KEGG   Macaca mulatta (rhesus monkey): 722198Help
Entry
722198            CDS       T01028                                 

Gene name
ARHGEF1
Definition
(RefSeq) Rho guanine nucleotide exchange factor 1
  KO
K12330  
Rho guanine nucleotide exchange factor 1
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Pathways in cancer
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mcc00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    722198 (ARHGEF1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    722198 (ARHGEF1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    722198 (ARHGEF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    722198 (ARHGEF1)
   05205 Proteoglycans in cancer
    722198 (ARHGEF1)
Membrane trafficking [BR:mcc04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    722198 (ARHGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
19
AA seq 1040 aa AA seqDB search
MEDVARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLM
ALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPNVAF
ELDRTRADLISEDVQRRFVQEVVQSQQTAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVG
RDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGVYMRHLGVRTKSGDKKS
GRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFRHLKAEVDAEKPGATD
RKGGLGMPSRDRNVGAPGQDTPGVSLHPLSLDSPDREPGADAPLELGDLSPQGPMSLEPP
APPESTDEGAETERRWKRLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDP
SSATAVLGPARRATPEPGDEGEPGRSGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEV
ISELLVTEAAHVRMLRVLHDLFFQPMADGLFFSLEELQNIFPSLDELIEVHSLFLDRLMK
RRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFV
QEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTEREKVELAAECCREILH
HVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTK
DKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVAT
DHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPRPSPSST
REPLLSSSENGNGGRETSPADGETRGMLARTERILSDLLPFCRPGPEGQLAATALRKGAG
GGILPPATPPVSAWGELCLPAWLHLRSLSRKAFCKKERNGGEDVRDHPHPHSCRSISHPE
GLRRGSCGPRLGGAQLGSLALHEPRPSLPPALCLGDSGLHSGGHHGDPGHLSIACGGHPS
TPHPQVPSLCFYTLNWRFIF
NT seq 3123 nt NT seq  +upstreamnt  +downstreamnt
atggaagacgttgcccgaggggcggcctccccaggcccctcccggcctggcctggttccc
gtcagcatcatcggggcagaggatgaggattttgagaacgagctggagacgaactcagaa
gagcaaaacagccagttccagagcctggagcaggtgaagcggcgcccagcccaccttatg
gccctcctgcagcacgtggccctgcagtttgagccaggacccctgctttgctgtctgcat
gccgacatgctgggctcactgggccccaaggaggccaagaaggccttcctggacttctat
cacagcttcctggagaagacagcggttctgcgggtgccggtccctcccaatgtcgccttt
gaacttgaccgcactcgggctgacctcatctctgaggatgtccagcggcggttcgtgcag
gaggtggtgcaaagccagcagacagccgtgggccggcagctggaggacttccgctccaag
cggctcatgggcatgacgccctgggagcaggagctggcccagctggaggcttgggttggg
cgagaccgagccagctacgaggcccgggagcggcacgtggcggagcgactgctcatgcac
ctggaggagatgcaacataccatctctaccgatgaagaaaagagtgctgccgtggtcaac
gccattggcgtgtacatgcgccaccttggggtgcggaccaagagtggggacaagaagtca
gggaggaacttcttccggaaaaaggtgatggggaaccggcggtcggacgagcctgccaag
accaagaaggggctgagcagcatcctggatgccgcccgctggaaccggggagagccccag
gttccagattttcgacacctcaaagcagaggttgatgctgagaagccaggtgctacagac
cggaagggaggcctggggatgccctctcgggaccggaatgttggggctcctgggcaggac
acccctggagtctctctgcaccctctgtccctggacagcccagaccgggaaccaggtgcc
gacgcccccctggagctgggggacttatccccgcagggcccaatgagcctggagccccca
gcgcccccagagagtaccgatgagggggccgaaaccgagagaaggtggaagaggctatca
gggcgtctggggcgctcagagagcctgcgggtgagtgaccgccgccggccttcccggggc
agcctcggggctaagggccggggtgggggccgctcccggagcgacgtggacatggacccc
agttccgccacggcagtgcttggccctgcccgacgagccacccctgagcctggagatgag
ggggagccggggcggtcaggactggagcttgaaccagaagagcctcctggctggcgggaa
cttgtcccaccagacaccctgcatagcctgcccaagagccaggtgaagcggcaggaggtc
atcagcgagctgctggtgacggaagcggcccacgtgcgcatgctgcgggtgctgcacgac
ctcttcttccagcccatggcggacggcctcttcttctccctggaggagctgcagaacatc
ttccccagcctggacgagctcatcgaggtgcattccctgttcctcgatcgcctgatgaag
cggaggcaggagagtggctacctcatcgaggagattggagacgtgctgctggcccggttt
gatggtgctgagggctcctggttccagaaaatctcctcccgcttctgcagccgccagtcg
tttgccttagagcagctcaaagccaagcaacgcaaggagcctcggttctgtgccttcgtg
caggaagctgagagccgcccacggtgccgccgtctgcagctgaaggacatgattcccacg
gagatgcagcggctgaccaagtaccccctgcttctgcagagcatcgggcagaacacagaa
gagcccacggaacgggagaaagtagagctggcagccgagtgctgccgggaaattctgcac
cacgtcaaccaagccgtgcgtgacatggaggacctgctgaggctcaaggactatcagcgg
cgcctggacttgtcccaccttcgacagagcagcgaccccatgctaagcgagttcaagaac
ctggacatcaccaagaagaaattggtccacgagggcccactgacgtggcgggtgacaaag
gacaaggctgtggaggtgcatgtgctgctgctggatgacctgctgctgctgctccagcgc
caggatgagcggctgctgctcaagtcccatagccggacgctgacgcccacgcccgacggc
aagaccatgctgcggcctgtgctgcggctcacctctgccatgacccgcgaggtggccacc
gatcacaaagccttctacgtcctttttacctgggaccaggaggcccagatatacgagctg
gtggcacagactgtgtcggagcggaagaactggtgtgccctcatcaccgagactgccgga
tccctgaaagtccctgcccctgcctctcgccctaagccccggcccagcccgagcagcacc
cgagaacccctcctcagcagctctgagaacggcaatggtggccgagagacgtctccggct
gatggtgagaccagagggatgctggcccggaccgagagaatcctcagtgacctcctgccc
ttctgcagaccaggccccgagggccagctcgctgccacggcccttcggaaaggagctgga
ggaggaattttgccgcctgcgacccctcctgtctcagcttggggggaactctgtctccca
gcctggctgcacttgaggtccctgtccaggaaggccttttgcaagaaggagaggaatggg
ggagaggacgtgagggaccacccccacccacacagctgccgcagcatctcacaccctgag
ggcctgaggagagggagctgtgggccacgcctgggaggggcccagctggggtcactggcc
ctgcatgagcctcggccatctctccctcctgccctctgcttgggggactcagggcttcat
tccggagggcaccacggtgacccgggccatctcagtattgcctgtgggggccacccctcc
actccccacccccaagtgccttcgctctgtttttataccctgaattggaggtttattttt
taa

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