacccaactgcctcttcaaa
gtggatgagtttggcttctttctgacatggaaaagtgaaggcaaggaaggacaggtgcta
gaatgctccctcatcaacagtattcggtcgggagccataccaaaggatcccaaaatcttg
gctgctcttgaagctgttggaaaatcagaaaatgatctggaaggtcggatagtttgtgtc
tgcagtggcacagatctagtgaacattagttttacctacatggtggctgaaaatccagaa
gtaactaagcaatgggtagaaggcctgagatcaatcatacacaacttcagggccaacaat
gtcagtccaatgacgtgcctcaagaaacactggatgaaattggcatttatgaccaacaca
aatggtaaaattccagttaggagtattactagaacctttgcatcggggaaaacagaaaag
gtgatctttcaagcactcaaggagttaggtcttcccagtggaaagaatgatgaaattgag
cccacggcatttacttatgaaaagttctatgaactgacacaaaagatttgtcctcggaca
gatatagaagatcttttcaaaaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcgattgaatgaaattttattt
ccattttatgatgccaaaagggcaatgcagatcattgagatgtatgaacctgatgaagat
ttgaagaaaaaaggccttatatcaagtgatgggttttgcagatatctgatgtcagatgaa
aacgccccagtcttcctagatcgtttagaactttaccaagaaatggaccatcctctggct
cactacttcatcagttcttcccataacacttacctgactggcagacagttcggcgggaag
tcttcggtagagatgtacagacaggttctcctggctggttgcagatgtgttgaacttgac
tgctgggatggaaaaggtgaagaccaagaaccaataataactcatggaaaagcaatgtgt
acagatatcctttttaaggatgtaattcaagccatcaaggaaactgcatttgtcacatca
gaatatcctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg
tccaaatattgcgaagatctatttggagatctcctgttgaaacaagcgcttgaatcacat
ccacatctgtcaccatctctttgcatgtttttgctaacagaacagctggaagctttgaga
agcatgatggaagctggagaatctgcctccccagcaaacatcttagaggatgataatgaa
gaggagatcgaaagtgctgaccaagaggaggaagctcaccccgaattcaaatttggaaat
gaactttctgctgatgacttgggtcacaaggaagctgttgcaaatagcgtcaagaaggcc
tcagatgaccttgaacatgaaaacaacaaaaagggcctggtaactgtagaagatgagcag
gcgtggatggcatcttataaatatgtaggtgctaccactaatatccatccatatttgtcc
acaatgatcaactacgcccagcctgtaaagtttcaaggtttccatgtggcagaagaacgc
aatattcattataacatgtcttcttttaatgaatcagtcggtcttggctacttgaagaca
catgcaattgaatttgtcaattataacaaacggcaaatgagtcgcatttaccccaaggga
ggccgagtcgattccagtaattacatgcctcagattttctggaacgctggctgccagatg
gtttccctgaactatcaaaccccagatttagcgatgcaattgaatcagggaaaatttgag
tataatggatcgtgcgggtaccttctcaaaccagatttcatgaggcggcctgatcgaaca
tttgaccccttctctgaaactcctgttgatggcgttattgcagccacttgctcagtgcag
gttatatcaggtcaattcttatcagataagaaaattggcacctatgtagaagtggatatg
tatgggttgcccactgacactatacgtaaggaattccgaactcgtatggttatgaataat
ggactaaatccagtttacaatgaagagtctttcgtatttcggaaggtgatcctgccagac
ctggctgtcttgagaatagcagtgtatgatgataacaacaagctgattggccagaggatc
ctcccgcttgatggcctccaagcaggataccgacacatttcccttcgaaatgagggaaat
aaaccattatcactgccaacaattttctgcaatattgttcttaaaacatacgtgcctgat
ggatttggagatattgtggatgctttatcagatccaaagaaatttctctcaattacagaa
aagagagcagaccaaatgagagctatgggcattgaaactagtgacatagctgatgtgccc
agtgacacttccaaaaatgacaagaaaggaaaggccaataccaccaaagcaaacgtgacc
cctcagagtagctctgagctcagaccaaccaccacagctgccctggcctctggtgtggaa
gccaaaaaaggtattgaacttatccctcaagtaaggatagaagatttaaagcagatgaag
gcttacttgaagcatttaaagaaacagcagaaagagctaaattctttaaagaagaaacat
gcaaaggagcacagtaccatgcagaagttacactgcacgcaagttgacaaaattgtggca
cagtatgacaaagagaagtcgactcatgagaaaatcctagagaaggcaatgaagaagaag
gggggaagtaattgtctcgaaatgaaaaaagaaacagaaattaaaattcagacgctgaca
tcagatcacaaatctaaggtcaaagagattgtagcacagcacacaaaggaatggtcagaa
atgatcaatacccacagtgctgaggagcaagaaatccgagacctgcacctcagccagcag
tgtgagctgctgaaaaagctactcatcagtgcccacgagcagcaaacccagcagctgaaa
ctgtcccatgacagggaaagcaaggaaatgcgagcacaccaggctaagatttctatggaa
aatagcaaagccatcagccaagataaatctatcaagaataaggcagaacgggaaaggcga
gtcagggagttaaacagcagcaacactaaaaagtttctggaagaaagaaagagactcgca
atgaagcagtccaaagaaatggatcagttgaaaaaagtccagcttgaacatctagaattc
ctagagaaacagaatgagcaggcgaaggagatgcagcagatggtgaaattggaagccgag
atggaccgcagaccagcaacagtagtatga

DBGET integrated database retrieval system